Listar por autoría "d936669d-b8f3-444d-b8a1-0fbf1cd51f2e"
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A model-driven transformation approach for the modelling of processes in clinical practice guidelines
Martínez-Salvador, Begoña; Marcos, Mar; Palau, Patricia; Domínguez Mafé, Eloy Elsevier (2023)Clinical Practice Guidelines (CPGs) include recommendations aimed at optimising patient care, informed by a review of the available clinical evidence. To achieve their potential benefits, CPG should be readily available at ... -
Beta‐blockers withdrawal in patients with heart failure with preserved ejection fraction and chronotropic incompetence: Effect on functional capacity rationale and study design of a prospective, randomized, controlled trial (The Preserve‐HR trial)
Palau, Patricia; Seller, Julia; Domínguez Mafé, Eloy; Gómez, Inés; Ramón, José María; Sastre, Clara; De la Espriella, Rafael; Santas, Enrique; Miñana, Gema; Chorro, Francisco J.; González Juanatey, José Ramón; Nuñez, Julio Wiley (2020)Background: The pathophysiology of heart failure with preserved ejection fraction (HFpEF) is complex and multifactorial. Chronotropic incompetence (ChI) has emerged as a crucial pathophysiological mechanism. Beta‐blockers, ... -
Carga de hospitalizaciones recurrentes tras una hospitalización por insuficiencia cardiaca aguda: insuficiencia cardiaca con función sistólica conservada frente a reducida
Santas, Enrique; Valero, Ernesto; Mollar, Anna; García-Blas, Sergio; Palau, Patricia; Miñana, Gema; Núñez, Eduardo; Sanchis, Juan; Chorro, Francisco J.; Núñez, Julio Elsevier (2016-11)Introduction and objectives: Heart failure with preserved ejection fraction and reduced ejection fraction share a high mortality risk. However, differences in the rehospitalization burden over ti ... -
Changes in myocardial iron content following administration of intravenous iron (Myocardial‐IRON): Study design
Miñana, Gema; Cardells, Ingrid; Palau, Patricia; Llàcer, Pau; Facila Rubio, Lorenzo; Almenar, Luis; López‐Lereu, Maria Pilar; Monmeneu, Jose V.; Amiguet, Martina; González, Jessika; Serrano, Alicia; Montagud, Vicente; López‐Vilella, Raquel; Valero, Ernesto; García-Blas, Sergio; Bodí, Vicent; de la Espriella-Juan, Rafael; Sanchis, Juan; Chorro, Francisco J.; Bayes-Genis, Antoni; Núñez, Julio; Myocardial‐IRON Investigators Wiley (2018)Treatment with intravenous ferric carboxymaltose (FCM) has been shown to improve symptoms, functional capacity, and quality of life in patients with heart failure and iron deficiency. However, the underlying mechanisms for ... -
Chronotropic index and long-term outcomes in heart failure with preserved ejection fraction
Palau, Patricia; Domínguez Mafé, Eloy; Seller, Julia; Sastre, Clara; Sanchis, Juan; López, Laura; Bodí, Vicent; Llàcer, Pau; Miñana, Gema; De la Espriella, Rafael; Bayes-Genis, Antoni; Núñez, Julio Elsevier (2022)Introduction and objectives: Little is known about the usefulness of heart rate (HR) response to exercise for risk stratification in heart failure with preserved ejection fraction (HFpEF). Therefore, this study aimed ... -
Clinical utility of cardiopulmonary exercise testing in patients with heart failure with preserved ejection fraction
Palau, Patricia Wiley (2018-02)Dr Corrà and colleagues review the prognostic role of cardiopulmonary exercise testing (CPET) in heart failure (HF) and consider individual patient characteristics, the modality of CPET execution, and newer clinical ... -
Dapagliflozin and short-term changes on circulating antigen carbohydrate 125 in heart failure with reduced ejection fraction
Amiguet, Martina; Palau, Patricia; Domínguez Mafé, Eloy; Seller, Julia; GARCIA-PINILLA, JOSE MANUEL; De la Espriella, Rafael; Miñana, Gema; Valle, Alfonso; Sanchis, Juan; Górriz, José Luis; Bayes-Genis, Antoni; DAPA-VO2 Investigators, /; Núñez, Julio Nature Research (2023)Circulating antigen carbohydrate 125 (CA125) has emerged as a proxy of fluid overload in heart failure. This study aimed to evaluate the effect of dapagliflozin on short-term CA125 levels in patients with stable heart ... -
Differential prognostic impact of type 2 diabetes mellitus in women and men with heart failure with preserved ejection fraction
Palau, Patricia; Bertomeu-González, Vicente; Sanchis, Juan; Soler Costa, Meritxell; De la Espriella, Rafael; Domínguez Mafé, Eloy; Santas, Enrique; Núñez, Eduardo; Chorro, Francisco J.; Miñana, Gema; Bayes-Genis, Antoni; Núñez, Julio Elsevier (2019)Introduction and objectives Type 2 diabetes mellitus (DM2) is a common comorbidity in patients with heart failure (HF) with preserved ejection fraction (HFpEF). Previous studies have shown that diabetic women are at ... -
Early effects of empagliflozin on exercise tolerance in patients with heart failure: A pilot study.
