Listar por tema "Ethanol"
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Acquisition and reconditioning of ethanol-induced conditioned place preference in mice is blocked by the H2O2 scavenger alpha lipoic acid
Springer (2012)Rationale Hydrogen peroxide (H2 O2) is the co-substrate used by catalase to metabolize ethanol to acetaldehyde in the brain. This centrally formed acetaldehyde has been involved in several ethanol-related behaviors. ... -
Age- and sex-related differences in the acquisition and reinstatement of ethanol CPP in mice
Elsevier (2012)Many people begin to experiment with alcohol during adolescence, an important developmental period during which sex differences in the effects of ethanol appear. In the present study we evaluated the effect of ethanol (0, ... -
Alcohol y lactància: una revisión sistemática
Universitat Jaume I (2019-04-15)Introduction: Ethanol is the most consumed drug worldwide with severe repercussions and serious economic and social impact. Its consequences are a major burden in our healthcare system, acting as a risk factor for multiple ... -
Alpha-lipoic acid, a scavenging agent for H2O2, reduces ethanol-stimulated locomotion in mice
Springer-Verlag (2011-07-19)Rationale The main system of central ethanol oxidation is mediated by the enzyme catalase. By reacting with H2O2, brain catalase forms compound I (the catalase–H2O2 system), which is able to oxidize ethanol to acetaldehyde ... -
Anxiogenic and stress-inducingeffects of peripherally administeredacetaldehyde in mice: Similarities with the disulfiram–ethanol reaction
Elsevier (2012)Peripheral accumulation of acetaldehyde, the first metabolite of ethanol, produces autonomic responses in humans called “flushing”. The aversive characteristics of flushing observed in some populations with an isoform of ... -
Atención de enfermería en el trastorno por uso de alcohol : Una revisión integradora
Universitat Jaume I (2019-05-31)Introduction: Nursing in Mental Health encompasses the individual and group care of the patient suffering from mental health disorders. The evolution of mental health nursing has been conditioned both by the evolution ... -
Behavioral sensitization, opioid system and context
Universitat Jaume I (2016-07-20)A major difficulty in treating alcohol addiction is the high rate of relapse even after prolonged abstinence. Relapse can be triggered by many factors, including stress, re-exposure to the drug, conditioned stimuli and ... -
Caffeine modulates voluntary alcohol intake in mice depending on theaccess conditions: Involvement of adenosine receptors and the role of individual differences
Elsevier (2019)Caffeine is the most consumed psychoactive stimulant and the main active ingredient of energy drinks.Epidemiology studies have shown a positive correlation between the consumption of energy drinks and that ofethanol. The ... -
Consecuencias de la acción del calcio intracelular en la activación de la proteína Kinasa A y las consecuencias a nivel conductual de su manipulación
Universitat Jaume I (2016-07-20)El estresante estilo de vida de la sociedad actual junto con la mala concepción sobre las posibles consecuencias del consumo de alcohol podrían ser algunas de las causas de que actualmente ... -
Dantrolene blockade of ryanodine receptor impairs ethanol-induced behavioral stimulation, ethanol intake and loss of righting reflex
Elsevier (2012-08)Calcium has been characterized as one of the most ubiquitous, universal and versatile intracellular signals. Among other substances with the ability to alter intracellular calcium levels, ethanol has been described as ... -
Efecto del consumo de alcohol sobre la célula B pancreática durante el síndrome metabólico.
Universitat Jaume I (2018-06-07)Introduction : The metabolic syndrome (MS) is a clinical condition that presents several risk factors that make it the prelude to Diabetes Mellitus type 2 (DM2). Et h anol abuse induce s alterations ... -
Ethanol drinking-in-the-dark facilitates behavioral sensitization to ethanol in C57BL/6J, BALB/cByJ, but not in mu-opioid receptor deficient CXBK mice
Elsevier (2012)Background: Neuroplasticity associated with drug-induced behavioral sensitization has been associated with excessive drug pursuit and consumption characteristic of addiction. Repeated intraperitoneal (ip) injections of ... -
Impact of TLR4 on behavioral and cognitive dysfunctions associated with alcohol-induced neuroinflammatory damage
Elsevier (2011-06-01)Toll-like receptors (TLRs) play an important role in the innate immune response, and emerging evidence indicates their role in brain injury and neurodegeneration. Our recent results have demonstrated that ethanol is capable ... -
La Inducción del citocromo P450 2E1 en el cerebro aumenta la actividad locomotora producida por el etanol en ratones
Universitat Jaume I (2014-06-16)In the central nervous system ethanol (EtOH) is metabolized into acetaldehyde by different enzymes. Brain catalase accounts for 60% of the total production of ETOH-derived acetaldehyde, whereas cerebral cytochrome P450 ... -
Intracellular calcium chelation with BAPTA-AM modulates ethanol-induced behavioral effects in mice
Elsevier (2012)Calcium (Ca2+) has been characterized as one of the most ubiquitous, universal and versatile intracellular signaling molecules responsible for controlling numerous cellular processes. Ethanol-induced effects on Ca2+ ... -
Involvement of the beta-endorphin neurons of the hypothalamic arcuate nucleus in ethanol-induced place preference conditioning in mice
Wiley (2011-10-20)Background: Increasing evidence indicates that mu- and delta-opioid receptors are decisively involved in the retrieval of memories underlying conditioned effects of ethanol. The precise mechanism by which these receptors ... -
Modulation of ethanol-induced conditioned place preference in mice by 3-amino-1,2,4-triazole and D-penicillamine depends on ethanol dose and number of conditioning trials
Springer (2013)Previous studies have shown that both 3-amino-1,2,4-triazole (AT), which inhibits metabolism of ethanol (EtOH) to acetaldehyde by inhibiting catalase, and D-penicillamine (D-P), an acetaldehyde-sequestering agent, modulate ... -
Papel del calcio celular en las conductas inducidas por el etanol
Universitat Jaume I (2018-06-06)Introduction: Ethanol is the most consumed drug world wide . It produces behavioral changes in a chronic manner and when acute administered. It has been show n that some of these changes are modulated ... -
Participation of L-type calcium channels in ethanol-induced behavioral stimulation and motor incoordination: Effects of diltiazem and verapamil
Elsevier (2010-06)Calcium flux through voltage gate calcium channels (VGCC) is involved in many neuronal processes such as membrane depolarization, gene expression, hormone secretion, and neurotransmitter release. Several studies have shown ... -
Piecing together the puzzle of acetaldehyde as a neuroactive agent
Elsevier (2012-01)Mainly known for its more famous parent compound, ethanol, acetaldehyde was first studied in the 1940s, but then research interest in this compound waned. However, in the last two decades, research on acetaldehyde has seen ...