• openAccess   Changes in drug use in European cities during early COVID-19 lockdowns ? A snapshot from wastewater analysis 

      Been, Frederic; Emke, Erik; Matias, Joao Luis; Baz Lomba, Jose Antonio; Boogaerts, Tim; Castiglioni, Sara; Campos-Mañas, Marina Celia; Celma, Alberto; Covaci, Adrian; de Voogt, Pim; Hernandez, Felix; Kasprzyk-Hordern, Barbara; ter Laak, Thomas; Reid, Malcolm; Salgueiro-González, Noelia; Steenbeek, Ruud; van Nuijs, Alexander; Zuccato, Ettore; Bijlsma, Lubertus Elsevier (2021-03-26)
      The COVID-19 outbreak has forced countries to introduce severe restrictive measures to contain its spread. In particular, physical distancing and restriction of movement have had important consequences on human behaviour ...
    • openAccess   Comparison of pharmaceutical, illicit drug, alcohol, nicotine and caffeine levels in wastewater with sale, seizure and consumption data for 8 European cities 

      Baz Lomba, Jose Antonio; Salvatore, Stefania; GRACIA LOR, EMMA; Bade, Richard; Castiglioni, Sara; Castrignanò, Erika; Causanilles, Ana; Hernandez, Felix; Kasprzyk-Hordern, Barbara; Kinyua, Juliet; McCall, Ann-Kathrin; van Nuijs, Alexander; Ort, Christoph; Plosz, Benedek; Ramin, Pedram; Reid, Malcolm; Rousis, Nikolaos I; Ryu, Yeonsuk; de Voogt, Pim; Bramness, Jorgen; Thomas, Kevin V. BioMed Central (2016)
      Background: Monitoring the scale of pharmaceuticals, illicit and licit drugs consumption is important to assess the needs of law enforcement and public health, and provides more information about the different trends within ...
    • closedAccess   Comparison of phosphodiesterase type V inhibitors use in eight European cities through analysis of urban wastewater 

      Causanilles, Ana; Rojas Cantillano, Daniela; Emke, Erik; Bade, Richard; Baz Lomba, Jose Antonio; Castiglioni, Sara; Castrignanò, Erika; GRACIA LOR, EMMA; Hernandez, Felix; Kasprzyk-Hordern, Barbara; Kinyua, Juliet; McCall, Ann Kathrin; van Nuijs, Alexander; Plosz, Benedek; Ramin, Pedram; Rousis, Nikolaos I; Ryu, Yeonsuk; Thomas, Kevin; de Voogt, Pim Elsevier (2018-06)
      In this work a step forward in investigating the use of prescription drugs, namely erectile dysfunction products, at European level was taken by applying the wastewater-based epidemiology approach. 24-h composite samples ...
    • openAccess   Drug use by music festival attendees: A novel triangulation approach using self-reported data and test results of oral fluid and pooled urine samples 

      Gjerde, Hallvard; Gjersing, Linn; Baz Lomba, Jose Antonio; Bijlsma, Lubertus; Salgueiro-González, Noelia; Furuhaugen, Havard; Bretteville-Jensen, Anne LIne; Hernandez, Felix; Castiglioni, Sara; Amundsen, Ellen Johanna; Zuccato, Ettore Taylor & Francis (2019)
      Background: Self-reported data are commonly used when investigating illicit substance use. However, self-reports have well-known limitations such as limited recall and socially desirable responding. Mislabeling or ...
    • closedAccess   Enantiomeric profiling of chiral illicit drugs in a pan-European study 

      Castrignanò, Erika; Yang, Zhugen; Bade, Richard; Baz Lomba, Jose Antonio; Castiglioni, Sara; Causanilles, Ana; Covaci, Adrian; GRACIA LOR, EMMA; Hernandez, Felix; Kinyua, Juliet; McCall, Ann Kathrin; van Nuijs, Alexander; Ort, Christoph; Plosz, Benedek; Ramin, Pedram; Rousis, Nikolaos I; Ryu, Yeonsuk; Thomas, Kevin V.; de Voogt, Pim; Zuccato, Ettore; Kasprzyk-Hordern, Barbara Elsevier (2018)
      The aim of this paper is to present the first study on spatial and temporal variation in the enantiomeric profile of chiral drugs in eight European cities. Wastewater-based epidemiology (WBE) and enantioselective analysis ...
    • openAccess   Estimation of caffeine intake from analysis of caffeine metabolites in wastewater 

