Probiotics in digestive, emotional, and pain-related disorders
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Otros documentos de la autoría: Roman, Pablo; Abalo, Raquel; Marco, Eva, M.; Cardona, Diana
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Probiotics in digestive, emotional, and pain-related disordersFecha de publicación
2018-04Editor
Lippincott, Williams & WilkinsCita bibliográfica
ROMAN, Pablo, et al. Probiotics in digestive, emotional, and pain-related disorders. Behavioural Pharmacology, 2018, vol. 29, no 2 and 3-Special Issue, p. 103-119Tipo de documento
info:eu-repo/semantics/articleVersión de la editorial
https://journals.lww.com/behaviouralpharm/Abstract/2018/04000/Probiotics_in_dige ...Versión
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Resumen
In recent years, interest in the relationship between gut microbiota and disease states has grown considerably. Indeed, several strategies have been employed to modify the microbiome through the administration of ... [+]
In recent years, interest in the relationship between gut microbiota and disease states has grown considerably. Indeed, several strategies have been employed to modify the microbiome through the administration of different diets, by the administration of antibiotics or probiotics, or even by transplantation of feces. In the present manuscript, we focus specifically on the potential application of probiotics, which seem to be a safe strategy, in the management of digestive, pain, and emotional disorders. We present evidence from animal models and human studies, notwithstanding that translation to clinic still deserves further investigation. The microbiome influences gut functions as well as neurological activity by a variety of mechanisms, which are also discussed. The design and performance of larger trials is urgently needed to verify whether these new strategies might be useful not only for the treatment of disorders affecting the gastrointestinal tract but also in the management of emotional and pain disorders not directly related to the gut. [-]
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Behavioural Pharmacology, 2018, vol. 29, no 2 and 3-Special IssueDerechos de acceso
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