• openAccess   A Meta-analytic Review: Psychological Treatment of Subthreshold Depression in Children and Adolescents 

      Cuijpers, Pim; Pineda, Blanca; Ng, Mei Yi; Weisz, John; Muñoz, Ricardo F.; Gentili, Claudio; Quero, Soledad; Karyotaki, Eirini Elsevier (2021-02-14)
      Objective: Subthreshold depression has been found to be associated with considerable impairment and an increased risk of developing major depression. Although several randomized trials have examined the effects of ...
    • closedAccess   Care-as-usual control groups across different settings in randomized trials on psychotherapy for adult depression: a meta-analysis 

      Cuijpers, Pim; Quero, Soledad; Papola, Davide; Cristea, Ioana Alina; Karyotaki, Eirini Cambridge University Press (2019)
      Background. Care-as-usual (CAU) is often used as a control condition in psychotherapy research, but it may vary considerably what that entails, ranging from no treatment, to routine treatment in primary care, general ...
    • openAccess   Efficacy of Self-guided Internet-Based Cognitive Behavioral Therapy in the Treatment of Depressive Symptoms: A Meta-analysis of Individual Participant Data 

      Karyotaki, Eirini; Riper, Heleen; twisk, jos; Hoogendoorn, Adriaan; Kleiboer, A.; Mira, Adriana; Mackinnon, Andrew; Meyer, B.; Botella, Cristina; Littlewood, Elizabeth; Andersson, Gerhard; Christensen, Helen; Klein, Jan P.; Schröder, Johanna; Bretón-López, Juana; Scheider, Justine; Griffiths, K.; Farrer, Louise; Huibers, M. J. H.; Phillips, Rachel; Gilbody, Simon; Moritz, Steffen; Berger, Thomas; pop, victor; Spek, Viola; Cuijpers, Pim American Medical Association (2017-02)
      - Importance: Self-guided internet-based cognitive behavioral therapy (iCBT) has the potential to increase access and availability of evidence-based therapy and reduce the cost of depression treatment. - Objectives: ...
    • openAccess   Is self-guided internet-based cognitive behavioural therapy (iCBT) harmful? An individual participant data meta-analysis 

      Karyotaki, Eirini; Kemmeren, Lise; Riper, Heleen; Twisk, Jos; Hoogendoorn, Adriaan; Kleiboer, Annet; Mira, Adriana; Mackinnon, Andrew; Meyer, Björn; Botella, Cristina; Littlewood, Elizabeth; Andersson, Gerhard; Christensen, Helen; Klein, Jan P.; Schröder, Johanna; Bretón-López, Juana; Scheider, Justine; Griffiths, Kathy; Farrer, Louise; Huibers, Marcus J. H.; Phillips, Rachel; Gilbody, Simon; Moritz, Steffen; Berger, Thomas; Pop, Victor; Spek, Viola; Cuijpers, Pim Cambridge University Press (2018)
      Background. Little is known about potential harmful effects as a consequence of self-guided internet-based cognitive behaviour therapy (iCBT), such as symptom deterioration rates. Thus, safety concerns remain and hamper ...
    • openAccess   Online prevention programmes for university students: stakeholder perspectives from six European countries 

      Irish, Madeleine; Kuso, Stefanie; Simek, Monika; Zeiler, Michael; Potterton, Rachel; Musiat, Peter; Nitsch, Martina; Wagner, Gudrun; karwautz, andreas; Bolinski, Felix; Karyotaki, Eirini; Soler Rovira, Carla; Etchemendy, Ernestina; HERRERO ROMERO, ROCIO; Mira, Adriana; Cormo, Giulia; Baños, Rosa Maria; García-Palacios, Azucena; Ebert, David Daniel; Franke, Marvin; Zarski, Anna-Carlotta; Weisel, Kiona K.; Berger, Thomas; Dey, Michelle; Schaub, Michael P.; Jacobi, Corinna; Botella, Cristina; Oliver, Elia; Gordon, Gemma; Spencer, Lucy; Waldherr, Karin; Waldherr; Schmidt, Ulrike Oxford University Press (2021-07-07)
      Background: Students beginning university are at a heightened risk for developing mental health disorders. Online prevention and early intervention programmes targeting mental health have the potential to reduce this ...
    • openAccess   Predictors of treatment dropout in self-guided web-based interventions for depression: an ‘individual patient data’ meta-analysis 

