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Gender and eye colour prediction discrepancies: A reply to criticisms (letter)
Martinez-Cadenas, Conrado; Peña Chilet, María; Llorca-Cardeñosa, Marta J.; Cervera, Raimundo; Ibarrola-Villava, Maider; Ribas, Gloria Elsevier (2014)Letter to the editor: In a letter published in this same issue, Liu et al. reply to a recently published article by us contesting the main conclusion of our original paper, namely, that gender is a factor that contributes to ... -
Gender is a major factor explaining discrepancies in eye colour prediction based on HERC2/OCA2 genotype and the IrisPlex model
Martinez-Cadenas, Conrado; Peña Chilet, María; Ibarrola-Villava, Maider; Ribas, Gloria Elsevier (2013)In recent years, several studies have greatly increased our understanding of the genetic basis underlying human eye colour variation. A large percentage of the eye colour diversity present in humans can already be genetically ... -
Genetic variants in PARP1 (rs3219090) and IRF4 (rs12203592) genes associated with melanoma susceptibility in a Spanish population
Peña Chilet, María; Blanquer Maceiras, Maite; Ibarrola-Villava, Maider; Martinez-Cadenas, Conrado; Martín González, Manuel; Gómez Fernández, Cristina; Mayor, Matías; Avilés, Juan Antonio; Lluch , Ana; Ribas, Gloria BioMed Central (2013-03)Background Few high penetrance genes are known in Malignant Melanoma (MM), however, the involvement of low-penetrance genes such as MC1R, OCA2, ASIP, SLC45A2 and TYR has been observed. Lately, genome-wide association ... -
Involvement of ANXA5 and ILKAP in Susceptibility to Malignant Melanoma
Santos, Alonso; Ribas, Gloria; Ibarrola-Villava, Maider; Peña Chilet, María; Martinez-Cadenas, Conrado; Gardeazabal, Jesús; Careaga, Jesús María; Pérez-Yarza, Gorka; Sánchez-Díez, Ana; Ratón-Nieto, Juan Antonio; Arroyo-Berdgo, Yoana; Carretero, Gregorio; Martín González, Manuel; Gómez Fernández, Cristina; Nagore, Eduardo; Asumendi, Aintzane; Boyano, Dolores Public Library of Science (2014)Single nucleotide-polymorphisms (SNPs) are a source of diversity among human population, which may be responsible for the different individual susceptibility to diseases and/or response to drugs, among other phenotypic ... -
Long telomere length and a TERT-CLPTM1 locus polymorphism association with melanoma risk
Llorca-Cardeñosa, Marta J.; Peña Chilet, María; Mayor, Matías; Gómez Fernández, Cristina; Casado, Beatriz; Martín González, Manuel; Carretero, Gregorio; Lluch , Ana; Martinez-Cadenas, Conrado; Ibarrola-Villava, Maider; Ribas, Gloria Elsevier (2014)Telomere length has been associated with the development of cancer. Studies have shown that shorter telomere length may be related to a decreased risk of cutaneous melanoma. Furthermore, deregulation of the telomere-maintaining ... -
Sex and MC1R variants in human pigmentation: Differences in tanning ability and sensitivity to sunlight between sexes
Hernando, Barbara; Ibarrola-Villava, Maider; Peña Chilet, María; Alonso, Santos; Ribas, Gloria; Martinez-Cadenas, Conrado Elsevier (2016) -
Sex-specific genetic effects associated with pigmentation, sensitivity to sunlight, and melanoma in a population of Spanish origin
Hernando, Barbara; Ibarrola-Villava, Maider; Fernández, Lara P.; Peña Chilet, María; Llorca-Cardeñosa, Marta J.; Oltra, Sara S.; Alonso, Santos; Boyano, Dolores; Martinez-Cadenas, Conrado; Ribas, Gloria BioMed Central (2016-03)Background Human pigmentation is a polygenic quantitative trait with high heritability. In addition to genetic factors, it has been shown that pigmentation can be modulated by oestrogens and androgens via up- or ...