• openAccess   Correlation between biological responses in vitro and in vivo to Ca-doped sol-gel coatings assessed using proteomic analysis 

      García-Arnáez, Iñaki; Romero-Gavilán, Francisco J; Cerqueira, Andreia; Elortza, Felix; Azkargorta, Mikel; Muñoz Guzón, Fernando; Mata Roig, Manuel; MARTIN DE LLANO, JOSE JAVIER; Suay, Julio; GURRUCHAGA, MARILO; Goñi, Isabel Elsevier (2022-10-21)
      Poor correlation between the results of in vitro testing and the subsequent in vivo experiments hinders the design of biomaterials. Thus, new characterisation methods are needed. This study used proteomic and histological ...
    • openAccess   Osseointegration mechanisms: a proteomic approach 

      Gomes, Nuno; Romero-Gavilán, Francisco J; García-Arnáez, Iñaki; Martinez Ramos, Cristina; Sánchez-Pérez, Ana María; Azkargorta, Mikel; Elortza, Felix; Martín de Llano, J.J.; GURRUCHAGA, MARILO; Goñi, Isabel; Suay, Julio Springer-Verlag (2018-03)
      The prime objectives in the development of biomaterials for dental applications are to improve the quality of osseointegration and to short the time needed to achieve it. Design of implants nowadays involves changes in ...
    • openAccess   Self-assembled multivalent (SAMul) ligand systems with enhanced stability in the presence of human serum 

      Tena Solsona, Marta; Marson, Domenico; Rodrigo, Ana C.; Bromfield, Stephen M.; Escuder, Beatriu; Miravet, Juan; Apostolova, Nadezda; Laurini, Erik; Pricl, Sabrina Royal Society of Chemistry (2019)
      Self-assembled cationic micelles are an attractive platform for binding biologically-relevant polyanions such as heparin. This has potential applications in coagulation control, where a synthetic heparin rescue agent could ...
    • openAccess   The effect of calcium–magnesium mixtures in sol–gel coatings on bone tissue regeneration 

      Cerqueira, Andreia; García-Arnáez, Iñaki; Muriach, Maria; Azkargorta, Mikel; Elortza, Felix; Izquierdo, Raúl; Romero-Gavilán, Francisco J; GURRUCHAGA, MARILO; Suay, Julio; Goñi, Isabel Royal Society of Chemistry (2022)
      Calcium and magnesium are two elements essential for bone structure and metabolism. However, their synergistic or competitive effects on bone regeneration are often overlooked during biomaterial development. We examined ...