• openAccess   Arsenic exposure and respiratory outcomes during childhood in the INMA study 

      Signes-Pastor, Antonio Jose; Díaz-Coto, Susana; Martinez Camblor, Pablo; Carey, Manus; Soler-Blasco, Raquel; García Villarino, Miguel; Fernández Somoano, Ana; Julvez, Jordi; Carrasco, Paula; LERTXUNDI MANTEROLA, AITANA; SANTA MARINA, LORETO; Casas, Maribel; meharg, andy; Karagas, Margaret R; Vioque, Jesus PLoS (2022-09-09)
      Ingested inorganic arsenic (iAs) is a human carcinogen that is also linked to other adverse health effects, such as respiratory outcomes. Yet, among populations consuming low-arsenic drinking water, the impact of iAs ...
    • openAccess   Association between the Use of Folic Acid Supplements during Pregnancy and Children's Cognitive Function at 7-9 Years of Age in the INMA Cohort Study 

      Compañ Gabucio, Laura M; Torres-Collado, Laura; Garcia de la Hera, Manuela; Fernández Somoano, Ana; Tardon, Adonina; Julvez, Jordi; Sunyer Deu, Jordi; Rebagliato, Marisa; Murcia, Mario; Ibarluzea, Jesus; SANTA MARINA, LORETO; Vioque, Jesus MDPI (2022-09-25)
      This study investigated the association between maternal low (<400 μg/day) or high (≥1000 μg/day) folic acid supplements (FAs) use during pregnancy and the attentional function and working memory in boys and girls at age ...
    • closedAccess   Cohort Profile: Design and methods of the PREDIMED-Plus randomized trial 

      Martínez González, Miguel Ángel; Buil-Cosiales, Pilar; Corella, Dolores; Bulló, Mònica; Fitó, Montserrat; Vioque, Jesus; Romaguera, Dora; Martínez, J. Alfredo; Wärnberg, Julia; López Miranda, José; Estruch, Ramon; Bueno Cavanillas, Aurora; Arós, Fernando; Tur, Josep; Tinahones Madueño, Francisco José; Serra-Majem, Lluis; Martín, Vicente; Lapetra, José; Vázquez, Clotilde; Pintó, Xavier; Vidal, Josep; Daimiel-Ruiz, Lidia Ángeles; Delgado Rodríguez, Miguel; Matía, Pilar; Ros, Emilio; Fernández Aranda, Fernando; Botella, Cristina; Puy Portillo-Baquedano, María; Lamuela Raventós, Rosa María; Marcos, Ascensión; Sáez, Guillermo; Gómez-Gracia, Enrique; Ruiz-Canela, Miguel; Toledo, Estefanía; Alvarez-Alvarez, Ismael; Díez Espino, Javier; Sorlí, José V; Basora, Josep; Castañer, Olga; Schröder, Helmut; Navarrete-Muñoz, Eva María; Zulet, M. Angeles; García-Rios, Antonio; Salas-Salvadó, Jordi Oxford University Press (2019-04)
      The PREDIMED (in Spanish: PREvención con DIeta MEDiterránea) primary prevention trial1–3 reported in 2013 that long-term adherence to an energy-unrestricted Mediterranean diet (MedDiet), supplemented with either extra-virgin ...
    • closedAccess   Comparison of urinary iodine levels in women of childbearing age during and after pregnancy 

      Castilla, Ane M.; Murcia, Mario; Arrizabalaga, Juan José; Espada, Mercedes; Julvez, Jordi; Basterretxea, Mikel; Álvarez Pedrerol, Mar; Estarlich, Marisa; Moreno, Elena; Guxens, Mònica; Vioque, Jesus; Rebagliato, Marisa Springer (2018-08)
      Purpose Median urinary iodine concentration (UIC) is used to describe the iodine status of a population. However, the link between UIC and iodine intake may vary during pregnancy. The aim of this study was to compare ...
    • openAccess   Dietary intake in pregnant women in a Spanish Mediterranean area: as good as it is supposed to be? 

      Rebagliato, Marisa; Ramón, Rosa; Murcia, Mario; Navarrete-Muñoz, Eva María; Vioque, Jesus; Ballester, Ferran; Rodríguez-Bernal, Clara L.; Quiles, Joan Cambridge University Press (2013-08)
      Objective To assess food and nutrient intakes and compliance with nutritional recommendations in pregnant women according to selected sociodemographic characteristics. Design Cross-sectional study based on data from the ...
    • closedAccess   Exposure to mercury among Spanish preschool children: Trend from birth to age four 

      Llop, Sabrina; Murcia, Mario; Aguinagalde, Xabier; Vioque, Jesus; Rebagliato, Marisa; Cases, Amparo; Iñiguez, Carmen; López Espinosa, María José; Amurrio, Ascensión; Navarrete-Muñoz, Eva María; Ballester, Ferran Elsevier (2014)
      The purpose of this study is to describe the total hair mercury concentrations and their determinants in preschool Spanish children, as well as to explore the trend in mercury exposure from birth to the age four. This ...
    • closedAccess   High doses of folic acid in the periconceptional period and risk of low weight for gestational age at birth in a population based cohort study. 

