• closedAccess   Association between exposure to organochlorine compounds and maternal thyroid status: Role of the iodothyronine deiodinase 1 gene 

      Llop, Sabrina; Murcia, Mario; Álvarez Pedrerol, Mar; Grimalt, Joan O.; SANTA MARINA, LORETO; Julvez, Jordi; Goñi-Irigoyen, Fernando; Espada, Mercedes; Ballester, Ferran; Rebagliato, Marisa; López Espinosa, María José Elsevier (2017-04-08)
      Introduction: Exposure to organochlorine compounds (OCs) may interfere with thyroid hormone (TH) homeostasis. The disruption of the deiodinase (DIO) enzymes has been proposed as a mechanism of action. Aim: To evaluate ...
    • openAccess   Association between the Use of Folic Acid Supplements during Pregnancy and Children's Cognitive Function at 7-9 Years of Age in the INMA Cohort Study 

      Compañ Gabucio, Laura M; Torres-Collado, Laura; Garcia de la Hera, Manuela; Fernández Somoano, Ana; Tardon, Adonina; Julvez, Jordi; Sunyer Deu, Jordi; Rebagliato, Marisa; Murcia, Mario; Ibarluzea, Jesus; SANTA MARINA, LORETO; Vioque, Jesus MDPI (2022-09-25)
      This study investigated the association between maternal low (<400 μg/day) or high (≥1000 μg/day) folic acid supplements (FAs) use during pregnancy and the attentional function and working memory in boys and girls at age ...
    • closedAccess   Comparison of urinary iodine levels in women of childbearing age during and after pregnancy 

      Castilla, Ane M.; Murcia, Mario; Arrizabalaga, Juan José; Espada, Mercedes; Julvez, Jordi; Basterretxea, Mikel; Álvarez Pedrerol, Mar; Estarlich, Marisa; Moreno, Elena; Guxens, Mònica; Vioque, Jesus; Rebagliato, Marisa Springer (2018-08)
      Purpose Median urinary iodine concentration (UIC) is used to describe the iodine status of a population. However, the link between UIC and iodine intake may vary during pregnancy. The aim of this study was to compare ...
    • openAccess   Dietary intake in pregnant women in a Spanish Mediterranean area: as good as it is supposed to be? 

      Rebagliato, Marisa; Ramón, Rosa; Murcia, Mario; Navarrete-Muñoz, Eva María; Vioque, Jesus; Ballester, Ferran; Rodríguez-Bernal, Clara L.; Quiles, Joan Cambridge University Press (2013-08)
      Objective To assess food and nutrient intakes and compliance with nutritional recommendations in pregnant women according to selected sociodemographic characteristics. Design Cross-sectional study based on data from the ...
    • openAccess   Distributions and determinants of urinary biomarkers of organophosphate pesticide exposure in a prospective Spanish birth cohort study 

      Llop, Sabrina; Murcia, Mario; Íñiguez, Carmen; Roca, Marta; González, Llúcia; Yusà, Vicent; Rebagliato, Marisa; Ballester, Ferran BioMed Central (2017)
      Background: Prenatal exposure to organophosphate pesticides (OPs) has been associated with impaired child development. Pesticide exposure determinants need to be studied in order to identify sources and pathways of pesticide ...
    • openAccess   Exploration of thyroglobulin as a biomarker of iodine status in iodine-sufficient and mildly iodine-deficient pregnant women 

      Dineva, Mariana; Rayman, Margaret; Levie, Deborah; Hunziker, Sandra; Guxens, Mònica; Peeters, Robin; Murcia, Mario; Rebagliato, Marisa; Irizar Loibide, Amaia; Jimeno-Romero, Alba; Sunyer Deu, Jordi; Korevaar, Tim; Bath, Sarah Springer (2023-03-27)
      Purpose Urinary iodine-to-creatinine ratio (UI/Creat) reflects recent iodine intake but has limitations for assessing habitual intake. Thyroglobulin (Tg) concentration, which increases with thyroid size, appears to be an ...
    • openAccess   Exposure to mercury among 9-year-old children and neurobehavioural function 

      Lozano, Manuel; Murcia, Mario; Soler-Blasco, Raquel; González Llúcia; Iriarte, Gorka; Rebagliato, Marisa; Lopez-Espinosa, Maria-Jose; Esplugues Cebrián, Ana; Ballester, Ferran; Llop, Sabrina Elsevier (2020-10-20)
      Mercury (Hg) is an environmental neurotoxicant whose main route of exposure in humans is the consumption of seafood. The aim of this study was to explore the relationship between Hg exposure at 9 years old and behaviour ...
    • closedAccess   Exposure to mercury among Spanish preschool children: Trend from birth to age four 