      GRACIA LOR, EMMA; Rousis, Nikolaos I; Zuccato, Ettore; Bade, Richard; Baz Lomba, Jose Antonio; Castrignanò, Erika; Causanilles, Ana; Hernandez, Felix; Kasprzyk-Hordern, Barbara; Kinyua, Juliet; McCall, Ann-Kathrin; van Nuijs, Alexander; Plosz, Benedek; Ramin, Pedram; Ryu, Yeonsuk; Santos, Miguel M.; Thomas, Kevin V.; de Voogt, Pim; Yang, Zhugen; Castiglioni, Sara Elsevier (2017-12)
      Caffeine metabolites in wastewater were investigated as potential biomarkers for assessing caffeine intake in a population. The main human urinary metabolites of caffeine were measured in the urban wastewater of ten European ...
    • closedAccess   Improving wastewater-based epidemiology to estimate cannabis use: focus on the initial aspects of the analytical procedure 

      Causanilles, Ana; Baz Lomba, Jose Antonio; Burgard, Daniel A.; Emke, Erik; González-Mariño, Iria; Krizman-Matasic, Ivona; Li, Angela; Love, Arndis S. C.; McCall, Ann Kathrin; Montes, Rosa; van Nuijs, Alexander; Ort, Christoph; Quintana, José B.; Senta, Ivan; Terzic, Senka; Hernandez, Felix; de Voogt, Pim; Bijlsma, Lubertus Elsevier (2017-10-02)
      estimating drug use by the general population, based on the quantitative analysis of specific human metabolites of illicit drugs in urban wastewater. Cannabis is the most commonly used illicit drug and of high interest for ...
    • openAccess   Increased levels of the oxidative stress biomarker 8-iso-prostaglandin F2α in wastewater associated with tobacco use 

      Ryu, Yeonsuk; GRACIA LOR, EMMA; Bade, Richard; Baz Lomba, Jose Antonio; Bramness, Jorgen; Castiglioni, Sara; Castrignanò, Erika; Causanilles, Ana; Covaci, Adrian; de Voogt, Pim; Hernandez, Felix; Kasprzyk-Hordern, Barbara; Kinyua, Juliet; McCall, Ann-Kathrin; Ort, Christoph; Plosz, Benedek; Ramin, Pedram; Rousis, Nikolaos I; Reid, Malcolm; Thomas, Kevin V. Nature Publishing Group (2016)
      Wastewater analysis has been demonstrated to be a complementary approach for assessing the overall patterns of drug use by a population while the full potential of wastewater-based epidemiology has yet to be explored. ...
    • closedAccess   Influent wastewater analysis to investigate emerging trends of new psychoactive substances use in Europe 

      Salgueiro-González, Noelia; Been, Frederic; Bijlsma, Lubertus; Boogaerts, Tim; Covaci, Adrian; Baz Lomba, Jose Antonio; Kasprzyk-Hordern, Barbara; Matias, João; Ort, Christoph; Bodík, Igor; Heath, Ester; Styszko, Katarzyna; Emke, Erik; Hernandez, Felix; van Nuijs, Alexander; Castiglioni, Sara Elsevier (2024-01-27)
      Wastewater-based epidemiology (WBE) can provide objective and timely information on the use of new psychoactive substances (NPS), originally designed as legal alternatives of internationally controlled drugs. NPS have ...
    • closedAccess   International snapshot of new psychoactive substance use: Case study of eight countries over the 2019/2020 new year period 

