Nitric oxide sensitive fluorescent polymeric hydrogels showing negligible interference by dehydroascorbic acid
Impacto
Scholar |
Otros documentos de la autoría: Fabregat Tena, Víctor; Izquierdo Arcusa, María Ángeles; Burguete, M. Isabel; Galindo, Francisco; Luis, Santiago V.
Metadatos
Mostrar el registro completo del ítemcomunitat-uji-handle:10234/9
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http://dx.doi.org/10.1016/j.eurpolymj.2014.03.027 |
Metadatos
Título
Nitric oxide sensitive fluorescent polymeric hydrogels showing negligible interference by dehydroascorbic acidAutoría
Fecha de publicación
2014Editor
ElsevierISSN
0014-3057Tipo de documento
info:eu-repo/semantics/articleVersión de la editorial
http://www.sciencedirect.com/science/article/pii/S0014305714001074Palabras clave / Materias
Resumen
A series of nitric oxide (NO) sensitive polymeric hydrogels have been synthesized and their properties described. The new materials are based on a poly(2-hydroxyethyl methacrylate) matrix entrapping the DAF-FM (4-am ... [+]
A series of nitric oxide (NO) sensitive polymeric hydrogels have been synthesized and their properties described. The new materials are based on a poly(2-hydroxyethyl methacrylate) matrix entrapping the DAF-FM (4-amino-5-methylamino-2′,7′-difluorofluorescein) fluorescent probe. Some of the developed materials show sensitivities in the range ca. 50–75 nM towards NO dissolved in aerated phosphate buffer (PBS), being nitrous anhydride the reactive species under such conditions. Remarkably, the sensitivity of the fluorescent polymers is not influenced by dehydroascorbic acid, a molecule of biological importance, which has been reported to be a common interfering species capable to react with well known probes for NO. [-]
Publicado en
European Polymer Journal, 2014, vol. 55Derechos de acceso
http://rightsstatements.org/vocab/CNE/1.0/
info:eu-repo/semantics/restrictedAccess
info:eu-repo/semantics/restrictedAccess
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