• openAccess   Activation and friction in enzymatic loop opening and closing dynamics 

      Zinovjev, Kirill; Guénon, Paul; Ramos Guzmán, Carlos Alberto; Ruiz-Pernía, José Javier; Laage, Damien; Tuñón, Iñaki Springer Nature (2024-03-20)
      Protein loop dynamics have recently been recognized as central to enzymatic activity, specificity and stability. However, the factors controlling loop opening and closing kinetics have remained elusive. Here, we combine ...