dc.contributor.author | Santas, Enrique | |
dc.contributor.author | Palau, Patricia | |
dc.contributor.author | Guazzi, Marco | |
dc.contributor.author | De la Espriella, Rafael | |
dc.contributor.author | Miñana, Gema | |
dc.contributor.author | Sanchis, Juan | |
dc.contributor.author | Bayes-Genis, Antoni | |
dc.contributor.author | Lupón, Josep | |
dc.contributor.author | Chorro, Francisco J. | |
dc.contributor.author | Núñez, Julio | |
dc.date.accessioned | 2019-07-23T07:32:23Z | |
dc.date.available | 2019-07-23T07:32:23Z | |
dc.date.issued | 2019 | |
dc.identifier.citation | SANTAS, Enrique, et al. Usefulness of Right Ventricular to Pulmonary Circulation Coupling as an Indicator of Risk for Recurrent Admissions in Heart Failure With Preserved Ejection Fraction. The American journal of cardiology, 2019. | ca_CA |
dc.identifier.issn | 0002-9149) | |
dc.identifier.uri | http://hdl.handle.net/10234/183333 | |
dc.description.abstract | In recent years, the study of right ventricular (RV) to pulmonary circulation (PC) coupling in heart failure with preserved ejection fraction (HFpEF) has been a matter of special interest. Tricuspid annular plane systolic excursion (TAPSE) to pulmonary artery systolic pressure (PASP) ratio has emerged as a reliable noninvasive index of RV to PC coupling. Thus, we hypothesized that TAPSE/PASP would be a predictor of readmission burden in HFpEF. One thousand one hundred and twenty seven consecutive HFpEF patients discharged for acute HF were included. In 367 patients (32.6%), PASP could not be accurately measured by echocardiography, leaving the final sample size to be 760 patients. Negative binomial regression method was used to evaluate the association between TAPSE/PASP ratio and recurrent admissions. Mean age of the cohort was 75.6 ± 9.7 years and 68.3% were women. At a median (interquartile range) follow-up of 2.0 (2.9) years, 352 (46.3%) patients died and 1,214 readmissions were registered in 482 patients (63.4%), being 506 of them HF-related. There was a stepwise increase in the rates of all-cause and HF readmissions by decreasing TAPSE/PASP ratio. After multivariable adjustment, TAPSE/PASP <0.36 was associated with a higher risk of HF-related recurrent admissions (incidence rate ratio [IRR] 1.51, 95% confidence interval [CI], 1.01 to 2.24; p = 0.040), whereas patients in the lowest quintile (TAPSE/PASP <0.28) exhibited the highest risk of both all-cause and HF-related recurrent admissions (IRR 1.40, 95% CI 1.04 to 1.87, p = 0.025; and IRR 1.85, 95% CI 1.22 to 2.80, p = 0.004, respectively). In conclusion, TAPSE/PASP ratio, as a noninvasive index of RV-PC coupling, emerges as a strong predictor of recurrent hospitalizations in HFpEF. | ca_CA |
dc.format.extent | 6 p. | ca_CA |
dc.language.iso | eng | ca_CA |
dc.publisher | Elsevier | ca_CA |
dc.relation.isPartOf | The American journal of cardiology, 2019 | ca_CA |
dc.rights | © Elsevier Inc. All rights reserved. | ca_CA |
dc.rights.uri | http://rightsstatements.org/vocab/InC/1.0/ | * |
dc.subject | right ventricula | ca_CA |
dc.subject | pulmonary circulation | ca_CA |
dc.subject | preserved ejection fraction | ca_CA |
dc.subject | systolic excursion | ca_CA |
dc.title | Usefulness of Right Ventricular to Pulmonary Circulation Coupling as an Indicator of Risk for Recurrent Admissions in Heart Failure With Preserved Ejection Fraction | ca_CA |
dc.type | info:eu-repo/semantics/article | ca_CA |
dc.identifier.doi | https://doi.org/10.1016/j.amjcard.2019.05.024 | |
dc.rights.accessRights | info:eu-repo/semantics/restrictedAccess | ca_CA |
dc.relation.publisherVersion | https://www.sciencedirect.com/science/article/pii/S0002914919305910 | ca_CA |
dc.type.version | info:eu-repo/semantics/publishedVersion | ca_CA |