Listar por tema "Mitochondria"

Mostrando ítems 1-3 de 3

    • closedAccess   ER stress in human hepatic cells treated with Efavirenz: Mitochondria again 

      Apostolova, Nadezda; Gómez Sucerquia, Leysa J.; Alegre, Fernando; Funes, Haryes A.; Víctor, Víctor M.; Barrachina Sancho, María Dolores; Blas García, Ana; Esplugues Mota, Juan V. Elsevier (2013-10)
      Background & Aims ER stress is associated with a growing number of liver diseases, including drug-induced hepatotoxicity. The non-nucleoside analogue reverse transcriptase inhibitor Efavirenz, a cornerstone of the ...

    • openAccess   Perspectives and Potential Applications of Mitochondria-Targeted Antioxidants in Cardiometabolic Diseases and Type 2 Diabetes 

      Rocha, Milagros; Apostolova, Nadezda; Herance, Jose Raul; Rovira Llopis, Susana; Hernández Mijares, Antonio; Víctor, Víctor M. John Wiley & Sons (2013)
      There is abundant evidence to suggest that mitochondrial dysfunction is a main cause of insulin resistance and related cardiometabolic comorbidities. On the other hand, insulin resistance is one of the main characteristics ...

    • closedAccess   Using exomarkers to assess mitochondrial reactive species in vivo 

      Logan, Angela; Cochemé, Helena M.; Boon Li Pun, Pamela; Apostolova, Nadezda; Smith, Robin A. J.; Larsen, Lesley; Larsen, David S.; James, Andrew M.; Fearnley, Ian M.; Rogatti, Sebastian; Prime, Tracy A.; Finichiu, Peter G.; Dare, Anna; Chouchani, Edward T.; Pell, Victoria R.; Methner, Carmen; Quin, Caroline; McQuaker, Stephen J.; Krieg, Thomas; Hartley, Richard C.; Murphy, Michael P. Elsevier (2014-02)
      Background The ability to measure the concentrations of small damaging and signalling molecules such as reactive oxygen species (ROS) in vivo is essential to understanding their biological roles. While a range of methods ...