dc.contributor.author | Singh, Nishant | |
dc.contributor.author | Conte, M. P. | |
dc.contributor.author | Ulijn, R. V. | |
dc.contributor.author | Miravet, Juan | |
dc.contributor.author | Escuder, Beatriu | |
dc.date.accessioned | 2016-06-08T12:27:17Z | |
dc.date.available | 2016-06-08T12:27:17Z | |
dc.date.issued | 2016 | |
dc.identifier.citation | SINGH, Nishant; CONTE, M. P.; ULIJN, R. V.; MIRAVET CELADES, Juan Felipe; ESCUDER GIL, Beatriu. Insight into the esterase like activity demonstrated by an imidazole appended self-assembling hydrogelator. Chemical Communications (2016), v. 51, n.67, pp. 13213-13216 | ca_CA |
dc.identifier.uri | http://hdl.handle.net/10234/160469 | |
dc.description.abstract | A low molecular weight hydrogelator with a covalently appended imidazole moiety is reported. Capable of percolating water in the pH range of 6 to 8, it proves to be an efficient catalyst upon self-assembly, showing Michaelis-Menten type kinetics. Activities at different pH values correlated with dramatic structural changes were observed. It can hydrolyse p-nitrophenyl acetate (pNPA) as well as inactivated esters, and L and D-phenylalanine methyl esters. The enhanced activity can be related to the conglomeration of catalytic groups upon aggregation resulting in their close proximity and the formation of hydrophobic pockets. | ca_CA |
dc.description.sponsorShip | This work was supported by the EU Marie Curie ITN-Smartnet and the Ministry of Economy and Competitiveness of Spain (Grant CTQ2012-37735). N.S. and M.P.C. thank EU for an ESR Marie Curie contract. | ca_CA |
dc.format.extent | 4 p. | ca_CA |
dc.format.mimetype | application/pdf | ca_CA |
dc.language.iso | eng | ca_CA |
dc.publisher | Royal Society of Chemistry | ca_CA |
dc.relation.isPartOf | Chemical Communications (2016), v. 51, n.67 | ca_CA |
dc.rights.uri | http://rightsstatements.org/vocab/CNE/1.0/ | * |
dc.subject | Low molecular weight hydrogelator | ca_CA |
dc.subject | Covalently appended imidazole moiety | ca_CA |
dc.subject | Catalysis | ca_CA |
dc.subject | Michaelis-Menten type kinetics | ca_CA |
dc.subject | pH values | ca_CA |
dc.subject | p-nitrophenyl acetate (pNPA) | ca_CA |
dc.subject | Hydrophobic pockets. | ca_CA |
dc.title | Insight into the esterase like activity demonstrated by an imidazole appended self-assembling hydrogelator | ca_CA |
dc.type | info:eu-repo/semantics/article | ca_CA |
dc.identifier.doi | http://dx.doi.org/10.1039/C5CC04281J | |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | ca_CA |
dc.relation.publisherVersion | http://pubs.rsc.org/en/Content/ArticleHtml/2015/CC/c5cc04281j | ca_CA |