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Ara mostrant els elements 1-3 d 3
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Effects of the adenosine A2A antagonist KW 6002 (istradefylline) on pimozide-induced oral tremor and striatal c-Fos expression: comparisons with the muscarinic antagonist tropicamide
Betz, Adrienne J.; Vontell, Regina; Valenta, J.; Worden, Lila T.; Sink, Kelly S.; Font Hurtado, Laura; Correa, Merce; Sager, Thomas Nikolaj; Salamone, John Elsevier (2009-09)Typical antipsychotic drugs, including haloperidol and pimozide, have been shown to produce parkinsonian motor effects such as akinesia and tremor. Furthermore, there is an antagonistic interaction between adenosine A2A ... -
Intra-accumbens injections of the adenosine A(2A) agonist CGS 21680 affect effort-related choice behavior in rats
Stopper, Colin M.; Worden, Lila T.; Mingote, Susana; Port, Russell G.; Salamone, John; Font Hurtado, Laura; Pereira, Mariana; Farrar, Andrew M. Springer Verlag (2008)Rationale: Nucleus accumbens dopamine (DA) participates in the modulation of instrumental behavior, including aspects of behavioral activation and effort-related choice behavior. Rats with impaired accumbens DA transmission ... -
Nucleus Accumbens Adenosine A2A Receptors Regulate Exertion of Effort by Acting on the Ventral Striatopallidal Pathway
Font Hurtado, Laura; Mingote, Susana; Farrar, Andrew M.; Vontell, Regina; Worden, Lila T.; Stopper, Colin M.; Port, Russell G.; Sink, Kelly S.; Bunce, Jamie G.; Chrobak, James; Salamone, John Society for Neuroscience (2008)Goal-directed actions are sensitive to work-related response costs, and dopamine in nucleus accumbens is thought to modulate the exertion of effort in motivated behavior. Dopamine-rich striatal areas such as nucleus ...