Núñez, Julio; Palau, Patricia; Domínguez Mafé, Eloy; Mollar, Anna; Núñez, Eduardo; Ramón, José María; Miñana, Gema; Santas, Enrique; Facila Rubio, Lorenzo; Górriz, José Luis; Sanchis, Juan; Bayes-Genis, Antoni Wiley (2018-04-17)Background: Sodium-glucose linked transporter 2 inhibition recently emerged as a promising ther- apy for reducing the risk of heart failure (HF) in patients with type 2 diabetes mellitus (T2DM). However, there is a lack ... -
Effect of a home-based inspiratory muscular training programme on functional capacity in patients with chronic COVID-19 after a hospital discharge: protocol for a randomised control trial (InsCOVID trial)
Palau, Patricia; Domínguez Mafé, Eloy; Sastre, Clara; Martínez Mas, María Luz; Gonzalez, Cruz; Bondía, Elvira; Albiach, Cristina; Núñez, Julio; López, Laura BMJ Publishing Group (2022)Introduction: Exercise intolerance and fatigue are the most common symptoms in patients with chronic COVID-19 after hospital discharge. Supervised exercise training programmes improve symptoms, but scarce research has been ... -
Effect of β-Blocker Withdrawal on Functional Capacity in Heart Failure and Preserved Ejection Fraction
Palau, Patricia; Seller, Julia; Domínguez Mafé, Eloy; Sastre, Clara; Ramón, Jose María; De la Espriella, Rafael; Santas, Enrique; Miñana, Gema; Bodí, Vicent; Sanchis, Juan; Valle, Alfonso; Chorro, F. Javier; Llácer, Pau; Bayes-Genis, Antoni; Núñez, Julio Elsevier (2021-11-15)BACKGROUND Chronotropic incompetence has shown to be associated with a decrease in exercise capacity in heart failure with preserved ejection fraction (HFpEF), yet b-blockers are commonly used in HFpEF despite the lack ... -
Entrenamiento de la musculatura inspiratoria y la electroestimulación muscular funcional en el tratamiento de la insuficiencia cardiaca con función sistólica conservada: estudio TRAINING-HF
Palau, Patricia; Domínguez Mafé, Eloy; López, Laura; Ramón, José María; Heredia, Raquel; González, Jessika; Santas, Enrique; Bodí, Vicent; Miñana, Gema; Valero, Ernesto; Mollar, Anna; Bertomeu-González, Vicente; Chorro, Francisco J.; Sanchis, Juan; Lupón, Josep; Bayes-Genis, Antoni; Núñez, Julio Elsevier (2018)Introducción y objetivos No se dispone de tratamientos farmacológicos que demuestren reducir la morbimortalidad asociada en pacientes con insuficiencia cardiaca y función sistólica conservada (IC-FEc). El objetivo del ... -
Evaluation of a novel biomarker of type XXVIII collagen formation, PRO-C28, in samples from cancer and heart failure with preserved ejection fraction patients
Reese-Petersen, Alexander; Willumsen, Nicholas; Palau, Patricia; Nunez, Julio; Sun, Shu; manon-jensen, tina; Kamall, Bibi; Karsdal, Morten; Genovese, Federica Elsevier (2021-08-03)Increased turnover of extracellular matrix proteins is seen in many different diseases and is an underlying and driving feature of pathogenesis. An increased ratio of formation over degradation of extracellular matrix ... -
Heart rate response and functional capacity in patients with chronic heart failure with preserved ejection fraction
Domínguez Mafé, Eloy; Palau, Patricia; Núñez, Eduardo; Ramón, José María; López, Laura; Melero, Joana; Bellver, Alejandro; Santas, Enrique; Chorro, Francisco J.; Núñez, Julio Wiley (2018)Aims: The mechanisms of exercise intolerance in heart failure with preserved ejection fraction (HFpEF) are not yet elucidated. Chronotropic incompetence has emerged as a potential mechanism. We aimed to evaluate whether ... -
Home-based inspiratory muscle training for management of older patients with heart failure with preserved ejection fraction: does baseline inspiratory muscle pressure matter?