      Bade, Richard; White, Jason M.; Chen, Jingjing; Baz Lomba, Jose Antonio; Been, Frederic; Bijlsma, Lubertus; Universitat Jaume I. Departament de Química Física i Analítica; Burgard, Daniel A.; Castiglioni, Sara; Salgueiro-González, Noelia; Celma, Alberto; Universitat Jaume I. Departament de Química Física i Analítica; Chappell, Andrew; Emke, Erik; Steenbeek, Ruud; Wang, Degao; Zuccato, Ettore; Gerber, Cobus Elsevier (2021-02-03)
      There is considerable concern around the use of new psychoactive substances (NPS), but still little is known about how much they are really consumed. Analysis by forensics laboratories of seized drugs and post-mortem samples ...
    • openAccess   Liquid chromatography-tandem mass spectrometry determination of synthetic cathinones and phenethylamines in influent wastewater of eight European cities 

      Bade, Richard; Bijlsma, Lubertus; Sancho, Juan V; Baz Lomba, Jose Antonio; Castiglioni, Sara; Castrignanò, Erika; Causanilles, Ana; GRACIA LOR, EMMA; Kasprzyk-Hordern, Barbara; Kinyua, Juliet; McCall, Ann-Kathrin; van Nuijs, Alexander; Ort, Christoph; Plosz, Benedek; Ramin, Pedram; Rousis, Nikolaos I; Ryu, Yeonsuk; Thomas, Kevin V.; de Voogt, Pim; Zuccato, Ettore; Hernandez, Felix Elsevier (2017-02)
      The popularity of new psychoactive substances (NPS) has grown in recent years, with certain NPS commonly and preferentially consumed even following the introduction of preventative legislation. With the objective to improve ...
    • openAccess   Liquid chromatography-tandem mass spectrometry determination of synthetic cathinones and phenethylamines in influent wastewater of eight European cities 

      Bade, Richard; Bijlsma, Lubertus; Sancho, Juan V; Baz Lomba, Jose Antonio; Castiglioni, Sara; Castrignanò, Erika; Causanilles, Ana; GRACIA LOR, EMMA; Kasprzyk-Hordern, Barbara; Kinyua, Juliet; McCall, Ann-Kathrin; van Nuijs, Alexander; Ort, Christoph; Plosz, Benedek; Ramin, Pedram; Rousis, Nikolaos I; Ryu, Yeonsuk; Thomas, Kevin V.; de Voogt, Pim; Zuccato, Ettore; Hernandez, Felix Elsevier (2017)
      The popularity of new psychoactive substances (NPS) has grown in recent years, with certain NPS commonly and preferentially consumed even following the introduction of preventative legislation. With the objective to improve ...
    • openAccess   Monitoring psychoactive substance use at six European festivals through wastewater and pooled urine analysis 

      Bijlsma, Lubertus; Celma, Alberto; Castiglioni, Sara; Salgueiro-González, Noelia; Bou Iserte, Lledó; Baz Lomba, Jose Antonio; Reid, Malcolm; Dias, M.J.; Lopes, Alvaro; Matias, Joao Luis; Pastor Alcañiz, Laura; Radonic, J.; Turk Sekulic, M.; Shine, Trevor; van Nuijs, Alexander; Hernandez, Felix; Zuccato, Ettore Elsevier (2020-07-10)
      The consumption of psychoactive substances is considered a growing problem in many communities. Moreover, new psychoactive substances (NPS) designed as (legal) substitutes to traditional illicit drugs are relatively easily ...
    • openAccess   Multi-year interlaboratory exercises for the analysis of illicit drugs and metabolites in wastewater: development of a quality control system 

