Listar por tema "Liquid chromatography"
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Advancing towards universal screening for organic pollutants in waters
Elsevier (2015)Environmental analytical chemists face the challenge of investigating thousands of potential organic pollutants that may be present in the aquatic environment. High resolution mass spectrometry (HRMS) hyphenated to ... -
Analytical strategy to investigate 3,4-methylenedioxypyrovalerone (MDPV) metabolites in consumers’ urine by high-resolution mass spectrometry
Springer (2016-01)The potential of high-resolution mass spectrometry (HRMS) for the investigation of human in vivo metabolism of 3,4-methylenedioxypyrovalerone (MDPV) using urine collected from a consumer (this is, in non-controlled ... -
Analytical study on ethephon residue determination in water by ion-pairing liquid chromatography/tandem mass spectrometry
Taylor & Francis (2011-11-22)A detailed analytical study on ethephon residue determination in water, making use of ion-pairing liquid chromatography coupled to electrospray tandem mass spectrometry (LC/MS/MS), has been carried out. Ethephon is a plant ... -
Application of advanced mass spectrometric techniques for the identification, metabolic characterisation and toxicological analysis of new psychoactive substances
Universitat Jaume I (2020-11-27)This Doctoral Thesis presents an in-depth investigation on NPS from the analytical chemistry point of view, being structured in three blocks. The first is focused on the analytical characterisation of different compounds, ... -
Are analysts doing method validation in liquid chromatography?
(2015-06-22)Method validation is being applied in the reported analytical methods for decades. Even before this protocol was defined, authors already somehow validated their methods without full awareness. They wished to assure the ... -
Critical evaluation of a simple retention time predictor based on LogKow as a complementary tool in the identification of emerging contaminants in water
Elsevier (2015)There has been great interest in environmental analytical chemistry in developing screening methods based on liquid chromatography–high resolution mass spectrometry (LC–HRMS) for emerging contaminants. Using HRMS, compound ... -
Detection and characterization of anabolic steroids in doping analysis by LC-MS
Elsevier (2008)The detection of target anabolic steroids in doping analysis has generally been performed by gas chromatography combined with mass spectrometry (GC-MS). However, liquid chromatography combined with tandem mass spectrometry ... -
Determination of eight nitrosamines in water at the ng L−1 levels by liquid chromatography coupled to atmospheric pressure chemical ionization tandem mass spectrometry
Elsevier (2011-09-19)In this work, we have developed a sensitive method for detection and quantification of eight N-nitrosamines, N-nitrosodimethylamine (NDMA), N-nitrosomorpholine (NMor), N-nitrosomethylethylamine (NMEA), N-nitrosopirrolidine ... -
Determination of sub-ppb epichlorohydrin levels in water by on-line solid-phase extraction liquid chromatography/tandem mass spectrometry
John Wiley (2009-06)A new sensitive and selective method based on on-line solid-phase extraction (SPE) coupled to liquid chromatography/electrospray ionization tandem mass spectrometry (LC/ESI-MS/MS) using a triple quadrupole mass spectrometer ... -
Development of a methodology to quantify tamoxifen and endoxifen in breast cancer patients by micellar liquid chromatography and validation according to the ICH guidelines
Elsevier (2011-04-15)A simple micellar liquid chromatographic procedure is described to determine tamoxifen and endoxifen in plasma. For the analysis, tamoxifen and endoxifen solutions were diluted in water and UV-irradiated for 20 min to form ... -
Fast determination of 40 drugs in water using large volume direct injection liquid chromatography–tandem mass spectrometry
Elsevier (2015)This work describes a rapid analytical method based on direct sample injection of water samples for the simultaneous identification/quantification of 40 emerging compounds, including pharmaceuticals and drugs of abuse. The ... -
Fragmentation pathways of drugs of abuse and their metabolites based on QTOF MS/MS and MSE accurate-mass spectra
John Wiley (2011-09)A study of the fragmentation pathways of several classes of drugs of abuse (cannabinoids, ketamine, amphetamine and amphetamine-type stimulants (ATS), cocaine and opiates) and their related substances has been made. The ... -
Half-width plots, a simple tool to predict peak shape, reveal column kinetics and characterise chromatographic columns in liquid chromatography: State of the art and new results
Elsevier (2013-11)Peak profiles in chromatography are characterised by their height, position, width and asymmetry; the two latter depend on the values of the left and right peak half-widths. Simple correlations have been found between the ... -
Identification of mycotoxins by UHPLC–QTOF MS in airborne fungi and fungi isolated from industrial paper and antique documents from the Archive of Bogotá
Elsevier (2016-01)Mold deterioration of historical documents in archives and libraries is a frequent and complex phenomenon that may have important economic and cultural consequences. In addition, exposure to toxic fungal metabolites might ... -
Investigation of pesticide metabolites in food and water by LC-TOF-MS
Elsevier (2008)We illustrate the potential of liquid chromatography with (quadrupole) time-of-flight mass spectrometry [LC-(Q)TOF-MS] in investigating the presence of pesticide metabolites in food and water samples. The higher polarity ... -
Investigation of pharmaceuticals in processed animal by-products by liquid chromatography coupled to high-resolution mass spectrometry
Elsevier (2016-07)There is an on-going trend for developing more sustainable salmon feed in which traditionally applied marine feed ingredients are replaced with alternatives. Processed animal products (PAPs) have been re-authorized as novel ... -
Method development and validation for the determination of selected endocrine disrupting compounds by liquid chromatography mass spectrometry and isotope pattern deconvolution in water samples. Comparison of two extraction techniques
Royal Society of Chemistry (2016)In the present work two different extraction methodologies have been developed and validated for the determination of t-octylphenol and a technical mixture of nonylphenol (both, priority substances of EU water policy) and ... -
Micellar Liquid Chromatography Recent Advances and Applications
Hindawi Publishing Corporation (2012-01)A practical liquid chromatographic method has been developed for the selective determination of the levels of spermine in anchovy sauce after derivatization with 3,5 dinitrobenzoyl chloride. The micellar liquid chromatographic ... -
Monitoring strychnine and brucine in biochemical samples using direct injection micellar liquid chromatography
Royal Society of Chemistry (2013)Nux-vomica is a tropical plant that contains two ergot alkaloids i.e. strychnine and brucine which have pharmaceutical and toxic properties. In some places, for example in India, Nux-vomica is used in ayurvedic preparations ... -
No transfer of the non-regulated mycotoxins, beauvericin and enniatins, from feeds to farmed fish reared on plant-based diets
Elsevier (2020-09-01)Concern about the risk of exposure to emerging plant-derived mycotoxins such as beauvericin and enniatins has been addressed by the European Commission who requested the European Food Safety Authority for a scientific ...