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Engineering a Highly Regioselective Fungal Peroxygenase for the Synthesis of Hydroxy Fatty Acids
González-Benjumea, Alejandro; Gomez de Santos, Patricia; Fernández-García, Ángela; Aranda Oliden, María del Carmen; Wu, Yinqi; But, Andrada; Molina-Espeja, Patricia; Mate, Diana; Gonzalez-Perez, David; Zhang, Wuyuan; Kiebist, Jan; Scheibner, Katrin; Hofrichter, Martin; Świderek, Katarzyna; Moliner, Vicent; Sanz-Aparicio, Julia; Hollmann, Frank; Gutiérrez, Ana; Alcalde, Miguel John Wiley & Sons (2023-02-20)The hydroxylation of fatty acids is an appealing reaction in synthetic chemistry, although the lack of selective catalysts hampers its industrial implementation. In this study, we have engineered a highly regioselective ...