Energy transduction and signal averaging of fluctuating electric fields by a single protein ion channel
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Other documents of the author: Verdiá Báguena, Carmen; Gómez, V.; Cervera, Javier; Ramírez, Patricio; Mafe, Salvador
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Show full item recordcomunitat-uji-handle:10234/9
comunitat-uji-handle2:10234/2507
comunitat-uji-handle3:10234/6973
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Title
Energy transduction and signal averaging of fluctuating electric fields by a single protein ion channelDate
2017Publisher
Royal Society of ChemistryISSN
1463-9076; 1463-9084Bibliographic citation
Phys. Chem. Chem. Phys., 2017, 19, 292Type
info:eu-repo/semantics/articleVersion
info:eu-repo/semantics/acceptedVersionAbstract
We demonstrate the electrical rectification and signal averaging of fluctuating signals using a biological
nanostructure in aqueous solution: a single protein ion channel inserted in the lipid bilayer characteristic
of ... [+]
We demonstrate the electrical rectification and signal averaging of fluctuating signals using a biological
nanostructure in aqueous solution: a single protein ion channel inserted in the lipid bilayer characteristic
of cell membranes. The conversion of oscillating, zero time-average potentials into directional currents
permits charging of a load capacitor to significant steady-state voltages within a few minutes in the case
of the outer membrane porin F (OmpF) protein, a bacterial channel of Escherichia coli. The experiments
and simulations show signal averaging effects at a more fundamental level than the traditional cell and
tissue scales, which are characterized by ensembles of many ion channels operating simultaneously. The
results also suggest signal transduction schemes with bio-electronic interfaces and ionic circuits where
soft matter nanodiodes can be coupled to conventional electronic elements. [-]
Is part of
Phys. Chem. Chem. Phys., 2017, 19Investigation project
MAT2015- 65011-P ; Prometeo/GV/ 0069Rights
http://rightsstatements.org/vocab/CNE/1.0/
info:eu-repo/semantics/openAccess
info:eu-repo/semantics/openAccess
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