Listar por autoría "9b5e9d1b-188f-4920-b100-0cb99956c898"
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Alcohol Binge Drinking and Anxiety‐Like Behavior in Socialized Versus Isolated C57BL/6J Mice
Evans, Ophelia; Rodríguez Borillo, Olga; Font Hurtado, Laura; Currie, Paul J.; Pastor Medall, Raúl Wiley (2020-01)Background: Binge alcohol drinking has been characterized as a key feature of alcoholism. The drinking‐in‐the‐dark (DID) preclinical model, a procedure that promotes high levels of ethanol (EtOH) intake in short periods ... -
Effects of naltrexone on alcohol, sucrose, and saccharin binge-like drinking in C57BL/6J mice: a study with a multiple bottle choice procedure
Morales, Ileana; Rodríguez Borillo, Olga; Font Hurtado, Laura; Pastor Medall, Raúl Lippincott, Williams & Wilkins (2020-04)Chronic alcohol (ethyl alcohol, EtOH) binging has been associated with long-term neural adaptations that lead to the development of addiction. Many of the neurobiological features of EtOH abuse are shared with other forms ... -
Emotion elicitation during music listening: subjective self-reports, facial expression, and autonomic reactivity
Fuentes Sánchez, Nieves; Pastor Medall, Raúl; Escrig, Miguel A.; Elipe Miravet, Marcel; Pastor, M. Carmen Wiley Periodicals LLC (2021-06-18)The use of music as emotional stimuli in experimental studies has grown in recent years. However, prior studies have mainly focused on self-reports and central measures, with a few works exploring the time course of ... -
Ethanol drinking-in-the-dark facilitates behavioral sensitization to ethanol in C57BL/6J, BALB/cByJ, but not in mu-opioid receptor deficient CXBK mice
Tarragon Cros, Ernesto; Baliño, Pablo; González Aragón, Carlos Manuel; Pastor Medall, Raúl Elsevier (2012)Background: Neuroplasticity associated with drug-induced behavioral sensitization has been associated with excessive drug pursuit and consumption characteristic of addiction. Repeated intraperitoneal (ip) injections of ... -
Individual differences in music reward sensitivity influence the perception of emotions represented by music
Fuentes Sánchez, Nieves; Pastor, M. Carmen; Eerola, Tuomas; Pastor Medall, Raúl SAGE Publications (2021-12-15)Although music is one of the most important sources of pleasure for many people, there are considerable individual differences in music reward sensitivity. Behavioral and neurobiological characterizations of music reward ... -
Intracellular calcium chelation with BAPTA-AM modulates ethanol-induced behavioral effects in mice
Baliño, Pablo; Monferrer Sales, Lidón; Pastor Medall, Raúl; González Aragón, Carlos Manuel Elsevier (2012)Calcium (Ca2+) has been characterized as one of the most ubiquitous, universal and versatile intracellular signaling molecules responsible for controlling numerous cellular processes. Ethanol-induced effects on Ca2+ ... -
Involvement of the beta-endorphin neurons of the hypothalamic arcuate nucleus in ethanol-induced place preference conditioning in mice
Pastor Medall, Raúl; Font Hurtado, Laura; MIQUEL, MARTA; Phillips, Tamara J.; González Aragón, Carlos Manuel Wiley (2011-10-20)Background: Increasing evidence indicates that mu- and delta-opioid receptors are decisively involved in the retrieval of memories underlying conditioned effects of ethanol. The precise mechanism by which these receptors ... -
Involvement of the endogenous opioid system in the psychopharmacological actions of ethanol: the role of acetaldehyde
Font Hurtado, Laura; Luján Pérez, Miguel Ángel; Pastor Medall, Raúl Frontiers Media (2013)Significant evidence implicates the endogenous opioid system (EOS) (opioid peptides and receptors) in the mechanisms underlying the psychopharmacological effects of ethanol. Ethanol modulates opioidergic signaling and ... -
Musical preference but not familiarity influences subjective ratings and psychophysiological correlates of music-induced emotions
Sánchez Fuentes, Nieves; Pastor Medall, Raúl; Eerola, Tuomas; Escrig, Miguel A.; Pastor, M. Carmen Elsevier (2022-07)Listening to music prompts strong emotional reactions in the listeners but relatively little research has focused on individual differences. This study addresses the role of musical preference and familiarity on emotions ... -