      Llop, Sabrina; Murcia, Mario; Aguinagalde, Xabier; Vioque, Jesus; Rebagliato, Marisa; Cases, Amparo; Iñiguez, Carmen; López Espinosa, María José; Amurrio, Ascensión; Navarrete-Muñoz, Eva María; Ballester, Ferran Elsevier (2014)
      The purpose of this study is to describe the total hair mercury concentrations and their determinants in preschool Spanish children, as well as to explore the trend in mercury exposure from birth to the age four. This ...
    • closedAccess   Factors associated with second-hand smoke exposure in non-smoking pregnant women in Spain: Self-reported exposure and urinary cotinine levels 

      Aurrekoetxea, J. J.; Murcia, Mario; Rebagliato, Marisa; Fernández Somoano, Ana; Miren Castlla, Ane; Guxens, Mònica; López Espinosa, María José; Lertxundi, Aitana; Espada, Mercedes; Tardon, Adonina; Ballester, Ferran; SANTA MARINA, LORETO Elsevier (2014-02)
      The aim of this study was to evaluate the main sources of and sociodemographic factors associated with second-hand smoke (SHS) exposure, assessed both by questionnaire and by urinary cotinine (UC) levels, in non-smoking ...
    • closedAccess   High doses of folic acid in the periconceptional period and risk of low weight for gestational age at birth in a population based cohort study. 

      Navarrete-Muñoz, Eva María; Valera-Gran, Desirée; Garcia de la Hera, Manuela; González-Palacios, Sandra; Riaño-Galan, Isolina; Murcia, Mario; Lertxundi, Aitana; Guxens, Mònica; Tardon, Adonina; Amiano, Pilar; Vrijheid, Martine; Rebagliato, Marisa; Vioque, Jesus Springer (2019)
      Purpose We investigated the association between maternal use of folic acid (FA) during pregnancy and child anthropometric measures at birth. Methods We included 2302 mother–child pairs from a population-based birth cohort ...
    • closedAccess   Iodine Supplementation During Pregnancy and Infant Neuropsychological: INMA Mother and Child Cohort Study 

      Rebagliato, Marisa; Murcia, Mario; Álvarez Pedrerol, Mar; Espada, Mercedes; Fernández Somoano, Ana; Lertxundi, Nerea; Navarrete-Muñoz, Eva María; Forns, Joan; Aranbarri, Aritz; Llop, Sabrina; Julvez, Jordi; Tardon, Adonina; Ballester, Ferran Oxford University Press (2013-04)
      Iodine supplementation during pregnancy is a common practice in developed countries. However, scant evidence is available regarding the safety and effectiveness of maternal iodine supplementation with regard to child ...
    • closedAccess   Maternal copper status and neuropsychological development in infants and preschool children 

      Amorós Salvador, Rubén; Murcia, Mario; González, Llúcia; Soler-Blasco, Raquel; Rebagliato, Marisa; Iñiguez, Carmen; Carrasco, Paula; Vioque, Jesus; Broberg, Karin; Levi, Michael; López Espinosa, María José; Ballester, Ferran; Llop, Sabrina Elsevier (2019-04)
      Introduction Copper (Cu) is an essential element involved in biological processes; however, excessive Cu could be harmful because of its reactive nature. Very few studies have evaluated its potential neurotoxic effects. ...
    • closedAccess   Maternal pre-pregnancy overweight and obesity, and child neuropsychological development: two Southern European birth cohort studies 

      Casas, Maribel; Chatzi, Leda; Carsi, Anne-Elie; Amiano, Pilar; Guxens, Mònica; Kogevinas, Manolis; Koutra, Katerina; Lertxundi, Nerea; Murcia, Mario; Rebagliato, Marisa; Riaño, Isolina; Rodríguez-Bernal, Clara L.; Roumeliotaki, Theano; Sunyer Deu, Jordi; Mendez, Michelle; Vrijheid, Martine International Epidemiological Association (2013)
      Background Maternal pre-pregnancy obesity may be associated with impaired infant neuropsychological development; however, there are few studies and it is unclear if reported associations are due to intrauterine ...
    • closedAccess   Maternal Smoking During Pregnancy and Fetal Biometry: The INMA Mother and Child Cohort Study 

      Iñiguez, Carmen; Ballester, Ferran; Costa, Olga; Murcia, Mario; Souto, Ana; SANTA MARINA, LORETO; Aurrekoetxea, J. J.; Espada, Mercedes; Vrijheid, Martine; Álvarez Avellón, Sara M.; Álvarez Pedrerol, Mar; Rebagliato, Marisa Oxford University Press (2013-10-01)
      In utero tobacco exposure has been associated with fetal growth restriction, but uncertainty remains about critical windows of exposure and specific effects on body segments. In the present study, we aimed to examine the ...
    • closedAccess   Maternal Thyroid Dysfunction during Gestation, Preterm Delivery, and Birthweight. The Infancia y Medio Ambiente Cohort, Spain 

