Effects of Curcuminoid Pyrazoles on Cancer Cells and on the Expression of Telomerase Related Genes
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Other documents of the author: Martí-Centelles, Rosa; Falomir, Eva; Carda, Miguel; Nieto, Carla I.; Cornago, M. Pilar; Claramunt, Rosa M.
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comunitat-uji-handle2:10234/7053
comunitat-uji-handle3:10234/8639
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http://dx.doi.org/10.1002/ardp.201600067 |
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Title
Effects of Curcuminoid Pyrazoles on Cancer Cells and on the Expression of Telomerase Related GenesAuthor (s)
Date
2016-07Publisher
WileyBibliographic citation
MARTÍ‐CENTELLES, Rosa, et al. Effects of Curcuminoid Pyrazoles on Cancer Cells and on the Expression of Telomerase Related Genes. Archiv der Pharmazie, Volume 349, Issue 7, July 2016, pages 532–538.Type
info:eu-repo/semantics/articlePublisher version
http://onlinelibrary.wiley.com/doi/10.1002/ardp.201600067/fullSubject
Abstract
A group of 13 curcuminoid pyrazoles was investigated for their cytotoxicity on three tumoral cell lines (HT-29, MCF-7, and HeLa) and one non-tumoral human cell line (HEK-293). The values obtained were compared with ... [+]
A group of 13 curcuminoid pyrazoles was investigated for their cytotoxicity on three tumoral cell lines (HT-29, MCF-7, and HeLa) and one non-tumoral human cell line (HEK-293). The values obtained were compared with those of curcumin. A subset of selected derivatives was also studied for their ability to downregulate expression of the hTERT and c-Myc genes, which are both involved in telomerase activity. [-]
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Archiv der Pharmazie Volume 349, Issue 7, July 2016Rights
© 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
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