Listar LSI_Congressos i conferències por autoría "9d684c81-d372-4483-b53f-092847f5a5a2"
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Crosstalk between smoking and the genome in older subjects with metabolic syndrome through genomics, epigenomics and transcriptomics
Coltell, Oscar; Asensio, Eva Maria; CAROLINA, ORTEGA-AZORÍN; Barragán-Arnal, Rocío; Sáiz, Carmen; Portolés, Olga; Sorlí, José V; Corella, Dolores European Molecular Biology Organization (EMBO) (2019-09-11)Tobacco smoking (Figure 1) is a major cause of cardiovascular diseases (CVD), and appears to have a multiplicative interaction with the other major CVD risk factors (lipids, hypertension, diabetes and others present in the ... -
Genome-wide association analyses of weight loss in a randomized controlled trial of lifestyle intervention, and combined transcriptome-wide associations in a Mediterranean population
Corella, Dolores; Asensio, Eva Maria; CAROLINA, ORTEGA-AZORÍN; Sorlí, José V; Fernández-Carrión, Rebeca; Barragán-Arnal, Rocío; González, José I.; Coltell, Oscar European Molecular Biology Organization (EMBO) (2019-09-11)Although large-scale genome-wide association studies (GWAS) for obesity traits have identified more than 400 associated loci from observational studies (Figure 1), we highlight the fact that currently the number of GWAS ... -
Influence of the adherence to the Mediterranean diet on the effect of smoking on genomewide methylation among subjects with metabolic syndrome
Coltell, Oscar; Asensio, Eva Maria; CAROLINA, ORTEGA-AZORÍN; Sorlí, José V; González-Monje, Inma; Pascual, Eva C.; Portolés, Olga; Sáiz, Carmen; Corella, Dolores Heart Centre, University Hospital Halle (Saale) (2019-09-13)Tobacco smoking is an important risk factor for lung cancer, respiratory diseases and cardiovascular diseases, among others. Moreover, smoking can speed up the normal aging process of several tissues increasing the biological ... -
Metabolites, genomics, epigenomics, exposomics and health: Focus on serum bilirubin concentrations in subjects with metabolic syndrome from a Mediterranean population
Coltell, Oscar; Asensio, Eva Maria; Barragán-Arnal, Rocío; Sorlí, José V; Corella, Dolores Gordon Research Conferences (2019-02-03)Although metabolomics aims at the measurement of small molecules (metabolites) in a biological sample, this knowledge requires additional information on the related genetic variants, epigenetic regulators and environmental ... -
The Gln241His polymorphism in the carbohydrate response element binding protein (MLXIPL) gene
CAROLINA, ORTEGA-AZORÍN; Carrasco, Paula; Sorlí, José V; Coltell, Oscar; Asensio, Eva Maria; Luna, C.; González, José I.; Corella, Dolores Nature Publishing Group (2009-06) -
Untargeted metabolomics based on ultra-high-performance liquid chromatography-ion mobility-quadrupole time-of-flight mass spectrometry for biomarker discovery of orange intake in a cross-over trial
Portoles, Tania; Coltell, Oscar; Lacalle-Bergeron, Leticia; Sancho, Juan V; Lopez, Francisco; CAROLINA, ORTEGA-AZORÍN; Asensio, Eva Maria; Corella, Dolores Gordon Research Conferences (2019-02-03)Diet is one of the most important lifestyle factors associated with health status. Currently, one of the main limitations of nutritional epidemiology and nutritional genomics is the difficulty in the measurements of dietary ...