Octodon degus: A Model for the Cognitive Impairment Associated with Alzheimer's Disease
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Altres documents de l'autoria: Tarragon Cros, Ernesto; López, Dolores; Estrada, Cristina; Schenker, Esther; Bordet, Regis; Richardson, Jill C.; Herrero Ezquerro, María Trinidad; González Cuello, Ana
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Títol
Octodon degus: A Model for the Cognitive Impairment Associated with Alzheimer's DiseaseAutoria
Data de publicació
2013-05-27Editor
WileyISSN
1755-5930; 1755-5949Cita bibliogràfica
TARRAGON, Ernesto, et al. Octodon degus: A Model for the Cognitive Impairment Associated with Alzheimer's Disease. CNS neuroscience & therapeutics, 2013, vol. 19, no 9, p. 643-648Tipus de document
info:eu-repo/semantics/articleVersió de l'editorial
http://onlinelibrary.wiley.com/doi/10.1111/cns.12125/abstractVersió
info:eu-repo/semantics/sumittedVersionParaules clau / Matèries
Resum
Octodon degus (O. degus) is a diurnal rodent that spontaneously develops several physiopathological conditions, analogous in many cases to those experienced by humans. In light of this, O. degus has recently been ... [+]
Octodon degus (O. degus) is a diurnal rodent that spontaneously develops several physiopathological conditions, analogous in many cases to those experienced by humans. In light of this, O. degus has recently been identified as a very valuable animal model for research in several medical fields, especially those concerned with neurodegenerative diseases in which risk is associated with ageing. O. degus spontaneously develops β-amyloid deposits analogous to those observed in some cases of Alzheimer’s disease (AD). Moreover, these deposits are thought to be the key feature for AD diagnosis, and one of the suggested causes of cell loss and cognitive deficit. This review aims to bring together information to support O. degus as a valuable model for the study of cerebral aging. [-]
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CNS neuroscience & therapeutics, 2013, vol. 19, no 9Drets d'accés
© 2013 John Wiley & Sons Ltd
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