      Navarrete-Muñoz, Eva María; Valera-Gran, Desirée; Garcia de la Hera, Manuela; González-Palacios, Sandra; Riaño-Galan, Isolina; Murcia, Mario; Lertxundi, Aitana; Guxens, Mònica; Tardon, Adonina; Amiano, Pilar; Vrijheid, Martine; Rebagliato, Marisa; Vioque, Jesus Springer (2019)
      Purpose We investigated the association between maternal use of folic acid (FA) during pregnancy and child anthropometric measures at birth. Methods We included 2302 mother–child pairs from a population-based birth cohort ...
    • closedAccess   Maternal copper status and neuropsychological development in infants and preschool children 

      Amorós Salvador, Rubén; Murcia, Mario; González, Llúcia; Soler-Blasco, Raquel; Rebagliato, Marisa; Iñiguez, Carmen; Carrasco, Paula; Vioque, Jesus; Broberg, Karin; Levi, Michael; López Espinosa, María José; Ballester, Ferran; Llop, Sabrina Elsevier (2019-04)
      Introduction Copper (Cu) is an essential element involved in biological processes; however, excessive Cu could be harmful because of its reactive nature. Very few studies have evaluated its potential neurotoxic effects. ...
    • closedAccess   Maternal Thyroid Dysfunction during Gestation, Preterm Delivery, and Birthweight. The Infancia y Medio Ambiente Cohort, Spain 

      León, Gemma; Murcia, Mario; Rebagliato, Marisa; Álvarez Pedrerol, Mar; Castilla, Ane M.; Basterretxea, Mikel; Iñiguez, Carmen; Fernández Somoano, Ana; Blarduni, Elizabeth; Foradada, Carles M.; Tardon, Adonina; Vioque, Jesus Wiley (2015)
      Background: Maternal clinical thyroid disorders can cause reproductive complications. However, the effects ofmild thyroid dysfunctions are not yet well established. The aim was to evaluate the association of maternal ...
    • openAccess   Mediterranean, DASH, and MIND Dietary Patterns and Cognitive Function: The 2-Year Longitudinal Changes in an Older Spanish Cohort 

      Nishi, Stephanie; Babio, Nancy; Gomez-Martinez, Carlos; Martínez González, Miguel Ángel; Ros, Emilio; Corella, Dolores; Castaner, Olga; Martínez, J. Alfredo; Alonso-Gómez, Ángel M.; Waernberg, Julia; Vioque, Jesus; Romaguera, Dora; Lopez-Miranda, Jose; Estruch, Ramon; Tinahones, Francisco J; Lapetra, Jose; Serra-Majem, Lluis; Bueno Cavanillas, Aurora; Tur, Josep; Coltell, Oscar; Salas-Salvadó, Jordi Frontiers Media (2021)
      Background and Aims: Plant-forward dietary patterns have been associated with cardiometabolic health benefits, which, in turn, have been related to cognitive performance with inconsistent findings. The objective of this ...
    • openAccess   Postnatal exposure to mercury and neuropsychological development among preschooler children 

      Llop, Sabrina; Murcia, Mario; Amorós Salvador, Rubén; Julvez, Jordi; SANTA MARINA, LORETO; Soler-Blasco, Raquel; Rebagliato, Marisa; Iñiguez, Carmen; Aguinagalde, Xabier; Iriarte, Gorka; Lopez-Espinosa, Maria-Jose; Andiarena, Ainara; Gonzalez, Llúcia; Vioque, Jesus; Sunyer Deu, Jordi; Ballester, Ferran Springer (2020-03-13)
      The objective of this study was to describe the postnatal exposure to Hg and to evaluate its association with neuropsychological development among preschool children. The study population are 4–5 years old children (n = ...
    • openAccess   Pre and postnatal exposure to mercury and respiratory health in preschool children from the Spanish INMA Birth Cohort Study 

      Carrasco, Paula; Estarlich, Marisa; Iñiguez, Carmen; Ferrero, Amparo; Murcia, Mario; Esplugues Cebrián, Ana; Vioque, Jesus; SANTA MARINA, LORETO; Zabaleta, Carlos; Iriarte, Gorka; Fernández Somoano, Ana; Tardon, Adonina; Vrijheid, Martine; Sunyer Deu, Jordi; Ballester, Ferran; Llop, Sabrina Elsevier (2021)
      Effects of mercury on maturing immune system have been reported, however the association with respiratory and allergy problems during infancy remains unclear. The aim of this study is to evaluate the association between ...
    • closedAccess   Prenatal exposure to mercury and longitudinally assesssed fetal growth: Relation and effect modifiers 

      Ballester, Ferran; Íñiguez, Carmen; Murcia, Mario; Guxens, Mònica; Basterretxea, Mikel; Rebagliato, Marisa; Vioque, Jesus; Lertxundi, Aitana; Fernández Somoano, Ana; Tardon, Adonina; Sunyer Deu, Jordi; Llop, Sabrina Elsevier (2018-01)
      Background:Prenatal mercury exposure has been related to reductions in anthropometry at birth. Levels ofmercury have been reported as being relatively elevated in the Spanish population.Objective:To investigate the relation ...
    • closedAccess   Prenatal exposure to mercury and neuropsychological development in young children: the role of fish consumption 

