Listar UJI: Investigación por autoría "8a792e4b-875c-4b49-b773-9351f1ba53bb"
Mostrando ítems 1-6 de 6
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A Critical Period for Prefrontal Network Configurations Underlying Psychiatric Disorders and Addiction
Guirado, Ramón; Perez-Rando, Marta; Ferragud, Antonio; Gutiérrez-Castellanos, Nicolás; Umemori, Juzoh; Carceller, Héctor; Nacher, Juan; Castillo-Gomez, Esther Frontiers Media (2020-04-07)The medial prefrontal cortex (mPFC) has been classically defined as the brain region responsible for higher cognitive functions, including the decision-making process. Ample information has been gathered during the last ... -
Automated analysis of images for molecular quantification in immunohistochemistry
Guirado, Ramón; Carceller, Héctor; Castillo-Gomez, Esther; Castrén, Eero; Nacher, Juan Elsevier (2018-06)The quantification of the expression of different molecules is a key question in both basic and applied sciences. While protein quantification through molecular techniques leads to the loss of spatial information and ... -
Effects of Dopamine on the Immature Neurons of the Adult Rat Piriform Cortex
Coviello, Simona; Montes Cebrián, Yaiza; Castillo-Gómez, Esther; Nacher, Juan Frontiers Media (2020-10-06)The layer II of the adult piriform cortex (PCX) contains a numerous population of immature neurons. Interestingly, in both mice and rats, most, if not all, these cells have an embryonic origin. Moreover, recent studies ... -
Lack of MeCP2 leads to region-specific increase of doublecortin in the olfactory system
Martínez-Rodríguez, Elena; Martín Sánchez, Ana; Coviello, Simona; Foiani, Cristina; Kul, Emre; Martinez-Garcia, Fernando; Nacher, Juan; Lanuza, Enrique; Santos, Mónica; Agustín-Pavón, Carmen Springer (2019-05)The protein doublecortin is mainly expressed in migrating neuroblasts and immature neurons. The X-linked gene MECP2, associated to several neurodevelopmental disorders such as Rett syndrome, encodes the protein methyl-CpG-binding ... -
Long term effects of peripubertal stress on excitatory and inhibitory circuits in the prefrontal cortex of male and female mice
BUENO FERNANDEZ, CLARA; Perez-Rando, Marta; Alcaide, Julia; Coviello, Simona; Sandi, Carmen; Castillo-Gómez, Esther; Nacher, Juan Elsevier ScienceDirect (2021-04-01)The impact of stressful events is especially important during early life, because certain cortical regions, especially the prefrontal cortex (PFC), are still developing. Consequently, aversive experiences that occur during ... -
The TrkB agonist 7,8-dihydroxyflavone changes the structural dynamics of neocortical pyramidal neurons and improves object recognition in mice
Perez-Rando, Marta; Castillo-Gomez, Esther; Bueno-Fernández, Clara; Nacher, Juan Springer Verlag (2018-06)BDNF and its receptor TrkB have important roles in neurodevelopment, neural plasticity, learning, and memory. Alterations in TrkB expression have been described in different CNS disorders. Therefore, drugs interacting with ...