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COVID-19: La Prevención de Riesgos Laborales en en sector sanitario
Universitat Jaume I (2020-07-15)A través de una revisión bibliográfica, se presentan y detallan los aspectos considerados más relevantes acerca de la enfermedad COVID-19, las medidas preventivas y de protección empleadas en el ámbito hospitalario y las ... -
Genetic Load of SARS-CoV-2 in Aerosols Collected in Operating Theaters
American Society for Microbiology (2022-09-14)After the outbreak of COVID-19, additional protocols have been established to prevent the transmission of the SARS-CoV-2 from the patient to the health personnel and vice versa in health care settings. However, in the case ... -
Relevance of Viroporin Ion Channel Activity on Viral Replication and Pathogenesis
MDPI (2015-07)Modification of host-cell ionic content is a significant issue for viruses, as several viral proteins displaying ion channel activity, named viroporins, have been identified. Viroporins interact with different cellular ... -
The impact of SARS-CoV-2 3CL protease mutations on nirmatrelvir inhibitory efficiency. Computational insights into potential resistance mechanisms
The Royal Society of Chemistry (2023-02-14)The use of antiviral drugs can promote the appearance of mutations in the target protein that increase the resistance of the virus to the treatment. This is also the case of nirmatrelvir, a covalent inhibitor of the 3CL ...