Listar por autoría "4999fc1b-a21c-4b16-b61c-127d9bb0da16"
Mostrando ítems 1-20 de 21
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Biochemical and behavioral consequences of ethanol intake in a mouse model of metabolic syndrome
Baliño, Pablo; Romero Cano, Ricard; Muriach, Maria MDPI (2021-01-15)Ethanol abuse is a common issue in individuals with sedentary lifestyles, unbalanced diets, and metabolic syndrome. Both ethanol abuse and metabolic syndrome have negative impacts on the central nervous system, with ... -
Centrally formed acetaldehyde mediates ethanol-induced brain PKA activation
Tarragon Cros, Ernesto; Baliño, Pablo; González Aragón, Carlos Manuel Elsevier (2014)Centrally formed acetaldehyde has proven to be responsible for several psychopharmacological effects induced by ethanol. In addition, it has been suggested that the cAMP-PKA signaling transduction pathway plays an important ... -
Cytokines and chemokines as biomarkers of ethanol-induced neuroinflammation and anxiety-related behavior: Role of TLR4 and TLR2
Pascual, María; Baliño, Pablo; González Aragón, Carlos Manuel; Guerri, Consuelo Springer (2015)Recent evidence supports the influence of neuroimmune system activation on behavior. We have demonstrated that ethanol activates the innate immune system by stimulating toll-like receptor 4 (TLR4) signaling in glial cells, ... -
Dantrolene blockade of ryanodine receptor impairs ethanol-induced behavioral stimulation, ethanol intake and loss of righting reflex
Tarragon Cros, Ernesto; Baliño, Pablo; González Aragón, Carlos Manuel Elsevier (2012-08)Calcium has been characterized as one of the most ubiquitous, universal and versatile intracellular signals. Among other substances with the ability to alter intracellular calcium levels, ethanol has been described as ... -
Effects of Acute Ethanol Administration on Brain Oxidative Status: The Role of Acetaldehyde
Baliño, Pablo; Romero Cano, Ricard; Sanchez-Andres, Juan V.; Valls, Victoria; González Aragón, Carlos Manuel; Muriach, Maria Wiley (2019-08)Background: Ethanol (EtOH), one of the most widely consumed substances of abuse, can induce brain damage and neurodegeneration. EtOH is centrally metabolized into acetaldehyde, which has been shown to be responsible for ... -
Ethanol drinking-in-the-dark facilitates behavioral sensitization to ethanol in C57BL/6J, BALB/cByJ, but not in mu-opioid receptor deficient CXBK mice
Tarragon Cros, Ernesto; Baliño, Pablo; González Aragón, Carlos Manuel; Pastor Medall, Raúl Elsevier (2012)Background: Neuroplasticity associated with drug-induced behavioral sensitization has been associated with excessive drug pursuit and consumption characteristic of addiction. Repeated intraperitoneal (ip) injections of ... -
Evaluation of the inflammatory responses to sol–gel coatingswith distinct biocompatibility levels
Cerqueira, Andreia; Araújo-Gomes, Nuno; Zhang, Yang; van den Beucken, Jeroen; Martínez Ramos, Cristina; ozturan, seda; Izquierdo Escrig, Raul; Muriach, Maria; Romero Cano, Ricard; Baliño, Pablo; Romero-Gavilán, Francisco J John Wiley and Sons (2021-02-20)The immune system plays a crucial role in determining the implantation outcome, and macrophages are in the frontline of the inflammatory processes. Further, cellular oxidative stress resulting from the material recognition ... -
Human Milk Antioxidative Modifications in Mastitis: Further Beneficial Effects of Cranberry Supplementation
Valls-Bellés, Victoria; Abad, Cristina; HERNANDEZ-AGUILAR, MARIA-TERESA; Nacher, Amalia; Guerrero, Carlos; Baliño, Pablo; Romero, Francisco J; Muriach, Maria MDPI (2022)Mastitis is the inflammation of one or several mammal lobes which can be accompanied by a mammary gland infection, and is the leading cause of undesired early weaning in humans. However, little information exists regarding ... -
Impact of Plasma Oxidative Stress Markers on Post-race Recovery in Ultramarathon Runners: A Sex and Age Perspective Overview
Guerrero, Carlos; Collado-Boira, Eladio; MARTINEZ-NAVARRO, IGNACIO; Hernando, Barbara; Hernando, Carlos; Baliño, Pablo; Muriach, Maria MDPI (2021-03)Oxidative stress has been widely studied in association to ultra-endurance sports. Although it is clearly demonstrated the increase in reactive oxygen species and free radicals after these extreme endurance exercises, the ... -
Impact of TLR4 on behavioral and cognitive dysfunctions associated with alcohol-induced neuroinflammatory damage
Pascual, María; Baliño, Pablo; Alfonso Loeches, Silvia; González Aragón, Carlos Manuel; Guerri, Consuelo Elsevier (2011-06-01)Toll-like receptors (TLRs) play an important role in the innate immune response, and emerging evidence indicates their role in brain injury and neurodegeneration. Our recent results have demonstrated that ethanol is capable ... -
