Listar por autoría "789dc5ac-a9df-4aa6-ac08-12e4ad97b81d"
Mostrando ítems 1-16 de 16
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Childhood abuse in the etiological continuum underlying psychosis from first-episode psychosis to psychotic experiences
Elsevier (2015)Goal The present study aimed to examine the prevalence of child abuse across the continuum of psychosis. Patients and methods The sample consisted of 198 individuals divided in three groups: (1) 48 FEP patients, ... -
Childhood abuse, the BDNF-Val66Met polymorphism and adult psychotic-like experiences
The Royal College of Psychiatrists (2011)Individuals exposed to childhood abuse are more likely to report positive psychotic-like experiences. Met carriers reported more positive psychotic-like experiences when exposed to childhood abuse than did individuals ...
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Childhood trauma and the rs1360780 SNP of FKBP5 gene in psychosis: a replication in two general population samples
Cambridge University Press (2016)FKBP5 gene interacts with childhood trauma in the risk for several stress-related psychiatric disorders including subclinical psychosis. The present study examined whether variation at the rs1360780 SNP of FKBP5 gene ...
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Early adversity and 5-HTT-BDNF genes: new evidences of gene-environment interactions on depressive symptoms in a general population
Cambridge University Press (2009-09)Adverse childhood experiences have been described as one of the major environmental risk factors for depressive disorder. Likewise, the deleterious impact of early traumatic experiences on depression seems to be moderated ...
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Evidence of an epistatic effect between Dysbindin-1 and Neuritin-1 genes on the risk for schizophrenia spectrum disorders
Elsevier (2017-02)Background The interest in studying gene–gene interactions is increasing for psychiatric diseases such as schizophrenia-spectrum disorders (SSD), where multiple genes are involved. Dysbindin-1 (DTNBP1) and Neuritin-1 ... -
Five-factor model and internalizing and externalizing syndromes: 4 A 5-year prospective study
Elsevier (2015)The main aim of the present research was to study the prospective relationships of the five-factor model of personality and the internalizing and externalizing suprafactors of psychopathology. A sample of 323 young adults ...
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Involvement of NRN1 gene in schizophrenia-spectrum and bipolar disorders and its impact on age at onset and cognitive functioning
Taylor & Francis (2016)Objectives Neuritin 1 gene (NRN1) is involved in neurodevelopment processes and synaptic plasticity and its expression is regulated by brain-derived neurotrophic factor (BDNF). We aimed to investigate the association of ...
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Psychometric properties of drinking motives questionnaire-revised (DMQ-R) in Spanish adolescents
Hogrefe (2016)The Drinking Motives Questionnaire-Revised (DMQ-R; Cooper, 1994) is the most widely used questionnaire to assess drinking motives. This research aimed to adapt and study the validity and reliability of the Spanish DMQ-R ...
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Psychosis-inducing effects of cannabis are related to both childhood abuse and COMT genotypes
Wiley (2014-01)OBJECTIVE: To test whether the association between childhood abuse, cannabis use and psychotic experiences (PEs) was moderated by the COMT (catechol-O-methyltransferase) gene. METHOD: Psychotic experiences (PEs), ...
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Putative role of the COMT gene polymorphism (Val158Met) on verbal working memory functioning in a healthy population
John Wiley & Sons (2008)Working memory has been described as a neurocognitive probe of prefrontal brain functioning. Genetic variability related with catechol-O-methyltransferase (COMT) gene (Val158Met polymorphism) has received increasing attention ...
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Season of birth and subclinical psychosis: systematic review and meta-analysis of new and existing data (Review)
Elsevier (2015)Season of birth (SOB) has been shown to modify the risk of several health outcomes, including a number of neuropsychiatric disorders. Empirical evidence indicates that subclinical forms of psychosis in the general population ...
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Stressful life events during adolescence and risk for externalizing and internalizing psychopathology: a meta-analysis
Springer (2017-12)The main objective of the present research was to analyze the relations between stressful life events and the externalizing and internalizing spectra of psychopathology using meta-analytical procedures. After removing the ...
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The effect of the AKT1 gene and cannabis use on cognitive performance in healthy subjects
Sage (2020-06-13)Background: Evidence suggests that the AKT1 gene may modulate the degree to which cannabis use induces cognitive alterations in patients with a psychotic disorder. Aim: To examine the interplay between AKT1 and cannabis ...
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The interaction between the ZNF804A gene and cannabis use on the risk of psychosis in a non-clinical sample
Elsevier (2019)The ZNF804A gene and cannabis use are risk factors for psychosis and both have also been associated with schizotypal traits. This study aimed to investigate: i) the association of lifetime cannabis use (and its dose ...
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The role of genetic variability in the GABRA6, 5-HTT and BDNF genes in anxiety-related traits
Wiley-Blackwell (2012-03)Objective: The aims of this study were to test the individual association of the serotonin transporter gene (SLC6A4), the brain-derived neurotrophic factor gene (BDNF) and the GABAAα6 receptor subunit gene (GABRA6) with ...
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Violent aggression predicted by multiple pre-adult environmental hits
Nature Publishing Group (2018)Early exposure to negative environmental impact shapes individual behavior and potentially contributes to any mental disease. We reported previously that accumulated environmental risk markedly decreases age at schizophrenia ...