Palau, Patricia; Domínguez Mafé, Eloy; Ramón, José María; López, Laura; Briatore, Antonio Ernesto; Tormo, J. Pablo; Ventura, Bruno; Chorro, Francisco J.; Núñez, Julio SAGE (2019-05-31)Background: Heart failure with preserved ejection fraction is a clinical syndrome characterised by reduced exercise capacity. Some evidence has shown that a simple and home-based programme of inspiratory muscle training ... -
Inspiratory Muscle Function and Exercise Capacity in Patients with Heart Failure with Preserved Ejection Fraction
Palau, Patricia; Domínguez Mafé, Eloy; Núñez, Eduardo; Ramón, José María; López, Laura; Melero, Joana; Bellver, Alejandro; Chorro, Francisco J.; Bodí, Vicent; Bayes-Genis, Antoni; Sanchis, Juan; Núñez, Julio Elsevier (2017-06)Background Heart failure with preserved ejection fraction (HFpEF) is a clinical syndrome characterized by impaired exercise capacity resulting from dyspnea and fatigue. The pathophysiological mechanisms underlying the ... -
Inspiratory Muscle Training and Functional Electrical Stimulation for Treatment of Heart Failure With Preserved Ejection Fraction: Rationale and Study Design of a Prospective Randomized Controlled Trial
Palau, Patricia; Domínguez Mafé, Eloy; López, Laura; Heredia, Raquel; González, Jessika; Ramón, José María; Serra, Pilar; Santas, Enrique; Bodí, Vicent; Sanchis, Juan; Chorro, Francisco J.; Núñez, Julio Wiley (2016-08-02)Heart failure with preserved ejection fraction (HFpEF) has become the most prevalent form of heart failure in developed countries. Regrettably, there is no evidence-based effective therapy for HFpEF. We seek to evaluate ... -
Iron deficiency and short-term adverse events in patients with decompensated heart failure
Palau, Patricia; Llàcer, Pau; Domínguez Mafé, Eloy; Tormo, Juan Pablo; Zakarne, Rim; Mollar, Anna; Martínez, Ana; Miñana, Gema; Santas, Enrique; Almenar-Bonet, Luis; Fácila, Lorenzo; de la Espriella-Juan, Rafael; Núñez, Eduardo; Manzano, Luis; Bayes-Genis, Antoni; Núñez, Julio Springer (2021-03-15)Background: For patients with heart failure (HF), iron deficiency (ID) is a common therapeutic target. However, little is known about the utility of transferrin saturation (TSAT) or serum ferritin for risk stratification ... -
Isolated Partial Congenital Absence of the Pericardium: A Familial Presentation
Palau, Patricia; Domínguez Mafé, Eloy; García González, Pilar; Gallego Peris, Jorge; Bosch, María José; Sieso, Eduardo Elsevier (2015)Congenital defects of the pericardium are uncommon heart abnormalities. Most of the patients are asymptomatic and are usually diagnosed incidentally. Complications are more common in partial absence than in complete absence ... -
Los desafíos del profesorado clínico en la educación médica
Palau, Patricia; Domínguez Mafé, Eloy; Llueca, Antoni; Nuñez, Julio; Bertomeu-González, Vicente; Sanchez-Andres, Juan V.; Pallarés-Carratalá, Vicente Elsevier (2017-11-04)Background: There is a unique particularity of clinical teaching in medical education that isbeyond knowledge, skills or teaching methods of each clinician: this is clinical teaching context.This study aimed to analyze the ...