Effects of Curcuminoid Pyrazoles on Cancer Cells and on the Expression of Telomerase Related Genes
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Otros documentos de la autoría: Martí-Centelles, Rosa; Falomir, Eva; Carda, Miguel; Nieto, Carla I.; Cornago, M. Pilar; Claramunt, Rosa M.
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http://dx.doi.org/10.1002/ardp.201600067 |
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Título
Effects of Curcuminoid Pyrazoles on Cancer Cells and on the Expression of Telomerase Related GenesAutoría
Fecha de publicación
2016-07Editor
WileyCita bibliográfica
MARTÍ‐CENTELLES, Rosa, et al. Effects of Curcuminoid Pyrazoles on Cancer Cells and on the Expression of Telomerase Related Genes. Archiv der Pharmazie, Volume 349, Issue 7, July 2016, pages 532–538.Tipo de documento
info:eu-repo/semantics/articleVersión de la editorial
http://onlinelibrary.wiley.com/doi/10.1002/ardp.201600067/fullPalabras clave / Materias
Resumen
A group of 13 curcuminoid pyrazoles was investigated for their cytotoxicity on three tumoral cell lines (HT-29, MCF-7, and HeLa) and one non-tumoral human cell line (HEK-293). The values obtained were compared with ... [+]
A group of 13 curcuminoid pyrazoles was investigated for their cytotoxicity on three tumoral cell lines (HT-29, MCF-7, and HeLa) and one non-tumoral human cell line (HEK-293). The values obtained were compared with those of curcumin. A subset of selected derivatives was also studied for their ability to downregulate expression of the hTERT and c-Myc genes, which are both involved in telomerase activity. [-]
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Archiv der Pharmazie Volume 349, Issue 7, July 2016Derechos de acceso
© 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
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