Listar por autoría "9fc090f7-9d43-460e-a91d-5f99520b35ff"
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Amino acid change in the carbohydrate response element binding protein is associated with lower triglycerides and myocardial infarction incidence depending on level of adherence to the Mediterranean diet in the PREDIMED trial
CAROLINA, ORTEGA-AZORÍN; Sorlí, José V; Estruch, Ramon; Asensio, Eva Maria; Coltell, Oscar; González, José I.; Martínez González, Miguel Ángel; Ros, Emilio; Salas-Salvadó, Jordi; Fitó, Montserrat; Arós, Fernando; Lapetra, José; Serra-Majem, Lluis; Ruiz-Gutiérrez, Valentina; Gómez Gracia, Enrique; Fiol Ramis, Miquel; Flores, Gemma; Pintó, Xavier; Sáiz, Carmen; Ordovás Muñoz, José M.; Corella, Dolores American Heart Association (2014-02)Background: A variant (rs3812316, C771G, Gln241His) in the MLXIPL (Max-like protein X interacting protein-like) gene encoding the carbohydrate response element binding protein has been associated with lower triglycerides. ... -
Bitter, Sweet, Salty, Sour and Umami Taste Perception Decreases with Age: Sex-Specific Analysis, Modulation by Genetic Variants and Taste-Preference Associations in 18 to 80 Year-Old Subjects
Barragán-Arnal, Rocío; Coltell, Oscar; Portolés, Olga; Asensio, Eva Maria; Sorlí, José V; CAROLINA, ORTEGA-AZORÍN; González, José I.; Sáiz, Carmen; Fernández-Carrión, Rebeca; Ordovás Muñoz, José M.; Corella, Dolores MDPI (2018)There is growing interest in relating taste perception to diet and healthy aging. However, there is still limited information on the influence of age, sex and genetics on taste acuity as well as on the relationship between ... -
Crosstalk between smoking and the genome in older subjects with metabolic syndrome through genomics, epigenomics and transcriptomics
Coltell, Oscar; Asensio, Eva Maria; CAROLINA, ORTEGA-AZORÍN; Barragán-Arnal, Rocío; Sáiz, Carmen; Portolés, Olga; Sorlí, José V; Corella, Dolores European Molecular Biology Organization (EMBO) (2019-09-11)Tobacco smoking (Figure 1) is a major cause of cardiovascular diseases (CVD), and appears to have a multiplicative interaction with the other major CVD risk factors (lipids, hypertension, diabetes and others present in the ... -
Education modulates the association of the FTO rs9939609 polymorphism with body mass index and obesity risk in the Mediterranean population
Corella, Dolores; Carrasco, Paula; Sorlí, José V; Coltell, Oscar; CAROLINA, ORTEGA-AZORÍN; Guillen, Montserrat; González, José I.; Sáiz, Carmen; Estruch, Ramon; Ordovás Muñoz, José M. Elsevier (2012)Objective To define whether the rs9939609 FTO (fat mass and obesity associated) single nucleotide polymorphism (SNP) is associated with anthropometric measurements and its modulation by educational level in a Mediterranean ... -
Influence of the adherence to the Mediterranean diet on the effect of smoking on genomewide methylation among subjects with metabolic syndrome
Coltell, Oscar; Asensio, Eva Maria; CAROLINA, ORTEGA-AZORÍN; Sorlí, José V; González-Monje, Inma; Pascual, Eva C.; Portolés, Olga; Sáiz, Carmen; Corella, Dolores Heart Centre, University Hospital Halle (Saale) (2019-09-13)Tobacco smoking is an important risk factor for lung cancer, respiratory diseases and cardiovascular diseases, among others. Moreover, smoking can speed up the normal aging process of several tissues increasing the biological ... -
Novel association of the obesity risk-allele near Fas Apoptotic Inhibitory Molecule 2 (FAIM2) gene with heart rate and study of its effects on myocardial infarction in diabetic participants of the PREDIMED trial
Corella, Dolores; Sorlí, José V; González, José I.; CAROLINA, ORTEGA-AZORÍN; Fitó, Montserrat; Bulló, Mònica; Martínez González, Miguel Ángel; Ros, Emilio; Arós, Fernando; Lapetra, José; Gómez Gracia, Enrique; Serra-Majem, Lluis; Ruiz-Gutiérrez, Valentina; Fiol Ramis, Miquel; Coltell, Oscar; Vinyoles, Ernest; Pintó, Xavier; Martí, Amelia; Sáiz, Carmen; Ordovás Muñoz, José M.; Estruch, Ramon BioMed Central (2014-01)Background: The Fas apoptotic pathway has been implicated in type 2 diabetes and cardiovascular disease. Although a polymorphism (rs7138803; G > A) near the Fas apoptotic inhibitory molecule 2 (FAIM2) locus has been related ...