Listar por autoría "92b5bb89-cbbe-4121-9051-be12dfb74e46"
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A comparative study of the protein levels of Insulin and IGF-1 receptors and receptor substrates in a rat model of development and agind in different brain areas
García Díaz, Cristina Universitat Jaume I (2016-07-21)Alzheimer’s disease (AD) is one of the most common causes of dementia. AD is a progressive, degenerative, and irreversible neurological disorder that cause early, cognitive impairment, memory loss, and behaviour changes. ... -
Central relaxin-3 receptor (RXFP3) activation impairs social recognition and modulates ERK-phosphorylation in specific GABAergic amygdala neurons
Albert Gasco, Hector; Sánchez-Sarasúa, Sandra; Ma, Sherie; García Díaz, Cristina; Gundlach, Andrew Lawrence; Sánchez-Pérez, Ana María; Olucha-Bordonau, Francisco E Springer (2019-01)In mammals, the extended amygdala is a neural hub for social and emotional information processing. In the rat, the extended amygdala receives inhibitory GABAergic projections from the nucleus incertus (NI) in the pontine ... -
IRS1 expression in hippocampus is age-dependent and is required for mature spine maintenance and neuritogenesis
Sánchez-Sarasúa, Sandra; Meseguer Beltrán, Maria; García Díaz, Cristina; Beltrán-Bretones, Maria Teresa; ElMlili, Nisrin; Sánchez-Pérez, Ana María Elsevier (2022-01)Insulin and insulin-like growth factor type I (IGF-1) play prominent roles in brain activity throughout the lifespan. Insulin/IGF1 signaling starts with the activation of the intracellular insulin receptor substrates (IRS). ... -
Nucleus incertus ablation disrupted conspecific recognition and modified immediate early gene expression patterns in ‘social brain’ circuits of rats
García Díaz, Cristina; Sánchez-Catalán, María José; Castro-Salazar, E.; García Avilés, Álvaro; Albert Gasco, Hector; Sánchez-Sarasúa, Sandra; Sánchez-Pérez, Ana María; Gundlach, Andrew Lawrence; Olucha-Bordonau, Francisco E Elsevier (2019-01-01)Social interaction involves neural activity in prefrontal cortex, septum, hippocampus, amygdala and hypothalamus. Notably, these areas all receive projections from the nucleus incertus (NI) in the pontine tegmentum. ... -
Un nuevo agente en los mecanismos de la adicción al alcohol y la ingesta: el núcleo incertus y el neuropéptido relaxina-3
Nova Marqués, José Antonio; García Díaz, Cristina; Olucha-Bordonau, Francisco E Viguera Editores (2018)La ingesta de alcohol está facilitada por la relación con la conducta alimentaria, y ambas conductas están altamente influidas por situaciones de estrés y ansiedad. La desregulación de estos procesos puede llegar a ... -
El potencial evocado P3 como un marcador neurobiológico de la psicopatía
García Díaz, Cristina Universitat Jaume I (2015-07-21)The present literature review is aimed to examine the relation between P3 brain potential responses as neurobiological marker of psychopathy. We conducted meta-analysis of 8 studies (N=1528) focused to investigate the ... -
Relaxin-3 Innervation From the Nucleus Incertus to the Parahippocampal Cortex of the Rat
García Díaz, Cristina; Gil-Miravet, Isis; Albert Gasco, Hector; Mañas-Ojeda, Aroa; Ros Bernal, Francisco; Castillo-Gómez, Esther; Gundlach, Andrew Lawrence; Olucha-Bordonau, Francisco E Frontiers Media (2021)Spatial learning and memory processes depend on anatomical and functional interactions between the hippocampus and the entorhinal cortex. A key neurophysiological component of these processes is hippocampal theta rhythm, ...