Listar por autoría "fda577af-1f88-46b6-b833-411ad80a3a66"
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A possible use of melatonin in the dental field: Protein adsorption andinvitrocell response on coated titanium
Elsevier (2020)Melatonin (MLT) is widely known for regulating the circadian cycles and has been studied for its role in boneregeneration and inflammation. Its application as a coating for dental implants can condition the local ... -
Bioactive zinc-doped sol-gel coating modulates protein adsorption patterns and in vitro cell responses
Elsevier (2020-12-30)Zinc is an essential element with an important role in stimulating the osteogenesis and mineralization and suppressing osteoclast differentiation. In this study, new bioactive ZnCl2-doped sol-gel materials were designed ...
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Characterization of magnesium doped sol-gel biomaterial for bone tissue regeneration: The effect of Mg ion in protein adsorption
Elsevier (2021-06-01)Magnesium is the fourth most abundant element in the human body with a wide battery of functions in the maintenance of normal cell homeostasis. In the bone, this element incorporates in the hydroxyapatite structure and it ...
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Complex effects of Mg-biomaterials on the osteoblast cell machinery: A proteomic study
Elsevier (2022)The cell–biomaterial interface is highly complex; thousands of molecules and many processes participate in its formation. Growing demand for improved biomaterials has highlighted the need to understand the structure and ...
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Correlation between biological responses in vitro and in vivo to Ca-doped sol-gel coatings assessed using proteomic analysis
Elsevier (2022-10-21)Poor correlation between the results of in vitro testing and the subsequent in vivo experiments hinders the design of biomaterials. Thus, new characterisation methods are needed. This study used proteomic and histological ...
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Development and characterisation of strontium-doped sol-gel coatings to optimise the initial bone regeneration processes
Elsevier (2022)Strontium plays an important role in bone regeneration; it promotes the differentiation and maturation of osteoblasts and inhibits the activity of osteoclasts. Our principal objective in this study was to formulate new ...
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Effect of Trichoderma viride pre‐inoculation in pine species with different levels of susceptibility to Fusarium circinatum: physiological and hormonal responses
(2019)Pine pitch canker (PPC), caused by Fusarium circinatum, affects Pinus species worldwide. Although no effective solutions have yet been found to control it, there is a growing interest in using biological control agents ... -
Enhancing the correlation between in vitro and in vivo experiments in dental implant osseointegration: investigating the role of Ca ions
Royal Society of Chemistry (2024-02-16)This study delves into the osteogenic potential of a calcium-ion modified titanium implant surface, unicCa, employing state-of-the-art proteomics techniques both in vitro (utilizing osteoblasts and macrophage cell cultures) ...
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Evaluation of the inflammatory responses to sol–gel coatingswith distinct biocompatibility levels
John Wiley and Sons (2021-02-20)The immune system plays a crucial role in determining the implantation outcome, and macrophages are in the frontline of the inflammatory processes. Further, cellular oxidative stress resulting from the material recognition ...
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Influence of calcium ion-modified implant surfaces in protein adsorption and implant integration
Springer (2021-04-21)Calcium (Ca) is a well-known element in bone metabolism and blood coagulation. Here, we investigate the link between the protein adsorption pattern and the in vivo responses of surfaces modified with calcium ions (Ca-ion) ...
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Insight into the antibacterial mechanism of Cu-enriched sol–gel coatings employing proteomics
Royal Society of Chemistry (2023)Advanced antibacterial biomaterials can help reduce the severe consequences of infections. Using copper compounds is an excellent option to achieve this goal; they offer a combination of regenerative and antimicrobial ...
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Phosphite shifts physiological and hormonal profile of Monterey pine and delays Fusarium circinatum progression
Elsevier (2017)Fusarium circinatum is the causal agent of pitch canker disease affecting Pinus spp. and Pseudotsuga menziesii worldwide. Under strict quarantine measures, alternative approaches for disease control are necessary. Phosphite ...
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Protein adsorption/desorption dynamics on Ca‑enriched titanium surfaces: biological implications
Springer (2021-08-27)Calcium ions are used in the development of biomaterials for the promotion of coagulation, bone regeneration, and implant osseointegration. Upon implantation, the time-dependent release of calcium ions from titanium implant ...
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Proteomic analysis of calcium-enriched sol–gel biomaterials
Springer (2019-04)Calcium is an element widely used in the development of biomaterials for bone tissue engineering as it plays important roles in bone metabolism and blood coagulation. The Ca ions can condition the microenvironment at the ...
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Proteomic Analysis of Mesenchymal Stem Cells and Monocyte Co-Cultures Exposed to a Bioactive Silica-Based Sol–Gel Coating
American Chemical Society (2023)New methodologies capable of extensively analyzing the cell-material interactions are necessary to improve current in vitro characterization methods, and proteomics is a viable alternative. Also, many studies are focused ...
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Proteomic evaluation of human osteoblast responses to titanium implants over time
Wiley (2022-08-30)Titanium is widely used in bone prostheses due to its excellent biocompatibility and osseointegration capacity. To understand the effect of sandblasted acid-etched (SAE) Ti implants on the biological responses of human ...
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Proteomics as a tool to study the osteoimmunomodulatory role of metallic ions in a sol–gel coating
Royal Society of Chemistry (2023)The success of bone implants depends on the osteoimmunomodulatory (OIM) activity of the biomaterials in the interactions with the periimplantary tissues. Many in vitro tests have been conducted to evaluate the osteoimmunology ...
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Sol-gel coatings for metallic prosthesis from methyl-modified alkoxysilanes: balance between protection and bioactivation
Elsevier (2020)The reported osteogenic properties of the hybrid silica sol-gel materials make these compositions perfect candidates for bone tissue engineering applications. The aim of this study was the synthesis and characterisation ...
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The effect of calcium–magnesium mixtures in sol–gel coatings on bone tissue regeneration
Royal Society of Chemistry (2022)Calcium and magnesium are two elements essential for bone structure and metabolism. However, their synergistic or competitive effects on bone regeneration are often overlooked during biomaterial development. We examined ...
