• closedAccess   Chronic Cocaine Effects in Retinal Metabolism and Electrophysiology: Treatment with Topiramate 

      Sánchez-Villarejo, María V.; López-Pedrajas, Rosa; Sánchez Vallejo, Violeta; Genovés, José M.; Muriach Saurí, María; Barcia, Jorge M; Romero, Francisco J. Informa Healthcare (2014)
      Purpose: Cocaine abuse is a major public health problem with multiple-related complications. Indeed, cocaine can affect almost every organ of the human body, but little is known about its effects on the visual system. The ...
    • openAccess   Cocaine promotes oxidative stress and microglial-macrophage activation in rat cerebellum 

      López-Pedrajas, Rosa; Ramírez Lamelas, Dolores T.; Muriach, Borja; Sánchez-Villarejo, María V.; Almansa, Inmaculada; Vidal Gil, Lorena; Romero, Francisco J.; Barcia, Jorge M; Muriach Saurí, María Frontiers Media (2015)
      Different mechanisms have been suggested for cocaine neurotoxicity, including oxidative stress alterations. Nuclear factor kappa B (NF-κB), considered a sensor of oxidative stress and inflammation, is involved in drug ...
    • openAccess   Differential hippocampal response to chronic alcohol consumption of young adult and mature adult rats 

      Barcia, Jorge M; Sánchez-Villarejo, María V.; Almansa, Inmaculada; López-Pedrajas, Rosa; Muriach Saurí, María; Romero Gómez, Francisco Javier Oxford University Press (2012-05)
      AIMS Early ethanol consumption could be a risk factor for young brain integrity and its maturation, and also for the development of addictive behaviors in adulthood. Neuronal nitric oxide synthase (nNOS) expressing neurons ...
    • openAccess   Role of hippocampal NF-κB and GluN2B in the memory acquisition impairment of experiences gathered prior to cocaine administration in rats 

      López-Pedrajas, Rosa; Almansa, Inmaculada; Sánchez-Villarejo, María V.; Muriach, Borja; Barcia, Jorge M.; Romero, Francisco J; Muriach, Maria Nature Research (2021-10-08)
      Cocaine can induce severe neurobehavioral changes, among others, the ones involved in learning and memory processes. It is known that during drug consumption, cocaine-associated memory and learning processes take place. ...