Listar por autoría "19086f55-d62d-4762-9716-963245baec9a"
Mostrando ítems 1-20 de 27
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A Dual Stimuli Responsive Supramolecular Gel Provides Insulin Hydrolysis Protection and Redox-Controlled Release of Actives
Navarro Barreda, Diego; Angulo-Pachón, César A.; Bedrina, Begoña; Galindo, Francisco; Miravet, Juan Wiley (2020)Two supramolecular hydrogelators containing a central disulfide moiety and terminal carboxylic acid groups are studied. On the one hand, the hydrogels are responsive to a reductive environment, which transforms the disulfide ... -
Adsorption of Rose Bengal on a self-assembled fibrillar network affords a thermally switchable oxygenation photocatalyst and a thermochromic soft material
Arnau del Valle, Carla; Felip-León, Carles; Angulo-Pachón, César A.; Galindo, Francisco; Miravet, Juan Elsevier (2019-10-03)Rose Bengal (RB) can be homogeneously dispersed in dichloromethane by its adsorption on the fibrillar network of a molecular gel formed in this solvent. The RB loaded gel was visualized by confocal scanning laser microscopy, ... -
Alkaline cations dramatically control molecular hydrogelation by an amino acid-derived anionic amphiphile
Angulo-Pachón, César A.; Pozo, Víctor; Miravet, Juan Elsevier (2023-01-03)Understanding the factors that control the formation of (supra)molecular hydrogels permits a rational tuning of their properties and represents a primary challenge for developing smart biocompatible soft materials. Hydrogel ... -
Antiplasmodial and Cytotoxic Activity of Piper Piedecuestanum Trel. and Yunck
Mesa Vanegas, Ana Maria; Toro Suaza, Jhon Fredy; Vásquez Cardona, Ana María; Blair Trujillo, Silvia; Peláez Jaramillo, Carlos; Diaz-Oltra, Santiago; Angulo-Pachón, César A.; Carda, Miguel Academic Journals, New York (2018)ackground and Objective: Plasmodium resistance to antimalarial drugs has expanded and in tensified, making new and effective antimalarial drugs urgently. The objective of this work was the in vitro evaluation of ... -
Deamidation of pseudopeptidic molecular hydrogelators and its application to controlled release
Angulo-Pachón, César A.; Navarro Barreda, Diego; Rueda, Celia M.; Galindo, Francisco; Miravet, Juan Elsevier (2017-07)Hypothesis The incorporation of a succinic acid-derived moiety in amino acid derivatives would favor an intramolecular catalysis of a deamidation reaction. Such reaction would permit controlled disassembly of molecular ... -
High Optical Performance of Cyan‐Emissive CsPbBr3 Perovskite Quantum Dots Embedded in Molecular Organogels
Vallés Pelarda, Marta; Gualdrón Reyes, Andrés Fabián; Felip-León, Carles; Angulo-Pachón, César A.; Agouram, Said; Muñoz-Sanjosé, Vicente; Miravet, Juan; Galindo, Francisco; Mora-Sero, Ivan Wiley (2021)Perovskite quantum dots (PQDs) have fascinating optoelectronic properties, such as high photoluminescence quantum yield (PLQY) for a broad range of materials, and the possibility to obtain different bandgaps with the same ... -
Improvement of molecular gel formation efficiency by adjusting preorganization of amino acid-derived flexible molecules. A NMR and thermodynamic study
Angulo-Pachón, César A.; Gascó-Catalán, Carolina; Ojeda, Juan José; Miravet, Juan Wiley (2016)The efficiency of the formation of molecular gels of simple de-rivatives of l-valineand l-isoleucine is greatl yimproved in dif-ferent organic solvents when ahexyl fragment is replaced byabulkier cyclohexyl one. Astudy ... -
In between molecules and self-assembled fibrillar networks: Highly stable nanogel particles from a low molecular weight hydrogelator
Torres Martínez, Ana; Angulo-Pachón, César A.; Galindo, Francisco; Miravet, Juan Royal Society of Chemistry (2019-03-25)The preparation of molecular, non-polymeric, nanogels from a low molecular weight hydrogelator is reported. Molecular nanogels are expected to overcome issues associated with the use of polymeric nanogels in biomedicine ... -
In situ synthesis-gelation at room temperature vs. heating–cooling procedure. Fine tuning of molecular gels derived from succinic acid and L-valine
Fontanillo, Miriam; Angulo-Pachón, César A.; Escuder, Beatriu; Miravet, Juan Elsevier (2013-12)Hypothesis The reaction between succinic anhydride and a diamine derived from L-valine should afford efficiently a molecular gelator. Based on this reaction, it should be feasible to prepare molecular gels at room ... -
Liposome-Enveloped Molecular Nanogels
Torres-Martínez, Ana; Angulo-Pachón, César A.; Galindo, Francisco; Miravet, Juan American Chemical Society (2019)Novel hydrogel@liposome particles were prepared by pHtriggered molecular gel formation inside of liposomes loaded with a lowmolecular weight gelator derived from L-valine (1). Liposome formation was carried out using ... -