      Llop, Sabrina; Ballester, Ferran; Murcia, Mario; Forns, Joan; Tardon, Adonina; Andiarena, Ainara; Vioque, Jesus; Ibarluzea, Jesus; Fernández Somoano, Ana; Sunyer Deu, Jordi; Julvez, Jordi; Rebagliato, Marisa; López Espinosa, María José Oxford University Press (2016-11)
      Background: Vulnerability of the central nervous system to mercury exposure is increased during early development. The aim of this study is to evaluate the association between prenatal exposure to mercury and child ...
    • closedAccess   Prenatal mercury exposure and birth outcomes 

      Murcia, Mario; Ballester, Ferran; Enning, Ashley Michel; Iñiguez, Carmen; Valvi, Damaskini; Basterretxea, Mikel; Rebagliato, Marisa; Vioque, Jesus; Maruri, Maite; Tardon, Adonina; Riaño, Isolina; Vrijheid, Martine; Llop, Sabrina Elsevier (2016-11)
      Background: Results regarding the association between mercury exposure and anthropometry at birth, gestational length and placental weight are inconsistent, as is the role of seafood intake in these asso- ciations. Objective: ...
    • openAccess   Reproducibility and validity of a food frequency questionnaire among pregnant women in a Mediterranean area 

      Vioque, Jesus; Navarrete-Muñoz, Eva María; Giménez Monzó, Daniel; Garcia de la Hera, Manuela; Granado, Fernando; Young, Ian S.; Ramón, Rosa; Ballester, Ferran; Murcia, Mario; Rebagliato, Marisa; Iñiguez, Carmen; INMA-Valencia Cohort Study BioMed Central (2013)
      Background: Studies exploring the role of diet during pregnancy are still scarce, in part due to the complexity of measuring diet and to the lack of valid instruments. The aim of this study was to examine the reproducibility ...
    • openAccess   Reproducibility and validity of a food frequency questionnaire designed to assess diet in children aged 4-5 years 

      Vioque, Jesus; Giménez Monzó, Daniel; Navarrete-Muñoz, Eva María; Garcia de la Hera, Manuela; González-Palacios, Sandra; Rebagliato, Marisa; Ballester, Ferran; Murcia, Mario; Iñiguez, Carmen; Granado, Fernando; INMA-Valencia Cohort Study Public Library of Science (2016)
      Background The food frequency questionnaire (FFQ) is the most efficient and cost-effective method to investigate the relationship between usual diet and disease in epidemiologic studies. Although FFQs have been validated ...
    • closedAccess   Synergism between exposure to mercury and use of iodine supplements on thyroid hormones in pregnant women 

      Llop, Sabrina; López Espinosa, María José; Murcia, Mario; Álvarez Pedrerol, Mar; Vioque, Jesus; Aguinagalde, Xabier; Julvez, Jordi; Aurrekoetxea, J. J.; Espada, Mercedes; SANTA MARINA, LORETO; Rebagliato, Marisa; Ballester, Ferran Elsevier (2015)
      To evaluate the association between mercury exposure and thyroid-stimulating hormone (TSH), total triiodothyronine (TT3) and free thyroxine (FT4) levels during pregnancy as well as to explore if there is any synergic action ...
    • openAccess   Taxonomic and Functional Fecal Microbiota Signatures Associated With Insulin Resistance in Non-Diabetic Subjects With Overweight/Obesity Within the Frame of the PREDIMED-Plus Study 

      Atzeni, Alessandro; Bastiaanssen, Thomaz; Cryan, John; Tinahones, Francisco J; Vioque, Jesus; Corella, Dolores; Fitó, Montserrat; Vidal, Josep; Moreno-Indias, Isabel; Gómez Pérez, Ana María; Torres-Collado, Laura; Coltell, Oscar; Castaner, Olga; Bulló, Mònica; Salas, Jordi Frontiers Media (2022)
      Objective: An altered gut microbiota has been associated with insulin resistance, a metabolic dysfunction consisting of cellular insulin signaling impairment. The aim of the present study is to determine the taxonomic and ...
    • openAccess   The use of lower or higher than recommended doses of folic acid supplements during pregnancy is associated with child attentional dysfunction at 4-5 years of age in the INMA Project 

      Compañ Gabucio, Laura M; Garcia de la Hera, Manuela; Torres-Collado, Laura; Fernández Somoano, Ana; Tardon, Adonina; Guxens, Mònica; Vrijheid, Martine; Rebagliato, Marisa; Murcia, Mario; Ibarluzea, Jesus; Martí, Itxaso; Vioque, Jesus MDPI (2021-01-23)
      We assessed the association between the use of lower- and higher-than-recommended doses of folic acid supplements (FAs) during pregnancy and attentional function in boys and girls at age of 4-5. We analyzed data from 1329 ...