The Association between a MAOB Variable Number Tandem Repeat Polymorphism and Cocaine and Opiate Addictions in Polyconsumers
Ver/ Abrir
Impacto
Scholar |
Otros documentos de la autoría: Mateu, Cesar; Rodríguez-Arias, Marta; Gil-Miravet, Isis; Benito, Ana; Tomas, Jose Manuel; Haro, Gonzalo
Metadatos
Mostrar el registro completo del ítemcomunitat-uji-handle:10234/9
comunitat-uji-handle2:10234/36080
comunitat-uji-handle3:10234/36082
comunitat-uji-handle4:
INVESTIGACIONMetadatos
Título
The Association between a MAOB Variable Number Tandem Repeat Polymorphism and Cocaine and Opiate Addictions in PolyconsumersAutoría
Fecha de publicación
2021-10Editor
MDPIISSN
2076-3425Cita bibliográfica
Mateu, C.; Rodríguez-Arias, M.; Gil-Miravet, I.; Benito, A.; Tomás, J.M.; Haro, G. The Association between a MAOB Variable Number Tandem Repeat Polymorphism and Cocaine and Opiate Addictions in Polyconsumers. Brain Sci. 2021, 11, 1265. https://doi.org/10.3390/brainsci11101265Tipo de documento
info:eu-repo/semantics/articleVersión de la editorial
https://www.mdpi.com/2076-3425/11/10/1265Versión
info:eu-repo/semantics/publishedVersionPalabras clave / Materias
Descripción
Genetic analysis of the association between alcohol, cocaine, and opiate addiction and variable number tandem repeat (VNTR) polymorphisms in monoamine oxidase B (MAOB) and serotonergic 5-hydroxytryptamine (serotonin) ... [+]
Genetic analysis of the association between alcohol, cocaine, and opiate addiction and variable number tandem repeat (VNTR) polymorphisms in monoamine oxidase B (MAOB) and serotonergic 5-hydroxytryptamine (serotonin) receptor 1B and 2C (HTR1B 21 and HTR2C) pathway genes was performed in a sample of 302 polyconsumers. Our genetic association analysis revealed a significant association between a 184 base pair (bp) VNTR polymorphism in the MAOB gene and addiction to cocaine and opiates. This work highlights new genetic marker associations in cocaine and opiate polyconsumer addictions. These data help to clarify and quantify the complex role of genetics in addictive disorders, as well as their future contribution to the prevention (genetic counselling), diagnosis (genetic diagnosis of vulnerability), and treatment (pharmacogenomics) of these disorders. [-]
Publicado en
Brain Sciences, 2021, vol. 11, no 10Entidad financiadora
Centro Superior de Investigación en Salud Pública (CSISP) | Generalitat Valenciana | Research Foundation of the Hospital Provincial de Castellón
Código del proyecto o subvención
CS2003-05-05 | T4591000 | CAF 15-049 | CAF 21-026
Derechos de acceso
info:eu-repo/semantics/openAccess
Aparece en las colecciones
- MED_Articles [641]
Excepto si se señala otra cosa, la licencia del ítem se describe como: Copyright: © 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).