In Vivo Study of Ethanol-Activated Brain Protein Kinase A: Manipulations of Ca2+ Distribution and Flux
Baliño, Pablo; Ledesma Llorente, Juan Carlos; González Aragón, Carlos Manuel Wiley (2014-03)Background The cAMP-dependent protein kinase (PKA) signaling transduction pathway has been shown to play an important role in the modulation of several ethanol (EtOH)-induced behavioral actions. In vivo, short-term ... -
Influence of Female Sex Hormones on Ultra-Running Performance and Post-Race Recovery: Role of Testosterone
Collado-Boira, Eladio; Baliño, Pablo; Boldo-Roda, Ana; MARTINEZ-NAVARRO, IGNACIO; Hernando, Barbara; Recacha-Ponce, Paula; Hernando, Carlos; Muriach, Maria MDPI (2021-10-02)In recent years, increasing numbers of women have participated in extremely long races. In adult males, there is a clear association between physiological levels of endogenous sex hormones and physical performance. ... -
Intracellular calcium chelation with BAPTA-AM modulates ethanol-induced behavioral effects in mice
Baliño, Pablo; Monferrer Sales, Lidón; Pastor Medall, Raúl; González Aragón, Carlos Manuel Elsevier (2012)Calcium (Ca2+) has been characterized as one of the most ubiquitous, universal and versatile intracellular signaling molecules responsible for controlling numerous cellular processes. Ethanol-induced effects on Ca2+ ... -
Involvement of ascorbate peroxidase and heat shock proteins on citrus tolerance to combined conditions of drought and high temperatures
Balfagón Sanmartín, Damián; I Zandalinas, Sara; Baliño, Pablo; Muriach, Maria; Gomez-Cadenas, Aurelio Elsevier (2018)Usually several environmental stresses occur in nature simultaneously causing a unique plant response. However, most of the studies until now have focused in individually-applied abiotic stress conditions. Carrizo citrange ... -
Is There A Role for Abscisic Acid, A Proven Anti-Inflammatory Agent, in the Treatment of Ischemic Retinopathies?
Baliño, Pablo; Gomez-Cadenas, Aurelio; López Malo, Daniel; Romero, Francisco J.; Muriach, Maria MDPI (2019)Ischemic retinopathies (IRs) are the main cause of severe visual impairment and sight loss, and are characterized by loss of blood vessels, accompanied by hypoxia, and neovascularization. Actual therapies, based on ... -
Modulation of ethanol-induced conditioned place preference in mice by 3-amino-1,2,4-triazole and D-penicillamine depends on ethanol dose and number of conditioning trials
Ledesma Llorente, Juan Carlos; Font Hurtado, Laura; Baliño, Pablo; González Aragón, Carlos Manuel Springer (2013)Previous studies have shown that both 3-amino-1,2,4-triazole (AT), which inhibits metabolism of ethanol (EtOH) to acetaldehyde by inhibiting catalase, and D-penicillamine (D-P), an acetaldehyde-sequestering agent, modulate ... -
Participation of L-type calcium channels in ethanol-induced behavioral stimulation and motor incoordination: Effects of diltiazem and verapamil
Baliño, Pablo; Pastor Medall, Raúl; González Aragón, Carlos Manuel Elsevier (2010-06)Calcium flux through voltage gate calcium channels (VGCC) is involved in many neuronal processes such as membrane depolarization, gene expression, hormone secretion, and neurotransmitter release. Several studies have shown ... -
Reduction in Central H2O2 Levels Prevents Voluntary Ethanol Intake in Mice: A Role for the Brain Catalase- H2O2 System in Alcohol Binge Drinking
Ledesma Llorente, Juan Carlos; Baliño, Pablo; González Aragón, Carlos Manuel Wiley (2014-01)Background: Hydrogen peroxide (H2O2) is the cosubstrate used by the enzyme catalase to form Compound I (the catalase-H2O2 system), which is the major pathway for the conversion of ethanol (EtOH) into acetaldehyde in the ... -
Role of CA2+/calmodulin on ethanol neurobehavioral effects
González Aragón, Carlos Manuel; Ledesma Llorente, Juan Carlos; Baliño, Pablo Springer (2014-05)Rationale. The cAMP-dependent protein kinase A (PKA) signaling transduction pathway has been shown to play an important role in the modulation of several ethanol-induced behaviors. Different studies have demonstrated ... -
Role of phosphodiesterase-4 on ethanol elicited locomotion and narcosis
Baliño, Pablo; Ledesma Llorente, Juan Carlos; González Aragón, Carlos Manuel Elsevier (2016)The cAMP signaling pathway has emerged as an important modulator of the pharmacological effects of ethanol. In this respect, the cAMP-dependent protein kinase has been shown to play an important role in the modulation of ...