• openAccess   Synthesis and Biological Evaluation of Potential Oncoimmunomodulator Agents 

      Gil-Edo, Raquel; ESPEJO, SARA; Falomir, Eva; Carda, Miguel MDPI (2023-01-30)
      Fourteen triazole-scaffold derivatives were synthetized and biologically evaluated as potential oncoimmunomodultator agents by targeting both PD-L1 and c-Myc. First, the antiproliferative activity of these molecules on the ...
    • openAccess   Synthesis and Biological Evaluation of Small Molecules as Potential Anticancer Multitarget Agents 

      Pla López, Alberto; Castillo, Raquel; Cejudo Marín, Rocío; García Pedrero, Olaya; Bakir Laso, Mariam; Falomir, Eva; Miguel Carda MDPI (2022-06-24)
      Twenty-six triazole-based derivatives were designed for targeting both PD-L1 (programmed death receptor ligand 1) and VEGFR-2 (vascular endothelial growth factor receptor 2). These compounds were synthetized and biologically ...