Listar por tema "Ion channels"
Mostrando ítems 1-4 de 4
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Directional ion selectivity in a biological nanopore with bipolar structure
Elsevier (2009)Ion transport features of a biological nanopore, the bacterial porin OmpF from Escherichia coli, have been investigated by patch-clamp experiments performed at the single channel level. Membrane potential measurements done ... -
Divalent cations reduce the pH sensitivity of OmpF channel inducing the pKa shift of key acidic residues
RSC Publishing (2010-11-03)In contrast to the highly-selective channels of neurophysiology employing mostly the exclusion mechanism, different factors account for the selectivity of large channels. Elucidation of these factors is essential for ... -
Electrical pumping of potassium ions against an external concentration gradient in a biological ion channel
AIP Publishing (2013-07-22)We show experimentally and theoretically that significant currents can be obtained with a biological ion channel, the OmpF porin of Escherichia coli, using zero-average potentials as driving forces. The channel rectifying ... -
Ion channel activity of the CSFV p7 viroporin in surrogates of the ER lipid bilayer
Elsevier (2016-01)Viroporins comprise a family of non-structural proteins that play significant and diverse roles during the replication cycle of many animal viruses. Consequently, they have become promising targets for inhibitory drug and ...