Motivational factors modulate left frontoparietal network during cognitive control in cocaine addiction
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Scholar |
Otros documentos de la autoría: Barrós-Loscertales, Alfonso; Costumero, Víctor; Rosell Negre, Patricia; Fuentes-Claramonte, Paola; Llopis‐Llacer, Juan‐José; Bustamante, Juan Carlos
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https://doi.org/10.1111/adb.12820 |
Metadatos
Título
Motivational factors modulate left frontoparietal network during cognitive control in cocaine addictionAutoría
Fecha de publicación
2019Editor
WileyISSN
1355-6215; 1369-1600Cita bibliográfica
Barrós‐Loscertales A, Costumero V,Rosell‐Negre P, Fuentes‐Claramonte P, Llopis‐Llacer J‐J,Bustamante JC. Motivational factors modulate leftfrontoparietal network during cognitive control in cocaineaddiction.Addiction Biology. 2019;e12820.https://doi.org/10.1111/adb.12820Tipo de documento
info:eu-repo/semantics/articleVersión de la editorial
https://onlinelibrary.wiley.com/doi/full/10.1111/adb.12820Versión
info:eu-repo/semantics/publishedVersionPalabras clave / Materias
Resumen
Cocaine addiction is characterized by alterations in motivational and cognitiveprocesses involved in goal‐directed behavior. Recent studies have shown thataddictive behaviors can be attributed to alterations in the ... [+]
Cocaine addiction is characterized by alterations in motivational and cognitiveprocesses involved in goal‐directed behavior. Recent studies have shown thataddictive behaviors can be attributed to alterations in the activity of large functionalnetworks. The aim of this study was to investigate how cocaine addiction affectedthe left frontoparietal network during goal‐directed behavior in a stop‐signal task(SST) with reward contingencies by correct task performance. Twenty‐eight healthycontrols (HC) and 30 abstinent cocaine‐dependent patients (ACD) performed SSTwith monetary reward contingencies while undergoing a functional magneticresonance imaging scan. The results showed that the left frontoparietal network(FPN) displayed an effect of cocaine addiction depending on reward contingenciesrather than inhibition accuracy; and, second, we observed a negative correlationbetween dependence severity and the modulation of the left FPN network by themonetary reward in ACD. These findings highlight the role of the left FPN in themotivational effects of cocaine dependence. [-]
Publicado en
Addiction biology, 2019Proyecto de investigación
Ministerio de Economía y Competitividad. Grant Number: PSI2012‐33054; Spanish National Drug Strategy Ministerio de Sanidad y Consumo. Grant Number: 040/2011Derechos de acceso
Copyright © John Wiley & Sons, Inc.
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