Listar por tema "antiproliferative activity"

Mostrando ítems 1-3 de 3

    • openAccess   Aryl azoles based scaffolds for disrupting tumor microenvironment 

      Pla López, Alberto; Martinez-Colomina, Paula; Cañada-García, Laura; Fuertes-Monge, Laura; Orellana-Palacios, Jose C.; Valderrama-Martínez, Alejandro; Pérez Sosa, Marikena; Carda, Miguel; Falomir, Eva Elsevier (2023-11-15)
      Thirty-nine aryl azoles, thirteen triazoles and twenty-seven tetrazoles, have been synthetized and biologically evaluated to determine their activity as tumor microenvironment disruptors. Antiproliferative studies have ...

    • closedAccess   Arylpyridines, arylpyrimidines and related compounds as potential modulator agents of the VEGF, hTERT and c-Myc oncogenes 

      Martín Beltrán, Celia; Sanchez Peris, Maria; Conesa Milián, Laura; Falomir, Eva; Murga, Juan; Carda, Miguel; Alberto Marco, J. Elsevier (2019-03-01)
      Twenty-four derivatives structurally related to honokiol have been synthesized and biologically evaluated. IC50 values were determined towards the HT-29, MCF-7 and HEK-293 cell lines. Some of these derivatives exhibited ...

    • openAccess   Synthesis and Antiproliferative Activity of 3 and 7-Styrylcoumarins 

      Herrera-R, Angie; Castrillón, Wilson; Otero, Elver; Ruiz, Esneyder; Carda, Miguel; Agut, Raúl; Naranjo Preciado, Tonny; Moreno, Gustavo; Maldonado, María Elena; Cardona Galeano, Wilson Isidro Springer Verlag (2018)
      A series of styrylcoumarins were obtained via Mizoroki-Heck reactions between 3-bromo-4-methyl7-(octyloxy)-2H-chromen-2-one or 2-oxo-2H-chromen-7-yl trifluoromethanesulfonate and functionalized styrenes. The structures ...