Listar por tema "cocaine"
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¿Afecta la lesión dorsal del cerebelo posterior a la actividad neuronal del tálamo? ¿Los cambios de actividad están relacionados con la memoria condicionada inducida por cocaína?
Universitat Jaume I (2016-07-19)La adicción es un trastorno crónico del cerebro que se caracteriza por el consumo y la búsqueda compulsiva de la droga a pesar de sus consecuencias negativas. Los estudios previos indican que el cerebelo está implicado en ... -
Brain networks alterations in cocaine use and gambling disorders during emotion regulation
Akadémiai Kiadó (2022)Background: Cocaine use disorder (CUD) and gambling disorder (GD) share clinical features and neural alterations, including emotion regulation deficits and dysfunctional activation in related networks. However, they also ... -
Consumo de drogas proactivas en el embarazo
Universitat Jaume I (2021-06-18)Introducción: La edad reproductiva en las mujeres coincide temporalmente con el período de mayor prevalencia de consumo de drogas psicoactivas. Cualquier droga consumida por una mujer embarazada supone un gran riesgo ... -
Distance disintegration characterizes node-level topological dysfunctions in cocaine addiction
Wiley (2021-11)Previous investigations have used global graph theory measures in order to disentangle the complexity of the neural reorganizations occurring in cocaine use disorder (CUD). However, how these global topological alterations ... -
Effects of perineuronal nets degradation by ChABC on neuronal activity in the cerebellar cortex
Universitat Jaume I (2017-07-19)Introduction. One of the key mechanisms for the stabilization of synaptic changes is the formation of specific extracellular matrix structures surrounding several neuronal populations at the end of the brain development, ... -
Estudio del impacto del programa de administración de cocaína en la adquisición de memorias condicionadas asociadas a la droga
Universitat Jaume I (2017)Las drogas de abuso son potentes estímulos que actúan como reforzadores sobre los sistemas neutrales de memoria y aprendizaje. Tras el uso continuado de la droga, sus efectos se asocian a claves o estímulos contextuales ... -
From back to front: A functional model for the cerebellar modulation in the establishment of conditioned preferences for cocaine‐related cues
Wiley (2019)It is now increasingly clear that the cerebellum may modulate brain functions altered in drug addiction. We previously demonstrated that cocaine‐induced conditioned preference increased activity at the dorsal posterior ... -
Implicación de las claves contextuales en la expresión de hiperactividad condicionada de animales previamente sensibilizados a la cocaína
Universitat Jaume I (2016-07-20)La sensibilización es uno de los procesos que tienen lugar en el desarrollo de las adicciones. Pese a su naturaleza no asociativa, la expresión de la sensibilización está fuertemente ligada al control contextual. En el ... -
Left frontoparietal network activity is modulated by drug stimuli in cocaine addiction
Springer (2018-10)Cocaine addicts present reduced activity in the left frontoparietal network, a brain network associated with cognitive control, during the processing of non-drug reward related stimuli (Costumero et al., Addiction Biology ... -
Modulation of Chromatin Modification Facilitates Extinction of Cocaine-Induced Conditioned Place Preference
Elsevier (2010)Background: Recent evidence suggests that epigenetic mechanisms have an important role in the development of addictive behavior. However, little is known about the role of epigenetic mechanisms in the extinction of ... -
Neural correlates of cocaine-induced conditioned place preference in the posterior cerebellar cortex
Frontiers Media (2023)Introduction: Addictive drugs are potent neuropharmacological agents capable of inducing long-lasting changes in learning and memory neurocircuitry. With repeated use, contexts and cues associated with consumption can ... -
Papel del córtex prefrontal en la búsqueda compulsiva de cocaína
Universitat Jaume I (2017-06-20)La adicción es una enfermedad crónica del cerebro caracterizada por la búsqueda y consumo compulsivos de la droga y la recaída reincidente. El consumo repetido de sustancias adictivas, como la cocaína, puede dar lugar a ... -
Papel del prelímbico en la adquisición de la memoria de preferencia hacia estímulos asociados a la cocaína
Universitat Jaume I (2016)Introducción: Hallazgos previos sugieren que el desarrollo de la adicción a las drogas puede ser entendido en términos de interacción entre los mecanismos cerebrales de memoria pavloviana e instrumental que subyacen a la ... -
Particpación del sistema NE en la expresión de memorias condicionadas asociadas a la administración de cocaína
Universitat Jaume I (2014-07-23)It has been proposed that neuroadaptations underlying psychomotor sensitization induced by repeated administration of drugs of abuse are associated with pathological, excessive motivation toward drugs and drug-associated ... -
Putting forward a model for the role of the cerebellum in cocaine-induced pavlovian memory
Frontiers Media (2023)Substance Use Disorder (SUD) involves emotional, cognitive, and motivational dysfunction. Long-lasting molecular and structural changes in brain regions functionally and anatomically linked to the cerebellum, such as the ... -
Reduced activity in functional networks during reward processing is modulated by abstinence in cocaine addicts
Wiley (2017-03)Cocaine addiction is characterized by alterations in motivational and cognitive processes. Recent studies have shown that some alterations present in cocaine users may be related to the activity of large functional networks. ... -
Role of hippocampal NF-κB and GluN2B in the memory acquisition impairment of experiences gathered prior to cocaine administration in rats
Nature Research (2021-10-08)Cocaine can induce severe neurobehavioral changes, among others, the ones involved in learning and memory processes. It is known that during drug consumption, cocaine-associated memory and learning processes take place. ... -
Role of Perineuronal nets in the cerebellar cortex in cocaine-induced conditioned preference, extinction, and reinstatement
Elsevier Ltd (2022-08-17)Perineuronal nets (PNNs) are cartilage-like structures of extracellular matrix molecules that enwrap in a net-like manner the cell-body and proximal dendrites of special subsets of neurons. PNNs stabilize their incoming ... -
Spatio‐temporal assessment of illicit drug use at large scale: evidence from 7 years of international wastewater monitoring
Wiley (2020-01)Background and aims: Wastewater‐based epidemiology is an additional indicator of drug use that is gaining reliability to complement the current established panel of indicators. The aims of this study were to: (i) assess ...