      Karyotaki, Eirini; Kleiboer, A.; Smit, F.; Turner, D. T.; Mira, Adriana; Andersson, Gerhard; Berger, Thomas; Botella, Cristina; Bretón-López, Juana; Carlbring, Per; Christensen, Helen; De Graaf, E.; Griffiths, K.; Donker, T.; Farrer, Louise; Huibers, M. J. H.; Lenndin, J.; Mackinnon, Andrew; Meyer, B.; Moritz, S.; Riper, H.; Spek, V.; Vernmark, K.; Cuijpers, Pim Cambridge University Press (2015)
      Background. It is well known that web-based interventions can be effective treatments for depression. However, dropout rates in web-based interventions are typically high, especially in self-guided web-based interventions. ...
    • openAccess   Psychologic Treatment of Depression Compared With Pharmacotherapy and Combined Treatment in Primary Care: A Network Meta-Analysis 

      Cuijpers, Pim; Oud, Matthijs; Karyotaki, Eirini; Noma, Hisashi; Quero, Soledad; Cipriani, Andrea; arroll, bruce; Furukawa, Toshi Annals of Family Medicine (2021-05)
      PURPOSE Most patients with depression are treated by general practitioners, and most of those patients prefer psychotherapy over pharmacotherapy. No network meta-analyses have examined the effects of psychotherapy compared ...
    • openAccess   Psychological interventions to prevent the onset of depressive disorders: A meta-analysis of randomized controlled trials 

      Cuijpers, Pim; Pineda, Blanca; Quero, Soledad; Karyotaki, Eirini; Struijs, Sascha; Figueroa, Caroline; Llamas, Jazmin A.; Furukawa, Toshi; Muñoz, Ricardo F. Elsevier (2021-02-01)
      Purpose: Depressive disorders are common and have a considerable impact on patients and societies. Several treatments are available, but their effects are modest and reduce the burden only to a limited extent. Preventing the ...
    • openAccess   Psychological treatment of depression with other comorbid mental disorders: systematic review and meta-analysis 

      Cuijpers, Pim; Miguel, Clara; Ciharova, Marketa; Quero, Soledad; Plessen, Constantin Yves; Ebert, David Daniel; Harrer, Mathias; van Straten, Annemieke; Karyotaki, Eirini Taylor & Francis (2023-01-31)
      Most people with a mental disorder meet criteria for multiple disorders. We conducted a systematic review and meta-analysis of randomized trials comparing psychotherapies for people with depression and comorbid other mental ...
    • openAccess   Psychological treatment of perinatal depression: a meta-analysis 

      Cuijpers, Pim; Franco, Pamela; Ciharova, Marketa; Miguel, Clara; Segre, Lisa; Quero, Soledad; Karyotaki, Eirini Cambridge University Press (2023)
      Background: Depression during pregnancy and after the birth of a child is highly prevalent and an important public health problem. Psychological interventions are the first-line treatment and, although a considerable ...
    • openAccess   Psychotherapies for depression: a network meta-analysis covering efficacy, acceptability and long-term outcomes of all main treatment type 

      Cuijpers, Pim; Quero, Soledad; Noma, Hisashi; Ciharova, Marketa; Miguel Sanz, Clara; Karyotaki, Eirini; Cipriani, Andrea; Cristea, Ioana Alina; Furukawa, Toshi John Wiley & Sons (2021-06)
      The efects of psychotherapies for depression have been examined in several hundreds of randomized trials, but no recent network meta-analysis (NMA) has integrated the results of these studies. We conducted an NMA of trials ...
    • openAccess   The Contribution of “Individual Participant Data” Meta-Analyses of Psychotherapies for Depression to the Development of Personalized Treatments: A Systematic Review 

      Cuijpers, Pim; Ciharova, Marketa; Quero, Soledad; Miguel, Clara; Driessen, Ellen; Harrer, Mathias; purgato, marianna; Ebert, David Daniel; Karyotaki, Eirini MDPI (2022-01-11)
      While randomized trials typically lack sufficient statistical power to identify predictors and moderators of outcome, ”individual participant data” (IPD) meta-analyses, which combine primary data of multiple randomized ...