Acceleration of short and long DNA read mapping without loss of accuracy using suffix array
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Other documents of the author: Tárraga, Joaquín; Arnau, Vicente; Martínez Pérez, Héctor; Moreno, Raul; Cazorla, Diego; Salavert Torres, José; Blanquer Espert, Ignacio; Dopazo, Joaquín; Medina, Ignacio
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Show full item recordcomunitat-uji-handle:10234/9
comunitat-uji-handle2:10234/7036
comunitat-uji-handle3:10234/8620
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http://dx.doi.org/10.1093/bioinformatics/btu553 |
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Title
Acceleration of short and long DNA read mapping without loss of accuracy using suffix arrayAuthor (s)
Date
2014-08Publisher
Oxford University PressISSN
1367-4803; 1460-2059Type
info:eu-repo/semantics/articlePublisher version
http://bioinformatics.oxfordjournals.org/content/30/23/3396.fullSubject
Abstract
HPG Aligner applies suffix arrays for DNA read mapping. This implementation produces a highly sensitive and extremely fast mapping of DNA reads that scales up almost linearly with read length. The approach presented ... [+]
HPG Aligner applies suffix arrays for DNA read mapping. This implementation produces a highly sensitive and extremely fast mapping of DNA reads that scales up almost linearly with read length. The approach presented here is faster (over 20× for long reads) and more sensitive (over 98% in a wide range of read lengths) than the current state-of-the-art mappers. HPG Aligner is not only an optimal alternative for current sequencers but also the only solution available to cope with longer reads and growing throughputs produced by forthcoming sequencing technologies. [-]
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Bioinformatics (2014) 30 (23)Rights
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