Listar por autoría "f85a540a-cc2c-46d3-81bb-959cc1411439"
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Behavioral manipulations for the improvement of anergia: impact on the mesolimbic dopaminergic system
Olivares-García, Régulo Universitat Jaume I (2016-07-20)Studies with animals have shown that exercise can have neuroprotective effects which has led to suggestions that physical exercise could have positive effects in the prevention/treatment of various neurologic or psychiatric ... -
Caffeine Modulates Food Intake Depending on the Context That Gives Access to Food: Comparison With Dopamine Depletion
Correa, Merce; San Miguel Segura, Noemí; López Cruz, Laura; Carratalá-Ros, Carla; Olivares-García, Régulo; Salamone, John (2018-09-06)Caffeine is a methylxanthine consumed in different context s to potentiate alertness and reduce fatigue. However, caffeine can induce anxiety at hig h doses. Caffeine is also a minor psychostimulant that seems to act ... -
Efecto de la modulación dopaminérgica en la preferencia por reforzadores activos en ratones con una mutación en el factor de transcripción Pitx3
Verdejo-Penyarrocha, Mireia; Martínez-Verdú, Andrea; Olivares-García, Régulo; Matas-Navarro, Paula; Carratalá-Ros, Carla Publicacions de la Universitat Jaume I. Servei de Comunicació i Publicacions (2022)La conducta motivada está caracterizada por altos niveles de activación, vigor y persistencia. La dopamina del núcleo accumbens (nacb) está implicada en regular este componente energizante de la motivación, incluida la ... -
Effects of the dopamine depleting agent tetrabenazine in tests evaluating different components of depressive-like behavior in mice : sex-dependent response to antidepressant drugs with SERT and DAT blocker profiles
Carratalá Ros, Carla; Martínez‑Verdú, Andrea; Olivares-García, Régulo; Salamone, John; Correa, Merce Springer Nature (2023-07-05)Background ; Depression is a disorder twice as common in women than in men. There are sex differences in the symptomatology and treatment response to this disorder. Impairments in behavioral activation (i.e. anergia, ... -
Energizing effects of bupropion on effortful behaviors in mice under positive and negative test conditions: modulation of DARPP-32 phosphorylation patterns
Carratalá-Ros, Carla; Olivares-García, Régulo; Martínez-Verdú, Andrea; Arias-Sandoval, Edgar; Salamone, John; Correa, Merce Springer (2021-09-09)Motivational symptoms such as anergia, fatigue, and reduced exertion of effort are seen in depressed people. To model this, nucleus accumbens (Nacb) dopamine (DA) depletions are used to induce a low-effort bias in rodents ... -
Impact of Fluoxetine on Behavioral Invigoration of Appetitive and Aversively Motivated Responses: Interaction With Dopamine Depletion
Carratalá-Ros, Carla; López Cruz, Laura; Martínez Verdú, Andrea; Olivares-García, Régulo; Salamone, John; Correa, Merce Frontiers Media (2021)Impaired behavioral activation and effort-related motivational dysfunctions like fatigue and anergia are debilitating treatment-resistant symptoms of depression. Depressed people show a bias towards the selection of low ... -
Individual differences in running wheel performance and preference for active versus passive reinforcers: role of DARPP32
Olivares-García, Régulo Universitat Jaume I (2017-09-21)Background: Motivation is characterized by high levels of behavioral activation, vigor, persistence and goal directed behavior. These functions are impair ed in pathologies such as depression or Parkinson disease. ... -
La reducción de los niveles de dopamina no altera la conducta de «atracón de comida» en ratones, pero la cafeína modula el consumo en función de los niveles de ansiedad.
Olivares-García, Régulo; San Miguel Segura, Noemí; Pérez García, José Manuel; Camañes Martorell, Joan; Correa, Merce Universitat Jaume I (2016)Introducción: La conducta de «atracón» consiste en consumir, en un período breve de tiempo, más cantidad de alimentos del que se consumiría normalmente en situaciones similares y en un plazo de tiempo igual. Es una ... -
Sex and age differences in mice models of effort-based decision-making and anergia in depression : the role of dopamine, and cerebral-dopamine-neurotrophic-factor
Matas-Navarro, Paula; Carratalá Ros, Carla; Olivares-García, Régulo; Martínez-Verdú, Andrea; Salamone, John; Correa, Merce Springer Nature (2023-08-18)Mesolimbic dopamine (DA) regulates vigor in motivated behavior. While previous results have mainly been performed in male rodents, the present studies compared CD1 male and female mice in effort-based decision-making tests ...