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Involvement of the beta-endorphin neurons of the hypothalamic arcuate nucleus in ethanol-induced place preference conditioning in mice
Pastor Medall, Raúl; Font Hurtado, Laura; MIQUEL, MARTA; Phillips, Tamara J.; González Aragón, Carlos Manuel Wiley (2011-10-20)Background: Increasing evidence indicates that mu- and delta-opioid receptors are decisively involved in the retrieval of memories underlying conditioned effects of ethanol. The precise mechanism by which these receptors ... -
Preclinical evidence implicating corticotropin-releasing factor signaling in ethanol consumption and neuroadaptation
Phillips, Tamara J.; Reed, Cheryl; Pastor Medall, Raúl John Wiley & Sons (2015)The results of many studies support the influence of the corticotropin-releasing factor (CRF) system on ethanol (EtOH) consumption and EtOH-induced neuroadaptations that are critical in the addiction process. This review ... -
Role of Corticotropin-Releasing Factor and Corticosterone in Behavioral Sensitization to Ethanol
Pastor Medall, Raúl; Reed, Cheryl; Meyer, Paul J.; McKinnon, Carrie; Ryabinin, Andrey E.; Phillips, Tamara J. American Society for Pharmacology and Experimental Therapeutics (2012)Neuroadaptations underlying sensitization to drugs of abuse seem to influence compulsive drug pursuit and relapse associated with addiction. Our previous data support a role for the corticotropin-releasing factor (CRF) ...