Neural activity patterns in the chemosensory network encoding vomeronasal and olfactory information in mice
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Otros documentos de la autoría: Pardo-Bellver, Cecília; Vila Martín, Manuel Esteban; Martínez-Bellver, Sergio; Faus, María Villafranca
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Título
Neural activity patterns in the chemosensory network encoding vomeronasal and olfactory information in miceAutoría
Fecha de publicación
2022Editor
Frontiers MediaISSN
1662-5129Cita bibliográfica
Pardo-Bellver C, Vila-Martin ME, Martínez-Bellver S, Villafranca-Faus M, Teruel-Sanchis A, Savarelli-Balsamo CA, Drabik SM, Martínez-Ricós J, Cervera-Ferri A, Martínez-García F, Lanuza E and Teruel-Martí V (2022) Neural activity patterns in the chemosensory network encoding vomeronasal and olfactory information in mice. Front. Neuroanat. 16:988015. doi: 10.3389/fnana.2022.988015Tipo de documento
info:eu-repo/semantics/articleVersión
info:eu-repo/semantics/publishedVersionPalabras clave / Materias
Resumen
Rodents detect chemical information mainly through the olfactory and
vomeronasal systems, which play complementary roles to orchestrate
appropriate behavioral responses. To characterize the integration of
chemosensory ... [+]
Rodents detect chemical information mainly through the olfactory and
vomeronasal systems, which play complementary roles to orchestrate
appropriate behavioral responses. To characterize the integration of
chemosensory information, we have performed electrophysiological and
c-Fos studies of the bulbo–amygdalar network in freely behaving female
mice exploring neutral or conspecific stimuli. We hypothesize that processing
conspecifics stimuli requires both chemosensory systems, and thus our results
will show shared patterns of activity in olfactory and vomeronasal structures.
Were the hypothesis not true, the activity of the vomeronasal structures
would be independent of that of the main olfactory system. In the c-Fos
analysis, we assessed the activation elicited by neutral olfactory or male stimuli
in a broader network. Male urine induced a significantly higher activity in
the vomeronasal system compared to that induced by a neutral odorant.
Concerning the olfactory system, only the cortex–amygdala transition area
showed significant activation. No differential c-Fos expression was found in
the reward system and the basolateral amygdala. These functional patterns in
the chemosensory circuitry reveal a strong top-down control of the amygdala
over both olfactory bulbs, suggesting an active role of the amygdala in the
integration of chemosensory information directing the activity of the bulbs
during environmental exploration. [-]
Publicado en
Frontiers in Neuroanatomy 16:988015Entidad financiadora
Agencia Estatal de Investigación of the Ministerio de Ciencia e Innovación | Spanish Ministry of Education of Spain | University of Valencia
Código del proyecto o subvención
PID2019-108562GB-I00/AEI/10.13039/501100011033 | FPU20/02632 | PREDOC19F1-1006157 | PREDOC19F1-1010260 | PREDOC20-1345866
Derechos de acceso
info:eu-repo/semantics/openAccess
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