Mechanistic Insight into the Lability of the Benzyloxycarbonyl (Z) Group inN-Protected Peptides under Mild Basic Conditions
Tena Solsona, Marta; Angulo-Pachón, César A.; Escuder, Beatriu; Miravet, Juan Wiley Online Library (2014)The unexpected lability of Z protecting group under mild basic conditions at room temperature is explained by a mechanism based on anchimeric assistance. It is found that the vicinal amide group stabilizes the tetrahedral ... -
Non-Polymeric Nanogels as Versatile Nanocarriers: Intracellular Transport of the Photosensitizers Rose Bengal and Hypericin for Photodynamic Therapy
Torres-Martínez, Ana; Bedrina, Begoña; Falomir, Eva; Marín, María J.; Angulo-Pachón, César A.; Galindo, Francisco; Miravet, Juan American Chemical Society (2021-04-19)The use of nanocarriers for intracellular transport of actives has been extensively studied in recent years and represents a central area of nanomedicine. The main novelty of this paper lies on the use of nanogels formed ... -
Photoactive Hexanuclear Molybdenum Nanoclusters Embedded in Molecular Organogels
Arnau del Valle, Carla; Felip-León, Carles; Angulo-Pachón, César A.; Mikhailov, Maxim; Sokolov, Maxim; Miravet, Juan; Galindo, Francisco American Chemical Society (2019-07-05)Hexanuclear molybdenum clusters are attractive species because of their outstanding photonic properties, and in the past they have been attached to a variety of supports such as organic polymers and inorganic nanoparticles, ... -
Photobehavior of the antipsychotic drug cyamemazine in a supramolecular gel protective environment
Vendrell Criado, Victoria; Angulo-Pachón, César A.; Miravet, Juan; Galindo, Francisco; Miranda, Miguel A.; Jiménez, M. Consuelo Elsevier (2019-11-06)In this work, a molecular hydrogel made of gelator (S)-4-((3-methyl-1-(nonylamino)-1-oxobutan-2-yl)amino)-4-oxobutanoic acid (SVN) has been employed as soft container to modify the photochemical and photophysical behavior ... -
Photoreversible formation of nanotubes in water from an amphiphilic azobenzene derivative
Navarro Barreda, Diego; Angulo-Pachón, César A.; Galindo, Francisco; Miravet, Juan The Royal Society of Chemistry (2021-10-13)An anionic azobenzene-appended derivative of L-ValylGlycine self-assembles into nanotubes in water. Irradiation with 365 nm light provokes trans–cis isomerization of the azobenzene unit and subsequent tube disassembly. ... -
Rational design of a supramolecular gel based on a Zn(II)–salophen bis-dipeptide derivative
Piccino, Martina; Angulo-Pachón, César A.; Ballester, Pablo; Escuder, Beatriu; Cort, Antonella Dalla Royal Society of Chemistry (2016)We report the rational design and synthesis of a supramolecular gelator based on a Zn(II)–salophen derivative functionalized with L-valine residues. This compound is able to gelate acetonitrile by self-assembly into helical ... -
Reduction-triggered Disassembly of Organic Cationic Nanorods Produces a Cysteine Protease Mimic (Miravet et al.)
Navarro Barreda, Diego; Angulo-Pachón, César A.; Galindo, Francisco; Miravet, Juan Wiley (2023)The emergence of catalytic activity associated with a disassembly process is reported, reminiscent of complex biological systems. A cystine derivative with pendant imidazole groups self-assembles into cationic nanorods ... -
Self-Assembly Controls Reactivity with Nitric Oxide: Implications for Fluorescence Sensing
Felip-León, Carles; Angulo-Pachón, César A.; Miravet, Juan; Galindo, Francisco American Chemical Society (2018)Three molecules containing the fluorophore 4-amino-1,8-naphthalimide (ANI) and showing different tendencies to self-assembly in aqueous environment have been prepared and fully characterized. The fluorescence emissions of ... -
Self‐Assembled Nanofibrilar Networks: Boosting Hydrogelation Efficiency by Replacement of a Pyridine Moiety by a Quinoline One
Angulo-Pachón, César A.; Diaz-Oltra, Santiago; Ojeda, Juan José; Falomir, Eva; Galindo, Francisco; Miravet, Juan Wiley (2015-08)A new molecular hydrogelator consisting of a L‐Valine derivative with appended quinoline units behaves as a supramolecular superhydrogelator forming gels at such low concentrations as 0.8 mM (0.05% w/w). On the other hand, ... -
Stereoselective Synthesis of the Cytotoxic 14-Membered Macrolide Aspergillide A
Diaz-Oltra, Santiago; Angulo-Pachón, César A.; Murga, Juan; Carda, Miguel; Marco, J. Alberto American Chemical Society (2010)A stereoselective synthesis of the cytotoxic 14-membered macrolide aspergillide A has been performed. The preparation of a cis-2,6-disubstituted tetrahydropyran ring via stereoselective reduction of an intermediate cyclic ...