ListarInstitute of Advanced Materials (INAM) por tema "enzyme mechanisms"

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    • openAccess   Activation and friction in enzymatic loop opening and closing dynamics 

      Zinovjev, Kirill; Guénon, Paul; Ramos Guzmán, Carlos Alberto; Ruiz-Pernía, José Javier; Laage, Damien; Tuñón, Iñaki Springer Nature (2024-03-20)
      Protein loop dynamics have recently been recognized as central to enzymatic activity, specificity and stability. However, the factors controlling loop opening and closing kinetics have remained elusive. Here, we combine ...

    • openAccess   Mechanistic studies of a lipase unveil effect of pH on hydrolysis products of small PET modules 

      Świderek, Katarzyna; Velasco-Lozano, Susana; Galmés, Miquel À; Olazabal, Ion; Sardon, Haritz; López Gallego, Fernando; Moliner, Vicent Springer Nature (2023-06-15)
      Biocatalysis is a key technology enabling plastic recycling. However, despite advances done in the development of plastic-degrading enzymes, the molecular mechanisms that govern their catalytic performance are poorly ...