Three-Step Telescoped Synthesis of Monosubstituted Vicinal Diamines from Aldehydes
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Other documents of the author: Bou Iserte, Lledó; Latorre, Antonio; Rodríguez, Santiago; González, Florenci
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Title
Three-Step Telescoped Synthesis of Monosubstituted Vicinal Diamines from AldehydesDate
2019ISSN
2470-1343Bibliographic citation
BOU-ISERTE, Lledó, et al. Three-Step Telescoped Synthesis of Monosubstituted Vicinal Diamines from Aldehydes. ACS Omega, 2019, vol. 4, no 1, p. 2261-2267Type
info:eu-repo/semantics/articlePublisher version
https://pubs.acs.org/doi/full/10.1021/acsomega.8b03030Version
info:eu-repo/semantics/publishedVersionAbstract
Aldehydes are easily transformed into vicinal diamines and piperazines through a one-pot procedure including a Darzens reaction and treatment with an amine or diamine and then with a reducing agent. Additionally, ... [+]
Aldehydes are easily transformed into vicinal diamines and piperazines through a one-pot procedure including a Darzens reaction and treatment with an amine or diamine and then with a reducing agent. Additionally, quinoxalines can be accessed by reaction with 1,2-benzenediamine under oxidative conditions. These transformations are simple methods for the preparation of synthetically interesting monosubstituted diamines, piperazines, and quinoxalines. [-]
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ACS Omega, 2019, vol. 4, no 1Investigation project
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