Travelling wave ion mobility-derived collision cross section for mycotoxins: Investigating interlaboratory and interplatform reproducibility
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Otros documentos de la autoría: Righetti, Laura; Dreolin, Nicola; Celma, Alberto; mccullagh, mike; Barknowitz, Gitte; Sancho, Juan V; Dall’Asta, Chiara
Metadatos
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INVESTIGACIONMetadatos
Título
Travelling wave ion mobility-derived collision cross section for mycotoxins: Investigating interlaboratory and interplatform reproducibilityAutoría
Fecha de publicación
2020-09-01Editor
American Chemical SocietyISSN
0021-8561Cita bibliográfica
RIGHETTI, Laura, et al. Travelling Wave Ion Mobility-Derived Collision Cross Section for Mycotoxins: Investigating Interlaboratory and Interplatform Reproducibility. Journal of Agricultural and Food Chemistry, 2020, vol. 68, no 39, p. 10937-10943.Tipo de documento
info:eu-repo/semantics/articleVersión de la editorial
https://pubs.acs.org/doi/10.1021/acs.jafc.0c04498Versión
info:eu-repo/semantics/acceptedVersionPalabras clave / Materias
Resumen
Parent and modified mycotoxin analysis remains a challenge because of their chemical diversity, the presence of
isomeric forms, and the lack of analytical standards. The creation and application of a collision cross ... [+]
Parent and modified mycotoxin analysis remains a challenge because of their chemical diversity, the presence of
isomeric forms, and the lack of analytical standards. The creation and application of a collision cross section (CCS) database for
mycotoxins may bring new opportunities to overcome these analytical challenges. However, it is still an open question whether
common CCS databases can be used independently from the instrument type and ion mobility mass spectrometry (IM-MS)
technologies, which utilize different methodologies for determining the gas-phase mobility. Here, we demonstrated the
reproducibility of CCS measurements for mycotoxins in an interlaboratory study (average RSD 0.14% ± 0.079) and across different
traveling wave IM-MS (TWIMS) systems commercially available (ΔCCS% < 2). The separation in the drift time dimension of
critical pairs of isomers for modified mycotoxins was also achieved. In addition, the comparison of measured and predicted CCS
values, including regulated and emerging mycotoxins, was addressed. [-]
Publicado en
J. Agric. Food Chem. 2020, 68, 39, 10937–10943Proyecto de investigación
BES-2016-076914Derechos de acceso
© 2020 American Chemical Society
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