      van Nuijs, Alexander; Lai, Foon Yin; Been, Frederic; Andrés-Costa, Maria Jesús; Barron, León P.; Baz Lomba, Jose Antonio; Berset, Jean-Daniel; Benaglia, Lisa; Bijlsma, Lubertus; Burgard, Daniel A.; Castiglioni, Sara; Christophoridis, Christophoros; Covaci, Adrian; de Voogt, Pim; Emke, Erik; Fatta-Kassinos, Despo; Fick, Jerker; Hernandez, Felix; Gerber, Cobus; González-Marino, Iria; Grabic, Roman; Gunnar, Teemu; Kannan, Kurunthachalam; Karolak, Sara; Kasprzyk-Hordern, Barbara; Kokot, Zenon; Krizman-Matasic, Ivona; Li, Angela; Li, Xiqing; Love, Arndis S. C.; López de Alda, Miren; McCall, Ann Kathrin; Meyer, Markus R.; Oberacher, Herbert; O'Brien, Jake; Quintana, José B.; Reid, Malcolm; Schneider, Serge; Sadler Simoes, Susana; Thomaidis, Nikolaos; Thomas, Kevin; Yargeau, Viviane; Ort, Christoph Elsevier (2018)
      This study presents the development of a worldwide inter-laboratory testing scheme for the analysis of seven illicit drug residues in different matrices (standard solutions, tap- and wastewater). By repeating this exercise ...
    • openAccess   Spatio‐temporal assessment of illicit drug use at large scale: evidence from 7 years of international wastewater monitoring 

      González-Mariño, Iria; Baz Lomba, Jose Antonio; Alygizakis, Nikiforos; Andrés-Costa, Maria Jesús; Bade, Richard; Bannwarth, Anne; Barron, Leon; Been, Frederic; Benaglia, Lisa; Berset, Jean-Daniel; Bijlsma, Lubertus; Bodík, Igor; Brenner, Asher; Brock, Andreas L.; Burgard, Daniel A.; Castrignanò, Erika; Celma, Alberto; Christophoridis, Christophoros; Covaci, Adrian; Delémont, Olivier; de Voogt, Pim; Devault, Damien A.; Mário J. Dias, Mário J.; Emke, Erik; Esseiva, Pierre; Fatta-Kassinos, Despo; Fedorova, Ganna; Fytianos, Konstantinos; Gerber, Cobus; Grabic, Roman; GRACIA LOR, EMMA; Grüner, Stefan; Gunnar, Teemu; Hapeshi, Evroula; Heath, Ester; Helm, Björn; Hernandez, Felix; Kankaanpaa, Aino; Kasprzyk-Hordern, Barbara; Krizman-Matasic, Ivona; Lai, Foon Yin; Lechowicz, Wojciech; Lopes, Alvaro; López de Alda, Miren; López-García, Ester; Löve, Arndís; Mastroianni, Nicola; McEneff, Gillian; Montes, Rosa; Munro, Kelly; Nefau, Thomas; Oberacher, Herbert; O'Brien, Jake William; Oertel, Reinhard; Olafsdottir, Kristin; Picó, Yolanda; Plosz, Benedek; Polesel, Fabio; Postigo, Cristina; Quintana, José Benito; Ramin Pedram; Reid, Malcolm J.; Rice, Jack; Rodil, Rosario; Salgueiro-González, Noelia; Schubert, Sara; Senta, Ivan; Simões, Susana M.; Sremački, Maja; Styszko, Katarzyna; Terzic, Senka; Thomaidis, Nikolaos; Thomas, Kevin V.; Tscharke, Ben J.; Udrisard, Robin; van Nuijs, Alexander; Yargeau Viviane; Zuccato, Ettore; Castiglioni, Sara; Ort, Christoph Wiley (2020-01)
      Background and aims: Wastewater‐based epidemiology is an additional indicator of drug use that is gaining reliability to complement the current established panel of indicators. The aims of this study were to: (i) assess ...
    • closedAccess   Wastewater-based epidemiology to assess pan-European pesticide exposure 

      Rousis, Nikolaos I; GRACIA LOR, EMMA; Zuccato, Ettore; Bade, Richard; Baz Lomba, Jose Antonio; Castrignanò, Erika; Causanilles, Ana; Covaci, Adrian; de Voogt, Pim; Hernandez, Felix; Kasprzyk-Hordern, Barbara; Kinyua, Juliet; McCall, Ann-Kathrin; Plosz, Benedek; Ramin, Pedram; Ryu, Yeonsuk; Thomas, Kevin; van Nuijs, Alexander; Yang, Zhugen; Castiglioni, Sara Elsevier (2017)
      Human biomonitoring, i.e. the determination of chemicals and/or their metabolites in human specimens, is the most common and potent tool for assessing human exposure to pesticides, but it suffers from limitations such as ...