Listar por autoría "15bfabd2-e7c6-4935-99dc-0addaed6536f"
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Protein adsorption/desorption dynamics on Ca‑enriched titanium surfaces: biological implications
Springer (2021-08-27)Calcium ions are used in the development of biomaterials for the promotion of coagulation, bone regeneration, and implant osseointegration. Upon implantation, the time-dependent release of calcium ions from titanium implant ... -
Proteome analysis of human serum proteins adsorbed onto different titanium surfaces used in dental implants
Taylor & Francis (2017)Titanium dental implants are commonly used due to their biocompatibility and biochemical properties; blasted acid-etched Ti is used more frequently than smooth Ti surfaces. In this study, physico-chemical characterisation ...
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Proteomic analysis of calcium-enriched sol–gel biomaterials
Springer (2019-04)Calcium is an element widely used in the development of biomaterials for bone tissue engineering as it plays important roles in bone metabolism and blood coagulation. The Ca ions can condition the microenvironment at the ...
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Proteomic Analysis of Mesenchymal Stem Cells and Monocyte Co-Cultures Exposed to a Bioactive Silica-Based Sol–Gel Coating
American Chemical Society (2023)New methodologies capable of extensively analyzing the cell-material interactions are necessary to improve current in vitro characterization methods, and proteomics is a viable alternative. Also, many studies are focused ...
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Proteomic analysis of silica hybrid sol-gel coatings: a potential tool for predicting the biocompatibility of implants in vivo
Taylor & Francis (2017)The interactions of implanted biomaterials with the host organism determine the success or failure of an implantation. Normally, their biocompatibility is assessed using in vitro tests. Unfortunately, in vitro and in vivo ...
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Proteomic evaluation of human osteoblast responses to titanium implants over time
Wiley (2022-08-30)Titanium is widely used in bone prostheses due to its excellent biocompatibility and osseointegration capacity. To understand the effect of sandblasted acid-etched (SAE) Ti implants on the biological responses of human ...
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Proteomics as a tool to study the osteoimmunomodulatory role of metallic ions in a sol–gel coating
Royal Society of Chemistry (2023)The success of bone implants depends on the osteoimmunomodulatory (OIM) activity of the biomaterials in the interactions with the periimplantary tissues. Many in vitro tests have been conducted to evaluate the osteoimmunology ...
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Silica-gelatin hybrid sol-gel coatings: A proteomic study with biocompatibility implications
Wiley (2018-05)Osseointegration, including the foreign body reaction to biomaterials, is an immune‐modulated, multifactorial, and complex healing process in which various cells and mediators are involved. The buildup of the osseointegration ...
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Sol-gel coatings for metallic prosthesis from methyl-modified alkoxysilanes: balance between protection and bioactivation
Elsevier (2020)The reported osteogenic properties of the hybrid silica sol-gel materials make these compositions perfect candidates for bone tissue engineering applications. The aim of this study was the synthesis and characterisation ...
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Study of the degradation of hybrid sol–gel coatings in aqueous medium
Elsevier (2014-11)The design and development of suitable multilayered functional coatings for delaying corrosion advance in metals and become controlled-release vehicles requires that the properties of the coatings are known. Coatings ... -
Synthesis and characterization of silica-chitosan hybrid materials as antibacterial coatings for titanium implants
Elsevier (2019-01)To avoid dental implant-related infections and to promote the osseointegration of titanium implants, the application of silicon and chitosan containing coatings is proposed. Silicon is a well-known osteogenic element and ...
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Synthesis of hybrid sol-gel materials and their biological evaluation with human mesenchymal stem cells
Springer (2013-03)Surface engineering of biomaterials could promote the osseointegration of implants. In this work, two types of hybrid sol–gel materials were developed to stimulate cell attachment, proliferation and differentiation of ...
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The effect of calcium–magnesium mixtures in sol–gel coatings on bone tissue regeneration
Royal Society of Chemistry (2022)Calcium and magnesium are two elements essential for bone structure and metabolism. However, their synergistic or competitive effects on bone regeneration are often overlooked during biomaterial development. We examined ...
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The effect of strontium incorporation into sol-gel biomaterials on their protein adsorption and cell interactions
Elsevier (2019-02-01)It is known strontium can both inhibit the osteoclast formation and stimulate the osteoblast maturation, so biomaterials containing this element can favour bone structure stabilisation. The addition of Sr to biomaterials ...
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Using osteogenic medium in the in vitro evaluation of bone biomaterials: Artefacts due to a synergistic effect
Elsevier (2023)In vitro tests using bone cells to evaluate the osteogenic potential of biomaterials usually employ the osteogenic medium (OM). The lack of correlation frequently reported between in vitro and in vivo studies in bone ...
