Listar por tema "Melanoma"
Mostrando ítems 1-11 de 11
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Band selection in spectral imaging for non-invasive melanoma diagnosis
Optical Society of America (2013-03-04)A method consisting of the combination of the Synthetic Minority Over-Sampling TEchnique (SMOTE) and the Sequential Forward Floating Selection (SFFS) technique is used to do band selection in a highly imbalanced, small ... -
Determinación de la carga mutacional somática en piel sana y su relación con la pigmentación y la exposición solar en pacientes de la provincia de Castellón.
Universitat Jaume I (2019-05-15)Introduction. Melanoma is the skin cancer with the highest morbidity and mortality. Its main etiological factor is the incidence of solar ultraviolet (UV) radiation on the skin. This radiation can mutate epidermal cells’ ... -
Diagnóstico de sospecha de melanoma en atención primaria y prioridad de derivación a dermatología.
Universitat Jaume I (2019-05-16)Background: In our health system, most patients are referred to the Dermatology Unit by their Primary Care (PC) physician, who establishes the referral priority. The purpose of the present study was to evaluate the ... -
Diseño de un Programa de Intervención Diseño de un Programa de Intervención para la Prevención de Enfermedades por Exposición Solar en la Infancia.
Universitat Jaume I (2019-05-31)Introduction: Uncontrolled exposure to the sun is one of the risk factors for the appearance of diseases such as melanoma. The child population is the group most at risk. This risk can be significantly reduced if infants ... -
Epidemiologia de tumores malignos de la piel en el Departamento de Salud de la Plana
Universitat Jaume I (2019-06-04)BACKGROUND: Skin cancer is becoming one of the diseases with the greatest growth in our country, with a notable increase in the incidence rate, despite the fact that it is a pathology with low levels of incidence and ... -
Genetic variants in PARP1 (rs3219090) and IRF4 (rs12203592) genes associated with melanoma susceptibility in a Spanish population
BioMed Central (2013-03)Background Few high penetrance genes are known in Malignant Melanoma (MM), however, the involvement of low-penetrance genes such as MC1R, OCA2, ASIP, SLC45A2 and TYR has been observed. Lately, genome-wide association ... -
Incidencia del melanoma y características tumorales en el momento del diagnóstico en el Departamento de Salud de Castellón.
Universitat Jaume I (2019-04-16)Introduction. Melanoma incidence has continued rising during the last decades and its characteristics at the time of diagnosis are a fundamental factor in its prognosis and survival. The goal of this study was to describe ... -
El papel de la exposición solar, el genotipo del gen MC1R, el fototipo y la edad en la acumulación de mutaciones somáticas en piel humana normal.
Universitat Jaume I (2018-05-16)INTRODUCTION: P redisposition to skin cancer is influenced by genet ic and environmental factors. Ultraviolet radiation damages the DNA of epidermal cells. The progressive accumulation of somatic ... -
Papel de la radiación ultravioleta en la acumulación de mutaciones somáticas y caracterización de estas en piel normal.
Universitat Jaume I (2019-06-05)INTRODUCTION: Melanoma arises as a result of alterations in the genomes of skin cells, usually as a consequence of exposure to sun radiation. The detection of somatic mutations in normal cells promises to reveal fundamental ... -
Simultaneous purifying selection on the ancestral MC1R allele and positive selection on the melanoma-risk allele V60L in South Europeans
Oxford University Press (2013)In humans, the geographical apportionment of the coding diversity of the pigmentary locus melanocortin-1 receptor (MC1R) is, unusually, higher in Eurasians than in Africans. This atypical observation has been interpreted ... -
Singlet oxygen generation using a porous monolithic polymer supported photosensitizer: potential application to the photodynamic destruction of melanoma cells
Royal Society of Chemistry (2009-01)Photogeneration of singlet oxygen (1O2) by rose bengal is improved through the use of a porous monolithic polymer (PMP) as a support, as compared to a classic gel-type resin matrix. This type of monolithic polymeric ...