Neural correlates of cocaine-induced conditioned place preference in the posterior cerebellar cortex
Rodríguez Borillo, Olga; Roselló-Jiménez, Lorena; Guarque-Chabrera, Julian; Palau-Batet, María; Gil-Miravet, Isis; Pastor Medall, Raúl; MIQUEL, MARTA; Font Hurtado, Laura Frontiers Media (2023)Introduction: Addictive drugs are potent neuropharmacological agents capable of inducing long-lasting changes in learning and memory neurocircuitry. With repeated use, contexts and cues associated with consumption can ... -
Opioidergic and dopaminergic modulation of cost/benefit decision-making in Long Evans Rats
Morales, Ileana; Currie, Paul J.; Hackenberg, Timothy D.; Pastor Medall, Raúl Elsevier (2017)Eating disorders are associated with impaired decision-making and dysfunctional reward-related neurochemistry. The present study examined the potential contributions of dopamine and opioid signaling to these processes using ... -
Participation of L-type calcium channels in ethanol-induced behavioral stimulation and motor incoordination: Effects of diltiazem and verapamil
Baliño, Pablo; Pastor Medall, Raúl; González Aragón, Carlos Manuel Elsevier (2010-06)Calcium flux through voltage gate calcium channels (VGCC) is involved in many neuronal processes such as membrane depolarization, gene expression, hormone secretion, and neurotransmitter release. Several studies have shown ... -
Preclinical evidence implicating corticotropin-releasing factor signaling in ethanol consumption and neuroadaptation
Phillips, Tamara J.; Reed, Cheryl; Pastor Medall, Raúl John Wiley & Sons (2015)The results of many studies support the influence of the corticotropin-releasing factor (CRF) system on ethanol (EtOH) consumption and EtOH-induced neuroadaptations that are critical in the addiction process. This review ... -
Putting forward a model for the role of the cerebellum in cocaine-induced pavlovian memory
Melchor Eixea, Ignasi; Guarque-Chabrera, Julian; Sánchez Hernández, Aitor; Ibáñez-Marín, Patricia; Pastor Medall, Raúl; MIQUEL, MARTA Frontiers Media (2023)Substance Use Disorder (SUD) involves emotional, cognitive, and motivational dysfunction. Long-lasting molecular and structural changes in brain regions functionally and anatomically linked to the cerebellum, such as the ... -
Role of Corticotropin-Releasing Factor and Corticosterone in Behavioral Sensitization to Ethanol
Pastor Medall, Raúl; Reed, Cheryl; Meyer, Paul J.; McKinnon, Carrie; Ryabinin, Andrey E.; Phillips, Tamara J. American Society for Pharmacology and Experimental Therapeutics (2012)Neuroadaptations underlying sensitization to drugs of abuse seem to influence compulsive drug pursuit and relapse associated with addiction. Our previous data support a role for the corticotropin-releasing factor (CRF) ... -
Separate Contribution of Striatum Volume and Pitch Discrimination to Individual Differences in Music Reward
Hernández, Mireia; Palomar-García, María-Ángeles; Nohales Nieto, Benito; Olcina-Sempere, Gustau; Villar-Rodríguez, Esteban; Pastor Medall, Raúl; Avila, Cesar; Parcet, Maria Antonia SAGE Publications (2019)Individual differences in the level of pleasure induced by music have been associated with the response of the striatum and differences in functional connectivity between the striatum and the auditory cortex. In this ... -
Spanish adaptation of a film music stimulus set (FMSS): Cultural and gender differences in the perception of emotions prompted by music excerpts
Fuentes Sánchez, Nieves; Pastor Medall, Raúl; Eerola, Tuomas; Pastor, M. Carmen SAGE Publications (2020)The literature review reveals different conceptual and methodological challenges in the field of music and emotion, such as the lack of agreement in terms of standardized datasets, and the need for replication of prior ... -
The MAO-A inhibitor clorgyline reduces ethanol-induced locomotion and its volitional intake in mice
Ledesma Llorente, Juan Carlos; Escrig, Miguel A.; Pastor Medall, Raúl; González Aragón, Carlos Manuel Elsevier (2014)Hydrogen peroxide is the co-substrate used by the enzyme catalase to form Compound I (the catalase–H2O2 system), which is the major pathway for the conversion of ethanol (EtOH) into acetaldehyde in the brain. This acetaldehyde ...