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Dopamine/adenosine interactions involved in effort-related aspects of food motivation
dc.contributor.author | Salamone, John | |
dc.contributor.author | Correa, Merce | |
dc.date.accessioned | 2012-08-07T09:56:05Z | |
dc.date.available | 2012-08-07T09:56:05Z | |
dc.date.issued | 2009 | |
dc.identifier | http://dx.doi.org/10.1016/j.appet.2009.07.018 | |
dc.identifier.citation | Appetite, 53, 3, p. 422-425 | |
dc.identifier.issn | 1956663 | |
dc.identifier.uri | http://hdl.handle.net/10234/43755 | |
dc.description.abstract | Nucleus accumbens dopamine (DA) is involved in effort-related aspects of food motivation. Accumbens DA depletions reduce the tendency of rats to work for food, and alter effort-related choice, but leave other aspects of food motivation and appetite intact. DA and adenosine receptors interact to regulate effort-related processes. Adenosine A<sub>2A</sub> antagonists can reverse the effects of DA D<sub>2</sub> antagonists on effort-related choice, and intra-accumbens injections of a adenosine A<sub>2A</sub> agonist produce effects that are similar to those produced by accumbens DA depletion or antagonism. These studies have implications for understanding the neurochemical interactions that underlie activational aspects of motivation. © 2009 Elsevier Ltd. All rights reserved. | |
dc.language.iso | eng | |
dc.publisher | Elsevier | |
dc.rights.uri | http://rightsstatements.org/vocab/CNE/1.0/ | * |
dc.subject | Activation | |
dc.subject | Behavioral economics | |
dc.subject | Decision making | |
dc.subject | Motivation | |
dc.subject | Operant | |
dc.subject | Reinforcement | |
dc.subject | Reward | |
dc.title | Dopamine/adenosine interactions involved in effort-related aspects of food motivation | |
dc.type | info:eu-repo/semantics/article | |
dc.identifier.doi | http://dx.doi.org/10.1016/j.appet.2009.07.018 | |
dc.rights.accessRights | info:eu-repo/semantics/restrictedAccess | |
dc.type.version | info:eu-repo/semantics/publishedVersion | ca_CA |
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