A Pilot Randomized Controlled Trial to Explore Cognitive and Emotional Effects of Probiotics in Fibromyalgia
Impacto
Scholar |
Otros documentos de la autoría: Roman, Pablo; Estévez, Ángeles F.; Miras, Alonso; Sánchez Labraca, María Nuria; Cañadas, Fernando; Vivas, Ana B.; Cardona, Diana
Metadatos
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INVESTIGACIONMetadatos
Título
A Pilot Randomized Controlled Trial to Explore Cognitive and Emotional Effects of Probiotics in FibromyalgiaAutoría
Fecha de publicación
2018-07Editor
Springer NatureCita bibliográfica
ROMAN, Pablo, et al. A Pilot Randomized Controlled Trial to Explore Cognitive and Emotional Effects of Probiotics in Fibromyalgia. Scientific reports, 2018, 8: 10965.Tipo de documento
info:eu-repo/semantics/articleVersión de la editorial
https://www.nature.com/articles/s41598-018-29388-5#Abs1Versión
info:eu-repo/semantics/publishedVersionPalabras clave / Materias
Resumen
It has recently been found that microbes in the gut may regulate brain processes through the gut microbiota–brain axis, which modulates affection, motivation and higher cognitive functions. According to this finding, ... [+]
It has recently been found that microbes in the gut may regulate brain processes through the gut microbiota–brain axis, which modulates affection, motivation and higher cognitive functions. According to this finding, the use of probiotics may be a potential treatment to improve physical, psychological and cognitive status in clinical populations with altered microbiota balance such as those with fibromyalgia (FMS). Thus, the aim of the present pilot study with a double-blind, placebo-controlled, randomised design was to test whether a multispecies probiotic may improve cognition, emotional symptoms and functional state in a sample of patients diagnosed with FMS. Pain, impact of FMS, quality of life, anxiety and depressive symptoms were measured during the pre- and post-intervention phases; participants also completed two computerised cognitive tasks to assess impulsive choice and decision-making. Finally, urinary cortisol concentration was determined. To our knowledge, this is the first study that explore the effect of a multispecies probiotic in FMS patients. Our results indicated that probiotics improved impulsivity and decision-making in these patients. However, more research is needed to further explore the potential effects of probiotics on other cognitive functions affected in FMS as well as in other clinical populations. [-]
Proyecto de investigación
Spanish Ministry of Economy and Competitiveness and the ERDF funds (Grant PSI2012-39228)Derechos de acceso
info:eu-repo/semantics/openAccess
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