      León, Gemma; Murcia, Mario; Rebagliato, Marisa; Álvarez Pedrerol, Mar; Castilla, Ane M.; Basterretxea, Mikel; Iñiguez, Carmen; Fernández Somoano, Ana; Blarduni, Elizabeth; Foradada, Carles M.; Tardon, Adonina; Vioque, Jesus Wiley (2015)
      Background: Maternal clinical thyroid disorders can cause reproductive complications. However, the effects ofmild thyroid dysfunctions are not yet well established. The aim was to evaluate the association of maternal ...
    • closedAccess   Mediators of the association between maternal body mass index and breastfeeding duration in 3 international cohorts 

      Keyes, Madeline; Andrews, Chloe; Midya, Vishal; Carrasco, Paula; Guxens, Mònica; Jimeno-Romero, Alba; Murcia, Mario; Rodriguez-Dehli, Cristina; Romaguera, Dora; Santa-Maria, Loreto; Vafeiadi, Marina; Chatzi, Lida; Oken, Emily; Vrijheid, Martine; Valvi, Damaskini; Sen, Sarbattama Elsevier (2023-07)
      Background: Maternal obesity has been associated with shorter breastfeeding duration, but little is known about mediating factors explaining this association. It is important to assess these relationships across diverse ...
    • openAccess   Polymorphisms in ABC Transporter Genes and Concentrations of Mercury in Newborns – Evidence from Two Mediterranean Birth Cohorts 

      Llop, Sabrina; Engström, Karin; Ballester, Ferran; Franforte, Elisa; Alhamdow, Ayman; Pisa, Federica; Tratnik, Janja Snoj; Mazej, Datja; Murcia, Mario; Rebagliato, Marisa; Bustamante, Mariona; Sunyer Deu, Jordi; Sofianou-Katsoulis, Aikaterini; Prasouli, Alexia; Antonopoulou, Eleni; Antoniadou, Ioanna; Nakou, Sheena; Barbone, Fabio; Horvat, Milena; Broberg, Karin Public Library of Science (2014)
      Background: The genetic background may influence methylmercury (MeHg) metabolism and neurotoxicity. ATP binding cassette (ABC) transporters actively transport various xenobiotics across biological membranes. Objective: ...
    • openAccess   Postnatal exposure to mercury and neuropsychological development among preschooler children 

      Llop, Sabrina; Murcia, Mario; Amorós Salvador, Rubén; Julvez, Jordi; SANTA MARINA, LORETO; Soler-Blasco, Raquel; Rebagliato, Marisa; Iñiguez, Carmen; Aguinagalde, Xabier; Iriarte, Gorka; Lopez-Espinosa, Maria-Jose; Andiarena, Ainara; Gonzalez, Llúcia; Vioque, Jesus; Sunyer Deu, Jordi; Ballester, Ferran Springer (2020-03-13)
      The objective of this study was to describe the postnatal exposure to Hg and to evaluate its association with neuropsychological development among preschool children. The study population are 4–5 years old children (n = ...
    • openAccess   Poverty, social exclusion, and mental health: the role of the family context in children aged 7–11 years INMA mother‑and‑child cohort study 

      González, Llúcia; Estarlich, Marisa; Murcia, Mario; BARRETO-ZARZA, FLORENCIA; SANTA MARINA, LORETO; Simo, Sandra; Larranaga, Maria Isabel; Ruiz-Palomino, Estefania; Ibarluzea, Jesus; Rebagliato, Marisa Springer (2023)
      Mental health problems are common in childhood and tend to be more frequent in populations at risk of poverty or social exclusion (AROPE). The family environment can play a role in reducing the impact of economic hardship ...
    • openAccess   Pre and postnatal exposure to mercury and respiratory health in preschool children from the Spanish INMA Birth Cohort Study 

      Carrasco, Paula; Estarlich, Marisa; Iñiguez, Carmen; Ferrero, Amparo; Murcia, Mario; Esplugues Cebrián, Ana; Vioque, Jesus; SANTA MARINA, LORETO; Zabaleta, Carlos; Iriarte, Gorka; Fernández Somoano, Ana; Tardon, Adonina; Vrijheid, Martine; Sunyer Deu, Jordi; Ballester, Ferran; Llop, Sabrina Elsevier (2021)
      Effects of mercury on maturing immune system have been reported, however the association with respiratory and allergy problems during infancy remains unclear. The aim of this study is to evaluate the association between ...