Renal function and attributable risk of death and cardiovascular hospitalization in participants with diabetes from a registry-based cohort
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Scholar |
Otros documentos de la autoría: Ruiz-Quinteroa, Manuel; Redón, Josep; Téllez-Plaza, María; Cebrián-Cuenca, Ana María; Navarro Pérez, Jorge; Menéndez, Edelmiro; Pérez Navarro, Ana M.; Fernández Giménez, Antonio; López Pineda, Adriana; QUESADA, JOSE ANTONIO; Pallarés-Carratalá, Vicente; Gil-Guillén, Vicente F; Moreno, Jose; Bleda-Cano, Jesús; Carrascosa, Sara; Carratalá Munuera, Concepción
Metadatos
Mostrar el registro completo del ítemcomunitat-uji-handle:10234/9
comunitat-uji-handle2:10234/36080
comunitat-uji-handle3:10234/36082
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https://doi.org/10.1016/j.pcd.2020.06.004 |
Metadatos
Título
Renal function and attributable risk of death and cardiovascular hospitalization in participants with diabetes from a registry-based cohortAutoría
Fecha de publicación
2020Editor
ElsevierISSN
1751-9918Cita bibliográfica
M. Ruiz-Quintero, et al., Renal function and attributable risk of death and cardiovascular hospitalization in participants with diabetes from a registry-based cohort, Primary Care Diabetes. (2020), https://doi.org/10.1016/j.pcd.2020.06.004Tipo de documento
info:eu-repo/semantics/articleVersión de la editorial
https://www.sciencedirect.com/science/article/pii/S1751991820302163Versión
info:eu-repo/semantics/publishedVersionPalabras clave / Materias
Resumen
Aims
To estimate the attributable risk of renal function on all-cause mortality and cardiovascular hospitalization in patients with diabetes.
Methods
A prospective cohort study in 19,469 adults with diabetes, ... [+]
Aims
To estimate the attributable risk of renal function on all-cause mortality and cardiovascular hospitalization in patients with diabetes.
Methods
A prospective cohort study in 19,469 adults with diabetes, free of cardiovascular disease, attending primary care in Spain (2008–2011). The estimated glomerular filtration rate (eGFR) and other variables were collected and patients were followed to the first hospitalization for coronary or stroke event, or death, until the end of 2012. The cumulative incidence of the study endpoints by eGFR categories was graphically displayed and adjusted population attributable risks (PARs) for low eGFR was calculated.
Results
Mean follow-up was 3.2 years and 506 deaths and 1720 hospitalizations were recorded. The cumulative risk for the individual events increased as eGFR levels decreased. The PAR associated with having an eGFR of 60 mL/min/1.73 m2 or less was 11.4% (95% CI 4.8–18.3) for all-cause mortality, 9.2% (95% CI 5.3–13.4) for coronary heart disease, and 2.6% (95% CI −1.8 to 7.4) for stroke.
Conclusions
Reduced eGFR levels were associated with a larger proportion of avoidable deaths and cardiovascular hospitalizations in people with diabetes compared to previously reported results in people with other cardiovascular risk factors. [-]
Publicado en
Primary Care DiabetesDerechos de acceso
©
2020
Primary
Care
Diabetes
Europe.
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by
Elsevier
Ltd.
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reserved.
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